Results 131 to 140 of about 66,888 (297)

Light signaling controls chloroplast pyruvate metabolism through the STF1/2–PKP1 module in soybean

Journal of Integrative Plant Biology, EarlyView.
In soybean, light‐responsive proteins switch on GmPKP1, which boosts chloroplast pyruvate production. This increases pigments, photosynthesis, seed oil, pod number, and yield, revealing a new way that light boosts crop productivity. ABSTRACT Light signaling coordinates plant development with metabolism, but the link between photoreceptors and ...
Faming Lin, Xiaoran Wang, Chenhao Zhao, Shaolong Yang, Jingnan Xu, Hongyi Su, Ruixiang Lei, Yilei Xu, Jike Xue, Ming Chang, Fanjiang Kong, Ran Wang   +11 more
wiley   +1 more source

Quantitative analysis of intrarenal nerve‐associated profiles in the human foetal kidney between 14 and 30 gestational weeks: An S100 immunohistochemical study

Journal of Anatomy, EarlyView.
S100 immunohistochemistry and digital morphometry were used to characterise nerve‐associated profiles in human foetal kidneys from 14 to 30 gestational weeks. Cortical S100‐positive area increased with gestational age and was positively associated with foetal weight and maturation zone thickness.
Ivan Petrović, Ana Balenović, Milana Bosanac, Srdjan Stanković, Isidora Milosavljević, Milena Šunjević, Sandra Trivunić Dajko, Bojana Andrejić‐Višnjić   +7 more
wiley   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold, Chia Wei Cheah, Rathna Devi Vaithilingam   +2 more
wiley   +1 more source

Rapid Translation of the Early Coding Region Promotes Premature Transcription Termination, Reducing Protein Expression in Escherichia coli

Molecular Microbiology, EarlyView.
A run of consecutive fast‐translated codons (right) within the first 30 codons of lacZ (top) causes loss of the downstream transcript at positions coinciding with previously mapped intragenic Rho‐dependent termination sites (middle), and a corresponding loss of β‐galactosidase activity (bottom).
Steen Pedersen, Alberte Honoré Jepsen, Bertil Gummesson, Namiko Mitarai, Kim Sneppen, Sine Lo Svenningsen   +5 more
wiley   +1 more source

Gene Editing of Nicotiana benthamiana Architecture for Space‐Efficient Production of Recombinant Proteins in Closed Environments

Plant Biotechnology Journal, EarlyView.
ABSTRACT Indoor vertical farming (VF) offers practical advantages for the cultivation of plant protein bio‐factories including plant uniformity, product consistency, water/nutrient recycling and production cycles on a year‐round basis. Much progress has been achieved toward the development of innovative systems for artificial lighting, automated ...
Béatrice Giroux, Kristina LeBreux, Louis Feyzeau, Marie‐Claire Goulet, Charles Goulet, Dominique Michaud   +5 more
wiley   +1 more source

Nitroalkylation Mediated by Nitro‐Fatty Acids Is Involved in Key Physiological Processes During Arabidopsis thaliana Development

Plant, Cell &Environment, EarlyView.
ABSTRACT Nitro‐fatty acids (NO2‐FAs) are potent electrophiles that react with nucleophilic residues in proteins (cysteines, histidines and lysines) via a process known as nitroalkylation. This reversible post‐translational modification (PTM) functions as a selective signalling mechanism by modulating the structure, transport, and catalysis of target ...
Lorena Aranda‐Caño, Raquel Valderrama, Mounira Chaki, Juan Carlos Begara‐Morales, José Rafael Pedrajas, Manuel Melguizo, Matín Moret, Aureliano Bombarely, Francisco Luque, Juan Bautista Barroso   +9 more
wiley   +1 more source

Understanding extracellular vesicle biology, isolation, and characterization: The theory of EV‐erything

Periodontology 2000, EarlyView.
Abstract Background Extracellular vesicles (EVs), especially exosomes, are nanoparticles increasingly recognized as key regulators of intercellular communication in both physiological and pathological aspects. Despite rapid progress, inconsistencies in nomenclature, isolation, and characterization continue to restrict translational advancement.
Paras Ahmad, Nima Farshidfar, Nathan E. Estrin, Yulan Wang, Yufeng Zhang, Anton Sculean, Richard J. Miron   +6 more
wiley   +1 more source

Thermoregulatory and plasma neurobiomarker responses to heat tolerance assessment in exertional heat illness and matched controls

Experimental Physiology, EarlyView.
Abstract Exercise in the heat and elevated tissue temperature are associated with neuronal stress and changes in blood–brain barrier (BBB) function. More severe thermal insult may manifest as exertional heat illness (EHI) and complication by central nervous system (CNS) dysfunction may persist post‐EHI.
Tom W. Palin, Jo Corbett, Lisa J. Hill, David R. Woods, Alex A. M. Gould, Barney Wainwright, James A. Roberts, Chloe N. Thomas, Daniel Snape, Carol House, Omar Tayari, Richard J. Elsworthy, James L. Mitchell, Andrew J. Roberts, John P. O'Hara, Michael J. Stacey   +15 more
wiley   +1 more source