Results 11 to 20 of about 66,888 (297)
Bacteriophage protein PEIP is a potent Bacillus subtilis enolase inhibitor
Cell Reports, 2022 Enolase is a highly conserved enzyme that presents in all organisms capable of glycolysis or fermentation. Its immediate product phosphoenolpyruvate is essential for other important processes like peptidoglycan synthesis and the phosphotransferase system
Sivaramesh Wigneshweraraj +2 more
exaly +2 more sources
Frontiers in Microbiology, 2022 The coagulase-negative staphylococcal (CoNS) species Staphylococcus lugdunensis is unique in causing serious infections in humans that resemble those of Staphylococcus aureus rather than those of other CoNS species.
Muzaffar Hussain +4 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2023 Significance Aerobic glycolysis and abnormal choline phospholipid metabolism are hallmarks of cancer. The inhibition of glycolysis and choline metabolism is a potential strategy for cancer treatment.
Q. Ma +16 more
semanticscholar +1 more source
Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation.
Molecules and Cells, 2022 Differentiating stem cells must coordinate their metabolism and fate trajectories. Here, we report that the catalytic activity of the glycolytic enzyme Enolase 1 (ENO1) is directly regulated by RNAs leading to metabolic rewiring in mouse embryonic stem ...
Ina Huppertz +13 more
semanticscholar +1 more source
Enolase 1, a Moonlighting Protein, as a Potential Target for Cancer Treatment
International Journal on Biological Sciences, 2021 Enolase 1 (ENO1) is a moonlighting protein, function as a glycolysis enzyme, a plasminogen receptor and a DNA binding protein. ENO1 play an important role in the process of cancer development.
Gan Qiao +4 more
semanticscholar +1 more source
Alpha-Enolase: Emerging Tumor-Associated Antigen, Cancer Biomarker, and Oncotherapeutic Target
Frontiers in Genetics, 2021 Alpha-enolase, also known as enolase-1 (ENO1), is a glycolytic enzyme that “moonlights” as a plasminogen receptor in the cell surface, particularly in tumors, contributing to cancer cell proliferation, migration, invasion, and metastasis.
F. Almaguel +3 more
semanticscholar +1 more source
Food and Agricultural Immunology, 2022 β-enolase is a heat-labile fish allergen identified in different fish species. In this study, β-enolase gene was cloned from common carp muscle tissue and the target protein was expressed as a fusion with maltose binding protein (MBP-Eno) in E.
Aistė Sližienė +6 more
semanticscholar +1 more source
Enolase Inhibitors as Early Lead Therapeutics against Trypanosoma brucei
Pathogens, 2023 Glucose metabolism is critical for the African trypanosome, Trypanosoma brucei, serving as the lone source of ATP production for the bloodstream form (BSF) parasite in the glucose-rich environment of the host blood.
Colm P. Roster +17 more
doaj +1 more source
Pathogens, 2021 Salivarian trypanosomes comprise a group of extracellular anthroponotic and zoonotic parasites. The only sustainable method for global control of these infection is through vaccination of livestock animals.
Stefan Magez +8 more
doaj +1 more source
Frontiers in Cellular and Infection Microbiology, 2022 Enolase, a multifunctional protein expressed by multiple pathogens activates plasminogen to promote proteolysis on components of the extracellular matrix, an important event in early host-pathogen interactions. A secreted form of enolase that is released
Elisa Barroeta-Echegaray +6 more
doaj +1 more source