Results 41 to 50 of about 214,822 (255)

Osteogenic actions of the osteogenic growth peptide on bovine marrow mesenchymal stromal cells in culture

open access: yesVeterinární Medicína, 2008
The osteogenic growth peptide (OGP) regulates the differentiation of marrow mesenchymal stem cells derived from human and rodent cell lines into osteoblasts.
H.B. Zhu   +7 more
doaj   +1 more source

Effects of resveratrol on eNOS in the endothelium and the perivascular adipose tissue

open access: yesAnnals of the New York Academy of Sciences, 2017
Under physiological conditions, nitric oxide (NO) is produced in the vasculature mainly by the endothelial NO synthase (eNOS). Experiments using gene‐disrupted mice have demonstrated that eNOS has antihypertensive, antithrombotic, and antiatherosclerotic
N. Xia, U. Förstermann, Huige Li
semanticscholar   +1 more source

eNOS transfection of adipose-derived stem cells yields bioactive nitric oxide production and improved results in vascular tissue engineering. [PDF]

open access: yes, 2015
This study evaluates the durability of a novel tissue engineered blood vessel (TEBV) created by seeding a natural vascular tissue scaffold (decellularized human saphenous vein allograft) with autologous adipose-derived stem cells (ASC) differentiated ...
Bagameri, Gabor   +10 more
core   +2 more sources

Effects of novel muscarinic M3 receptor ligand C1213 in pulmonary arterial hypertension models. [PDF]

open access: yes, 2016
Pulmonary hypertension (PH) is a complex disease comprising a pathologic remodeling and thickening of the pulmonary vessels causing an after load on the right heart ventricle that can result in ventricular failure. Triggered by oxidative stress, episodes
Ahmed, Mohamed   +5 more
core   +2 more sources

Uric acid enhances PKC-dependent eNOS phosphorylation and mediates cellular ER stress: A mechanism for uric acid-induced endothelial dysfunction

open access: yesInternational Journal of Molecular Medicine, 2016
The mechanism by which hyperuricemia induced-endothelial dysfunction contributes to cardiovascular diseases (CVDs) is not yet fully understood. In the present study, we used uric acid (UA) to trigger endothelial dysfunction in cultured endothelial cells,
Peng Li   +4 more
semanticscholar   +1 more source

Examining the role of insulin in the regulation of cardiovascular health [PDF]

open access: yes, 2013
A substantial body of evidence has reported that insulin has direct actions on the cardiovascular system independent of its systemic effects on plasma glucose or lipids.
Salt, Ian P.
core   +1 more source

eNOS/iNOS and endoplasmic reticulum stress-induced apoptosis in the placentas of patients with preeclampsia

open access: yesJournal of Human Hypertension, 2016
Disruption of nitric oxide pathway and endoplasmic reticulum (ER) stress had been observed in preeclampsia (PE). However, the correlation and overall detailed expression profiles of ER stress-related markers and endothelial nitric oxide synthase ...
L. Du   +5 more
semanticscholar   +1 more source

Pathophysiological Role of Caveolae in Hypertension [PDF]

open access: yes, 2019
Caveolae, flask-shaped cholesterol-, and glycosphingolipid-rich membrane microdomains, contain caveolin 1, 2, 3 and several structural proteins, in particular Cavin 1-4, EHD2, pacsin2, and dynamin 2.
Daumke, Oliver   +4 more
core   +2 more sources

S-allylcysteine Improves Blood Flow Recovery and Prevents Ischemic Injury by Augmenting Neovasculogenesis. [PDF]

open access: yes, 2017
Studies suggest that a low level of circulating human endothelial progenitor cells (EPCs) is a risk factor for ischemic injury and coronary artery disease (CAD). Consumption of S-allylcysteine (SAC) is known to prevent CAD.
Chao, Che-Yi   +7 more
core   +1 more source

Phenolic metabolites of anthocyanins modulate mechanisms of endothelial function [PDF]

open access: yes, 2015
Anthocyanins are reported to have vascular bioactivity, however their mechanisms of action are largely unknown. Evidence suggests that anthocyanins modulate endothelial function, potentially by increasing nitric oxide (NO) synthesis, or enhancing NO ...
Cassidy, Aedin   +4 more
core   +1 more source

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