Results 41 to 50 of about 66,888 (297)

Multifunctional roles of γ-enolase in the central nervous system: more than a neuronal marker

Cell & Bioscience
Enolase, a multifunctional protein with diverse isoforms, has generally been recognized for its primary roles in glycolysis and gluconeogenesis. The shift in isoform expression from α-enolase to neuron-specific γ-enolase extends beyond its enzymatic role.
Selena Horvat, J. Kos, A. Pišlar
semanticscholar   +1 more source

Fish allergens at a glance: Variable allergenicity of parvalbumins, the major fish allergens

Frontiers in Immunology, 2014
Fish is a common trigger of severe, food-allergic reactions. Only a limited number of proteins induce specific IgE-mediated immune reactions. The major fish allergens are the parvalbumins.
Annette eKuehn, Ines eSwoboda, Karthik eArumugam, Christiane eHilger, François eHentges, François eHentges   +5 more
doaj   +1 more source

Consensus Enolase of Trypanosoma Cruzi: Evaluation of Their Immunogenic Properties Using a Bioinformatics Approach

Life, 2022
There is currently no vaccine against American trypanosomiasis, caused by the parasite Trypanosoma cruzi. This is due to the genomic variation observed in the six DTUs of T. cruzi.
Alejandro Diaz-Hernandez, Maria Cristina Gonzalez-Vazquez, Minerva Arce-Fonseca, Olivia Rodríguez-Morales, Maria Lilia Cedillo-Ramirez, Alejandro Carabarin-Lima   +5 more
doaj   +1 more source

Host HSPD1 Translocation from Mitochondria to the Cytoplasm Induced by Streptococcus suis Serovar 2 Enolase Mediates Apoptosis and Loss of Blood–Brain Barrier Integrity

Cells, 2022
Streptococcus suis serovar 2 (S. suis serovar 2) is a zoonotic pathogen that causes meningitis in pigs and humans, and is a serious threat to the swine industry and public health. Understanding the mechanism(s) by which S.
Tong Wu, Li Jia, Siyu Lei, Hexiang Jiang, Jianan Liu, Na Li, Paul R. Langford, Hongtao Liu, Liancheng Lei   +8 more
doaj   +1 more source

RopB-regulated SpeB cysteine protease degrades extracellular vesicles-associated streptolysin O and bacterial proteins from group A Streptococcus

Virulence, 2023
Extracellular vesicles (EVs) can be released from gram-positive bacteria and would participate in the delivery of bacterial toxins. Streptococcus pyogenes (group A Streptococcus, GAS) is one of the most common pathogens of monomicrobial necrotizing ...
Chuan Chiang-Ni, Chien-Yi Chiang, Yan-Wen Chen, Yong-An Shi, Yu-Tzu Chao, Shuying Wang, Pei-Jane Tsai, Cheng-Hsun Chiu   +7 more
doaj   +1 more source

Identification of novel pig and human immunoglobulin G-binding proteins and characterization of the binding regions of enolase from Streptococcus suis serotype 2

AMB Express, 2020
Streptococcus suis, a major emerging pathogen in swine and humans, expresses immunoglobulin G (IgG)-binding proteins (IBPs), which contribute to the ability of organism to evasion of host immune system.
Quan Li, Yang Fu, Genglin Guo, Zhuohao Wang, Wei Zhang   +4 more
doaj   +1 more source

Structural Characterization of Haemophilus influenzae Enolase and Its Interaction with Human Plasminogen by In Silico and In Vitro Assays

Pathogens, 2021
Haemophilus influenzae is the causal agent of invasive pediatric diseases, such as meningitis, epiglottitis, pneumonia, septic arthritis, pericarditis, cellulitis, and bacteremia (serotype b). Non-typeable H. influenzae (NTHi) strains are associated with
Yesenia Osorio-Aguilar, Maria Cristina Gonzalez-Vazquez, Diana Elizabeth Hernandez-Ceron, Patricia Lozano-Zarain, Ygnacio Martinez-Laguna, Cesar Raul Gonzalez-Bonilla, Rosa del Carmen Rocha-Gracia, Alejandro Carabarin-Lima   +7 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Paper-Based Surface-Enhanced Raman Scattering Lateral Flow Strip for Detection of Neuron-Specific Enolase in Blood Plasma

Analytical Chemistry, 2017
An inexpensive and disposable paper-based lateral flow strip (PLFS) has been developed as an immunoassay, in which surface-enhanced Raman scattering (SERS) is utilized for sensing signal transduction.
Xuefei Gao, Peng Zheng, Sujan Kasani, S. Wu, Feng Yang, S. Lewis, S. Nayeem, E. Engler-Chiurazzi, J. Wigginton, J. Simpkins, N. Wu   +10 more
semanticscholar   +1 more source

Neuron-Specific Enolase

The International Journal of Biological Markers, 1994
The clinical value of neuron-specific enolase as a marker in small cell lung cancer, neuroblastoma, melanoma and seminoma has been reviewed The role of serum and cerebrospinal NSE in benign and malignant disease of the central nervous sytem is discussed.
openaire   +2 more sources