Cefiderocol (Fetroja) as a Treatment for Hospital-Acquired Pneumonia [PDF]
With increasing resistance to conventional antibiotic treatments, especially among gram-negative bacilli, the search for new antibiotics has become critical on a global scale.
Ahmadzadeh, Shahab +10 more
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Molecular epidemiology of carbapenem-resistant Enterobacterales colonization in an intensive care unit. [PDF]
, 2021 Masters Degree. University of KwaZulu-Natal, Durban.Background: Due to the high association with mortality and morbidity, carbapenem-resistant Enterobacterales (CRE) in general, and carbapenem-resistant Klebsiella pneumoniae, in particular, have been ...
Madni, Osama.
core
Biochemical and molecular characterization of GES and NDM engineered variants: interactions with β-lactams and inhibitors [PDF]
, 2019 Antibiotic resistance occurs when bacteria causing an infection survive after being exposed to a drug that, under normal conditions, would kill it or inhibit its growth.
PICCIRILLI, ALESSANDRA
core
Restoring cefepime activity against multidrug-resistant KPC-producing Klebsiella pneumoniae by combination with boronic acid inhibitors, MB076 and S02030 [PDF]
: Foremost in the design of new β-lactamase inhibitors (BLIs) are the boronic acid transition state inhibitors (BATSIs). Two highly potent BATSIs being developed are S02030 and MB076 strategically designed to be active against cephalosporinases and ...
Bonomo R. A. +15 more
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Gesetzliche Verpflichtungen des RKI und BfArM im Rahmen der Einstufung von Reserveantibiotika [PDF]
Antibiotikaresistenzen sind eine zunehmende Bedrohung und führen jährlich zu ca. 1,27 Millionen Todesfällen weltweit. Um dem zu begegnen, werden global und in Deutschland Konzepte entwickelt, die in der Regel auf multisektoralen Maßnahmen basieren ...
Abu Sin, Muna +6 more
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Biofilm and wastewater dynamics in an activated-sludge process in the UK: insights into microbiome composition, metabolic activity, and antimicrobial resistance using 16S rRNA sequencing [PDF]
This study explores the bacterial microbiome contributing to the resistome in wastewater and biofilm communities within a wastewater treatment works in Scotland, UK.
Craft, John +4 more
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Estimating the Value of Aztreonam-Avibactam in Treating Metallo-beta-Lactamase-Producing Enterobacterales Infections in Spain Using the STEDI AMR Value Framework [PDF]
Antimicrobial resistance; Carbapenem-resistance; Cost effectivenessResistencia antimicrobiana; Resistencia a carbapenémicos; Coste-efectividadResistència antimicrobiana; Resistència a carbapenèmics; Cost-efectivitatIntroduction Treatments for serious ...
de Lossada, Alfonso +6 more
core +1 more source
Resistance to oxyimino-cephalosporins conferred by an alternative mechanism of hydrolysis by the Acinetobacter-derived cephalosporinase-33 (ADC-33), a class C β-lactamase present in carbapenem-resistant Acinetobacter baumannii (CRAb) [PDF]
Antimicrobial resistance in Acinetobacter baumannii is partly mediated by chromosomal class C beta-lactamases, the Acinetobacter-derived cephalosporinases (ADCs).
Bethel, Christopher R. +12 more
core +1 more source
Resistance to antimicrobials [PDF]
La resistència als antimicrobians és una amenaça greu per a la salut pública, reconeguda com una emergència mundial. Tot i ser eclipsada per la pandèmia de la COVID-19, continua sent un problema crucial, amb milions de morts anuals per infeccions ...
González-López, Juan José +2 more
core +2 more sources