Results 91 to 100 of about 487,006 (336)
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Evolving towards a European administration of the issues of Freedom, Security and Justice [PDF]
Revista CIDOB d'Afers Internacionals, 2010 Building Europe is a process that, for 50 years, has been characterised by a high degree of uncertainty, guided more by pragmatism than by ideological or dogmatic factors.
Pablo Acosta Gallo
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
The National Legislatures in the Enlargement of Mercosur: Paraguay’s Acceptance of Venezuela and Bolivia [PDF]
, 2023 André Leite Araujo
openalex +1 more source
FEBS Letters, EarlyView.At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom +3 more
wiley +1 more source
Accession to the EU’s Competition Law Regime: A Law and Governance Approach [PDF]
Yearbook of Antitrust and Regulatory Studies, 2014 The aim of this paper is to analyse the interplay between the EU’s external (pre-accession) and internal (post-accession) governance model in the field of competition law and to reach a deeper understanding of the EU’s Europeanization strategy at the ...
Katalin J. Cseres
doaj
Poststreptococcal Dystonia with Bilateral Striatal Enlargement: MR Imaging and Spectroscopic Findings [PDF]
, 2008 Ayşe Tuba Karagülle Kendi +5 more
openalex +1 more source
Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source
EU ENLARGEMENT AT A CROSSROADS [PDF]
CES Working Papers, 2012 The present article aims to explore the general theme of the EU enlargement strategy in the new 2012 European context. Until now, the EU’s enlargement strategy has yielded impressive results.
Andreea Cătălina Paul
doaj