Results 141 to 150 of about 9,145 (201)

Methionine-enkephalin, leucine-enkephalin, methionine-enkephalin-Arg6-Phe7 and methionine-enkephalin-Arg6-Gly7-Leu8 in human pheochromocytoma

Life Sciences, 1983
Methionine-enkephalin(met-enkephalin)-, leucine-enkephalin(leu-enkephalin)-, methionine-enkephalin-Arg6-Phe7(met-enkephalin-Arg-Phe)- and methionine-enkephalin-Arg6-Gly7-Leu8(met-enkephalin-Arg-Gly-Leu)-like immunoreactivities(-LI) were studied in 16 pheochromocytomas by radioimmunoassays (RIAs) for these four opioid peptides. Met-enkephalin-Arg-Phe-LI
T, Yoshimasa, K, Nakao, Y, Ikeda, M, Sakamoto, M, Suda, H, Imura   +5 more
openaire   +2 more sources

Demonstration and characterization of immunoreactive methionine-enkephalin, leucine-enkephalin, methionine-enkephalin-Arg6-Gly7-Leu8 and methionine-enkephalin-Arg6-Phe7 in human phaeochromocytoma

Acta Endocrinologica, 1984
Abstract. To elucidate whether or not human phaeochromocytoma contains methionine-enkephalin-Arg6-Gly7-Leu8 (Met-enkephalin-Arg-Gly-Leu) and methionine-enkephalin-Arg6-Phe7 (Met-enkephalin-Arg-Phe) together with methionine-enkephalin (Met-enkephalin) and leucine-enkephalin (Leu-enkephalin), all of which are known to exist in the same precursor molecule
Takaaki Youshimasa, Kazuwa Nakao, Makoto Sakamoto, Mitsuaki Suda, Narito Morii, Yoshio Ikeda, Takashi Ishihara, Masataka Manno, Satoshi Hamada, Shinichiro Shimbo, Toru Mori, Teruya Yoshimi, Shigeru Matsukura, Hiroo Imura   +13 more
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Methionine–enkephalin related glycoconjugates

International Journal of Peptide and Protein Research, 1993
A series of glycoconjugates, in which [Met5]enkephalin or [d‐Ala2, Met5]enkephalin have been linked through an ester bond to the HO‐6 of various d‐glycopyranose moieties, were synthesized by classical solution methods. The biological activities of these compounds were determined on selective pharmacological preparations: guinea pig ileum and mouse vas ...
Š. HORVAT, J. HORVAT, L. VARGA‐DEFTERDAROVIĆ, K. PAVELIĆ, N.N. CHUNG, P.W. SCHILLER   +5 more
openaire   +3 more sources

Crystal structure of methionine-enkephalin

Biochemical and Biophysical Research Communications, 1986
The crystal structure of methionine-enkephalin has been determined by X-ray crystallography. There are two independent pentapeptides in the asymmetric unit and both display extended backbone conformations with their side chains arranged alternately below and above the backbone plane.
D, Mastropaolo, A, Camerman, N, Camerman
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Parallel distribution of methionine-enkephalin-arg6-gly7-leu8 with methionine-enkephalin, leucine-enkephalin and methionine-enkephalin-arg6-phe7 in human and bovine brains

Life Sciences, 1983
Using specific radioimmunoassays(RIAs) for methionine-enkephalin(Met-Enk), leucine-enkephalin(Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg-Gly-Leu) and methionine-enkephalin-Arg6-Phe7 (Met-Enk-Arg-Phe), we studied the regional distribution of these opioid peptides in human and bovine brains.
Y, Ikeda, K, Nakao, T, Yoshimasa, M, Sakamoto, M, Suda, N, Yanaihara, H, Imura   +6 more
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Totalsynthese von Methionin‐Enkephalin

Angewandte Chemie, 1976
Zwanzigfache Normorphin‐Wirkung zeigt das aus Schweinehirn isolierte Pentapeptid (1), das man infolgedessen auch als „endogenes Opiat”︁ bezeichnet hat. Jetzt wird die Totalsynthese dieses Stoffes beschrieben magnified image.
Wolfgang Voelter, Claus Bürvenich, Hans Horn, Hubert Kalbacher, Emanuel Pietrzik   +4 more
openaire   +1 more source

OCCURRENCE OF METHIONINE-ENKEPHALIN-ARG6-GLY⁷-LEU⁸WITH METHIONINE-ENKEPHALIN, LEUCINE-ENKEPHALIN AND METHIONINE-ENKEPHALIN-ARG6-PHE⁷IN HUMAN GASTRIC ANTRUM.

The Journal of Clinical Endocrinology & Metabolism, 1983
Recent studies on the nucleotide sequence of cloned DNA complementary to mRNA for preproenkephalin from bovine adrenal medulla and human pheochromocytoma have revealed that this precursor molecule contains four copies of methionine-enkephalin (Met-Enk) and one copy each of leucine-enkephalin (Leu-Enk), methionine-enkephalin-Arg6-Gly7-Leu8 (Met-Enk-Arg6-
M, Sakamoto, K, Nakao, T, Yoshimasa, Y, Ikeda, M, Suda, K, Takasu, S, Shimbo, N, Yanaihara, H, Imura   +8 more
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ENZYME IMMUNOASSAY FOR METHIONINE‐ENKEPHALIN SULFOXIDE

Clinical and Experimental Pharmacology and Physiology, 1990
SUMMARY1. An immunoassay technique employing an enzyme‐labelled ligand was developed for the sulfoxide derivative of the opioid peptide methionine‐enkephalin (MOE).2. The sensitivity of the enzyme immunoassay (EIA) was approximately twofold higher than that achieved in the radio‐immunoassay (RIA) using tritiated ligand.
G K, Tiong, J E, Olley
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Methionine‐enkephalin peptides in human teeth

International Journal of Peptide and Protein Research, 1988
The presence of the free opioid pentapeptide methionine enkephalin (ME) and of ME‐containing peptide(s) was established firmly in decalcified, depulped human teeth by using a combination of methods including RP‐HPLC, radioimmunoassay, radioreceptorassay, trypsin, carboxypeptidase B, fast atom bombardment mass spectrometry, and MS/MS methodology ...
F S, Tanzer, E, Tolun, G H, Fridland, C, Dass, J, Killmar, P W, Tinsley, D M, Desiderio   +6 more
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Synaptic mechanism of methionine-enkephalin uptake

Life Sciences, 1982
The actions of classical neurotransmitters at the synapse are rapidly terminated either by re-uptake or by enzymatic degradation. Enkephalins, like other neurotransmitters, have been demonstrated to be degraded by active proteinases present in the brain. However, it has been generally assumed that an uptake process is not operant for met-enkephalin. To
B P, Roy, I, Jamal, J, Go
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