Results 31 to 40 of about 66,888 (297)
Enolase Isoenzymes as Tumour Markers [PDF]
Clinical Chemistry and Laboratory Medicine, 1986 alpha- and gamma-enolase isoenzyme substance concentrations were measured in serum and plasma from healthy subjects and from 174 patients with different solid tumours. While alpha-enolase was found to be increased in the plasma of patients with tumours of quite different origin, gamma-enolase apparently reflected malignancies of the neuroendocrine ...
GERBITZ, K.-D. +5 more
openaire +3 more sources
Journal of Biological Chemistry, 1996 Hypoxia-inducible factor 1 (HIF-1) is a basic helix-loop-helix transcription factor which is expressed when mammalian cells are subjected to hypoxia and which activates transcription of genes encoding erythropoietin, vascular endothelial growth factor ...
G. Semenza +6 more
semanticscholar +1 more source
Experimental and bioinformatic approach to identifying antigenic epitopes in human α- and β-enolases
Biochemistry and Biophysics Reports, 2018 Human α- and β-enolases are highly homologous enzymes, difficult to differentiate immunologically. In this work, we describe production, purification and properties of anti-α- and anti-β-enolase polyclonal antibodies.
Jadwiga Pietkiewicz +8 more
doaj +1 more source
A multi-method and structure-based in silico vaccine designing against Echinococcus granulosus through investigating enolase protein [PDF]
BioImpacts, 2019 Introduction: Hydatid disease is a ubiquitous parasitic zoonotic disease, which causes different medical, economic and serious public health problems in some parts of the world.
Mohammad Mostafa Pourseif +4 more
doaj +1 more source
Lack of association of S100β and neuron-specific enolase with mortality in critically ill patients
Brazilian Journal of Psychiatry, 2013 Objective: To evaluate the relationship between brain damage biomarkers and mortality in the intensive care unit (ICU). Methods: The sample comprised 70 patients admitted to an ICU.
Roberta Candal de Macedo +10 more
doaj +1 more source
Nature Communications, 2018 The molecular mechanisms underlying the metabolic shift toward increased glycolysis observed in pulmonary artery smooth muscle cells (PASMC) during the pathogenesis of pulmonary arterial hypertension (PAH) are not fully understood.
J. Dai +5 more
semanticscholar +1 more source
Neuron-Specific Enolase—What Are We Measuring?
International Journal of Molecular SciencesSince the discovery of the neuron-specific protein by Moore and McGregor in 1965, tens of thousands of studies have investigated the basic and applied significance of neuron-specific enolase (NSE). This promising biomarker, according to many researchers,
A. S. Babkina +4 more
semanticscholar +1 more source
Multifunctional neuron-specific enolase: its role in lung diseases
Bioscience Reports, 2019 Neuron-specific enolase (NSE), also known as gamma (γ) enolase or enolase-2 (Eno2), is a form of glycolytic enolase isozyme and is considered a multifunctional protein.
Caiming Xu +7 more
semanticscholar +1 more source
Dancing to Another Tune—Adhesive Moonlighting Proteins in Bacteria
Biology, 2014 Biological moonlighting refers to proteins which express more than one function. Moonlighting proteins occur in pathogenic and commensal as well as in Gram-positive and Gram-negative bacteria.
Veera Kainulainen, Timo K. Korhonen
doaj +1 more source
An alternative vaccine target for bovine Anaplasmosis based on enolase, a moonlighting protein
Frontiers in Veterinary Science, 2023 The discovery of new targets for preventing bovine anaplasmosis has moved away from focusing on proteins that have already been extensively studied in Anaplasma marginale, including the Major Surface Proteins, Outer Membrane Proteins, and Type IV ...
Rosa Estela Quiroz-Castañeda +2 more
doaj +1 more source