Results 161 to 170 of about 100,569 (330)

Xanthine Derivative KMUP‐3 Alleviates Periodontal Bone Resorption by Inhibiting Osteoclastogenesis and Macrophage Pyroptosis

open access: yesJournal of Periodontal Research, EarlyView.
This study reveals that our self‐developed xanthine derivative, KMUP‐3, suppresses osteoclastogenesis, inflammation, and pyroptosis by inhibiting the NLRP3 inflammasome. It also alleviates periodontal bone loss in periodontitis rats, highlighting its potential as a novel therapeutic option for periodontitis.
Shang‐En Huang   +7 more
wiley   +1 more source

The Role of Fermentable Fibre on Endurance Exercise Capacity: A Randomised Crossover Trial of Inulin Supplementation

open access: yesNutrition Bulletin, EarlyView.
ABSTRACT Manipulation of the mouse gut microbiome has been shown to increase gut‐derived short‐chain fatty acids and improve exercise capacity. Associations between exercise performance and gut microbiome composition and metabolites have also been identified in human studies.
L. Torquati   +3 more
wiley   +1 more source

Regulation of renin gene expression in kidneys of eNOS- and nNOS-deficient mice [PDF]

open access: green, 2000
Charlotte Wagner   +5 more
openalex   +1 more source

Defective lymphatic vasculature in obesity

open access: yesObesity Reviews, EarlyView.
Summary Lymphedema is an important, and often underdiagnosed complication of obesity and is likely due to acquired defects in the lymphatic vasculature. Study of diet‐induced obesity animal models have indicated defective lymphatic vasculatures might extend to other anatomical sites, especially visceral depots.
Jingjing Zhu, John P. H. Wilding, Ji Hu
wiley   +1 more source

Pure Event Semantics

open access: yesPhilosophical Perspectives, EarlyView.
ABSTRACT In a pure event semantics for natural language, the domain of quantification and predication is limited to events and states. I offer pure event semantic analyses of several phenomena, some of which have not been treated before in formal semantics. In the pure event semantics sketched in the second section, nouns are state predicates, and this
Roger Schwarzschild
wiley   +1 more source

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