Results 101 to 110 of about 66,888 (297)

Genes termorregulados diferencialmente expressos em Conidiobolus lamprauges Thermoregulated genes differentially expressed in Conidiobolus lamprauges

Ciência Rural, 2012
Conidiobolus lamprauges é um fungo zigomiceto patógeno de humanos e animais, causador da conidiobolomicose, caracterizada por uma rinossinusite crônica granulomatosa severa.
Josiane Aparecida Gonçalina da Silva, Daphine Ariadne Jesus de Paula, Marcelo Marques da Silveira, Maria Cristina da Silva, Laila Natasha Santos Brandão, Leticia Camara Pitchenin, Luciano Nakazato, Valéria Dutra   +7 more
doaj  

Giardiavirus rewires host translation and glycolytic metabolism to support its replication in Giardia duodenalis

Virulence
Giardia duodenalis is an intestinal protozoan parasite responsible for giardiasis, a disease primarily characterized by diarrhea and associated with long-term complications such as malnutrition and growth impairment in children.
Lu Li, Lili Cao, Chongli Zhong, Nan Zhang, Xin Li, Xiaocen Wang, Yanbing Guo, Yanhui Yu, Jianhua Li, Xichen Zhang, Yukun Le, Jianqi Yuan, Pengtao Gong   +12 more
doaj   +1 more source

Fungal Enolase, β-Tubulin, and Chitin Are Detected in Brain Tissue from Alzheimer’s Disease Patients

Frontiers in Microbiology, 2016
Recent findings provide evidence that fungal structures can be detected in brain tissue from Alzheimer’s disease (AD) patients using rabbit polyclonal antibodies raised against whole fungal cells.
D. Pisa, R. Alonso, A. Rábano, M. N. Horst, Luis Carrasco   +4 more
semanticscholar   +1 more source

Ion Activation Methods for Top‐Down Proteomics

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) has emerged as a premier method used to characterize the sequences of proteins. Top‐down proteomics aims to capture the multiple sources of structural diversity reflected in proteins, such as those that arise from alternative RNA splicing events or the addition of post‐translational modifications. Tandem MS (i.e., MS/MS)
Jada N. Walker, Jennifer S. Brodbelt
wiley   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

Identification of plasminogen-binding sites in Streptococcus suis enolase that contribute to bacterial translocation across the blood-brain barrier

Frontiers in Cellular and Infection Microbiology
Streptococcus suis is an emerging zoonotic pathogen that can cause invasive disease commonly associated with meningitis in pigs and humans. To cause meningitis, S.
Tiantong Zhao, Alex Gussak, Bart van der Hee, Sylvia Brugman, Peter van Baarlen, Jerry M. Wells   +5 more
doaj   +1 more source

Pseudomonas aeruginosa Enolase Influences Bacterial Tolerance to Oxidative Stresses and Virulence

Frontiers in Microbiology, 2016
Pseudomonas aeruginosa is a Gram negative opportunistic pathogenic bacterium, which causes acute and chronic infections. Upon entering the host, bacteria alter global gene expression to adapt to host environment and avoid clearance by the host.
Yuding Weng, Fei Chen, Yiwei Liu, Qiang Zhao, Ronghao Chen, Xiao-Lei Pan, Chang Liu, Zhi-Hui Cheng, Shou-Guang Jin, Yong-Xin Jin, Wei-Hui Wu   +10 more
semanticscholar   +1 more source

Aspartic Protease Inhibition Induces Proteomic Remodeling in Paracoccidioides brasiliensis

PROTEOMICS, EarlyView.
ABSTRACT Paracoccidioidomycosis (PCM) is a major systemic mycosis in Latin America caused by Paracoccidioides brasiliensis, yet the contribution of aspartic proteases to fungal physiology and pathogenicity remains poorly understood. Here, we employed data‐independent acquisition (DIA)‐based quantitative proteomics to investigate the impact of pepstatin
Sarah Fernandes Lima, Wilson Dias Segura, Leonardo Brogliato de Moraes, Reinaldo Souza Oliveira, Pedro Henrique Corteletti Manfio, Alison Felipe Alencar Chaves, Wagner Luiz Batista   +6 more
wiley   +1 more source

Proinflammatory Cytokines, Enolase and S-100 as Early Biochemical Indicators of Hypoxic-Ischemic Encephalopathy Following Perinatal Asphyxia in Newborns

Pediatrics and Neonatology, 2017
Estimation of the neurological prognosis of infants suffering from perinatal asphyxia and signs of hypoxic-ischemic encephalopathy is of great clinical importance; however, it remains difficult to satisfactorily assess these signs with current standard ...
Verónica Chaparro-Huerta, Mario Eduardo Flores-Soto, Mario Ernesto Merin Sigala, Juan Carlos Barrera de León, María de Lourdes Lemus-Varela, Blanca Miriam de Guadalupe Torres-Mendoza, Carlos Beas-Zárate   +6 more
doaj   +1 more source

Alpha-enolase on apical surface of renal tubular epithelial cells serves as a calcium oxalate crystal receptor

Scientific Reports, 2016
To search for a strategy to prevent kidney stone formation/recurrence, this study addressed the role of α-enolase on apical membrane of renal tubular cells in mediating calcium oxalate monohydrate (COM) crystal adhesion.
Kedsarin Fong‐ngern, V. Thongboonkerd
semanticscholar   +1 more source