Results 111 to 120 of about 43,584 (222)

Extracellular Vesicles in the Biology and Liquid Biopsy Diagnostics of Pediatric High‐Grade Glioma – Emerging Findings and Opportunities

open access: yesJournal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Liquid biopsy has emerged as an important diagnostic paradigm impacting care across multiple cancer indications. This is also an area of great interest in pediatric solid tumours, including those affecting the central nervous system (CNS). Of special concern are pediatric high‐grade gliomas (pHGGs) due to the associated diagnostic complexities,
Samia Jahouri   +6 more
wiley   +1 more source

Applying Distinct CDMS Strategies to Observe Nonclassical Virus Capsid Assembly

open access: yesJournal of Mass Spectrometry, Volume 61, Issue 6, June 2026.
ABSTRACT In conventional native mass spectrometry (MS), one faces severe limitations when challenged with heterogeneous, high‐mass samples, commonly failing to resolve clear peak distributions, and thus mass determination. Charge detection MS (CDMS) has emerged as a premier method to analyze these samples by determining mass‐to‐charge ratio (m/z) and ...
Lars Thiede   +14 more
wiley   +1 more source

GRKs and arrestins: Nomenclature and functions in GPCR‐dependent and ‐independent signalling

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 11, Page 2619-2633, June 2026.
G protein‐coupled receptor (GPCR) kinases (GRKs) and arrestins play a critical role in the regulation of GPCR signalling. Historic names of mammalian GRKs were replaced by systematic ones in the 1990s; however, both kinds of names are currently in use for mammalian arrestins.
Vsevolod V. Gurevich
wiley   +1 more source

Periorbitale heliotrope Erytheme mit Ödem als potenzieller klinischer Indikator für eine paraneoplastische Dermatomyositis – eine Fallserie

open access: yesJDDG: Journal der Deutschen Dermatologischen Gesellschaft, Volume 24, Issue 6, Page 731-736, June 2026.
Zusammenfassung Die Dermatomyositis (DM) im Erwachsenenalter kann eine enge Assoziation mit Malignomen aufweisen, insbesondere bei Nachweis von Anti‐TIF1‐γ‐ oder Anti‐NXP‐2‐Antikörpern. Diese Fallserie beschreibt zehn Fälle von DM mit ausgeprägten periorbitalen heliotropen Erythemen und Ödemen (PHEÖ), in der bei neun Patienten in der apparativen ...
Antigona Aliu   +10 more
wiley   +1 more source

PPT1‐mediated plastidic phosphoenolpyruvate import enhances fatty acid biosynthesis in sugar‐rich tissues

open access: yesNew Phytologist, Volume 250, Issue 6, Page 3900-3913, June 2026.
Summary Metabolic engineering of vegetative tissues for lipid production holds transformative potential for sustainable biofuels, yet achieving sufficient yields remains challenging. Here, we present a strategy to enhance fatty acid synthesis by redirecting cytosolic phosphoenolpyruvate (PEP) into plastids through overexpression of the plastidial ...
Jiang Wang   +6 more
wiley   +1 more source

Non‐HLA Autoantibodies Associate With a Positive Flow‐Crossmatch Pre‐ and Chronic Lung Allograft Dysfunction Post‐ Lung Transplant

open access: yesHLA, Volume 107, Issue 6, June 2026.
ABSTRACT Antibodies to HLA are a major cause of chronic lung allograft dysfunction (CLAD) following lung transplantation (LTx), however mounting evidence indicates non‐HLA autoantibodies may also play a role. LTx recipients may have increased autoantibodies related to their native disease, and these may impact both pre‐transplant assays and LTx ...
Steven Hiho   +7 more
wiley   +1 more source

Mitochondrial‐Haplotype Influences Plasma Metabolome, Lipidome, and Proteome in a Sex Specific Manner in the Genetically Heterogenous OKC‐HETB/W Rat

open access: yesThe FASEB Journal, Volume 40, Issue 10, 31 May 2026.
Multi‐omics profiling uncovers the effect of sex and mitochondrial‐haplotype on molecular fingerprints of aging in plasma. ABSTRACT The effect of mitochondrial‐haplotype (mt‐haplotype) on aging was studied using a unique rat model (OKC‐HETB/W), which has a heterogenous nuclear background combined with mitochondria from either Brown Norway (B‐haplotype)
Hoang Van M. Nguyen   +13 more
wiley   +1 more source

Correction: Exposure of HL-60 human leukaemic cells to 4-hydroxynonenal promotes the formation of adduct(s) with α-enolase devoid of plasminogen binding activity. [PDF]

open access: yesBiochem J
Barrera G   +14 more
europepmc   +1 more source

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