eNOS and Diabetic Nephropathy [PDF]
Diabetic nephropathy (DN) is the leading cause of end stage renal disease (ESRD) and the number of patients with DN has been increasing rapidly. Development of new effective therapeutic strategies of DN is slow at least partly because of a lack of animal models that recapitulate the features of human DN. Human variants
Feng Li, Nobuyuki Takahashi
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ANXA4 promotes trophoblast invasion via the PI3K/Akt/eNOS pathway in preeclampsia.
The inadequate trophoblast invasion is associated with the development of preeclampsia (PE). Considering that annexin A4 (ANXA4) enhances tumor invasion, we aimed to explore the functional role of ANXA4 in trophoblast cells and to examine the underlying ...
Yalan Xu+5 more
semanticscholar +1 more source
Correlation of Endothelial Nitric Oxide Synthase Gene Polymorphism (GG, TT and GT Genotype) with Proteinuria and Retinopathy in Type 2 Diabetic Patients [PDF]
Background: Nephropathy is the most important leading cause of end stage renal failure in type 2 diabetic patients, so numerous studies were done to diagnose and evaluate risk factors of diabetic nephropathy (DN).
Ali Momeni+3 more
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The effect of eight weeks of endurance training along with cinnamon extract consumption on expression of angiogenic markers in endothelial dysfunction of the coronary arteries in streptozotocin-diabetic male rats [PDF]
Purpose: Angiogenesis refers to the formation of new blood vessels from existing vessels, which is an important event in various physiological processes.
Amir Houshang Monzemi+3 more
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Reciprocal regulation of eNOS and caveolin-1 functions in endothelial cells
We hypothesized that the maintenance of vascular homeostasis is critically dependent on the expression and reciprocal regulation of caveolin-1 (Cav-1) and endothelial nitric oxide synthase (eNOS) in endothelial cells (ECs).
Zhenlong Chen+9 more
semanticscholar +1 more source
Tumour maintenance is mediated by eNOS [PDF]
Tumour cells become addicted to the expression of initiating oncogenes like Ras, such that loss of oncogene expression in established tumours leads to tumour regression. HRas, NRas or KRas are mutated to remain in the active GTP-bound oncogenic state in many cancers.
Brooke B. Ancrile+4 more
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CT-1 induces angiogenesis by regulating the ADMA/DDAH Pathway
Background. Cardiotrophin-1 (CT-1), a member of the IL-6 superfamily, is elevated in the serum of patients with ischemic and valvular heart disease. In this study, we hypothesized that CT-1 induces endothelial cell angiogenesis and that the ADMA/DDAH ...
Zhen Zhong Zheng+3 more
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Numerical experiments on the accuracy of ENO and modified ENO schemes [PDF]
Further numerical experiments are made assessing an accuracy degeneracy phenomena. A modified essentially non-oscillatory (ENO) scheme is proposed, which recovers the correct order of accuracy for all the test problems with smooth initial conditions and gives comparable results with the original ENO schemes for discontinuous problems.
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BackgroundEndothelial dysfunction has been suggested as a possible causal link between hyperglycemia and microvascular complications in diabetes mellitus. The effect of metformin on endothelial progenitor cells (EPCs) is still unclear.
Jiawen Yu+5 more
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En el municipio de El Carmen de Viboral, Antioquia, la cuenca de la quebrada La Cimarronas y sus afluentes Los Andes y La Madera son las principales fuentes de abastecimiento del acueducto de la localidad.
Yimmy Montoya-Moreno+3 more
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