Results 31 to 40 of about 54,547 (286)

Fish allergens at a glance: Variable allergenicity of parvalbumins, the major fish allergens

open access: yesFrontiers in Immunology, 2014
Fish is a common trigger of severe, food-allergic reactions. Only a limited number of proteins induce specific IgE-mediated immune reactions. The major fish allergens are the parvalbumins.
Annette eKuehn   +5 more
doaj   +1 more source

An alternative vaccine target for bovine Anaplasmosis based on enolase, a moonlighting protein

open access: yesFrontiers in Veterinary Science, 2023
The discovery of new targets for preventing bovine anaplasmosis has moved away from focusing on proteins that have already been extensively studied in Anaplasma marginale, including the Major Surface Proteins, Outer Membrane Proteins, and Type IV ...
Rosa Estela Quiroz-Castañeda   +2 more
doaj   +1 more source

Consensus Enolase of Trypanosoma Cruzi: Evaluation of Their Immunogenic Properties Using a Bioinformatics Approach

open access: yesLife, 2022
There is currently no vaccine against American trypanosomiasis, caused by the parasite Trypanosoma cruzi. This is due to the genomic variation observed in the six DTUs of T. cruzi.
Alejandro Diaz-Hernandez   +5 more
doaj   +1 more source

Host HSPD1 Translocation from Mitochondria to the Cytoplasm Induced by Streptococcus suis Serovar 2 Enolase Mediates Apoptosis and Loss of Blood–Brain Barrier Integrity

open access: yesCells, 2022
Streptococcus suis serovar 2 (S. suis serovar 2) is a zoonotic pathogen that causes meningitis in pigs and humans, and is a serious threat to the swine industry and public health. Understanding the mechanism(s) by which S.
Tong Wu   +8 more
doaj   +1 more source

Identification of novel pig and human immunoglobulin G-binding proteins and characterization of the binding regions of enolase from Streptococcus suis serotype 2

open access: yesAMB Express, 2020
Streptococcus suis, a major emerging pathogen in swine and humans, expresses immunoglobulin G (IgG)-binding proteins (IBPs), which contribute to the ability of organism to evasion of host immune system.
Quan Li   +4 more
doaj   +1 more source

RopB-regulated SpeB cysteine protease degrades extracellular vesicles-associated streptolysin O and bacterial proteins from group A Streptococcus

open access: yesVirulence, 2023
Extracellular vesicles (EVs) can be released from gram-positive bacteria and would participate in the delivery of bacterial toxins. Streptococcus pyogenes (group A Streptococcus, GAS) is one of the most common pathogens of monomicrobial necrotizing ...
Chuan Chiang-Ni   +7 more
doaj   +1 more source

Enolase

open access: yes, 2007
The enolase protein of the human malarial parasite Plasmodium falciparum has recently been characterized. Apart from its glycolytic function, enolase has also been shown to possess antigenic properties and to be present on the cell wall of certain ...
Shobhona Sharma   +9 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Yeast model of human ββ-enolase deficiency disease : characterization of G157D yeast enolase [PDF]

open access: yes, 2006
Enolase is an essential enzyme in glycolysis and gluconeogenesis. In 2001, the first known case of a human disorder diagnosed as muscle enolase deficiency was found (Comi et al., 2001).
Choy, Bonny Shu Fen
core   +1 more source

Structural Characterization of Haemophilus influenzae Enolase and Its Interaction with Human Plasminogen by In Silico and In Vitro Assays

open access: yesPathogens, 2021
Haemophilus influenzae is the causal agent of invasive pediatric diseases, such as meningitis, epiglottitis, pneumonia, septic arthritis, pericarditis, cellulitis, and bacteremia (serotype b). Non-typeable H. influenzae (NTHi) strains are associated with
Yesenia Osorio-Aguilar   +7 more
doaj   +1 more source

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