Results 41 to 50 of about 100,569 (330)

eNOS Function and Dysfunction in the Penis

open access: yesExperimental Biology and Medicine, 2006
Endothelial nitric oxide (NO) synthase (eNOS) has an indispensable role in the erectile response. In the penis, eNOS activity and endothelial NO bioavailability are regulated by multiple post-translatlonal molecular mechanisms, such as eNOS phosphorylation, eNOS interaction with regulatory proteins and contractile pathways, and actions of reactive ...
Arthur L. Burnett, Biljana Musicki
openaire   +3 more sources

Central role of eNOS in the maintenance of endothelial homeostasis.

open access: yesAntioxidants and Redox Signaling, 2015
SIGNIFICANCE Disruption of endothelial function is considered a key event in the development and progression of atherosclerosis. Endothelial nitric oxide synthase (eNOS) is a central regulator of cellular function that is important to maintain ...
C. Heiss, A. Rodriguez-Mateos, M. Kelm
semanticscholar   +1 more source

Say NO to ROS: Their Roles in Embryonic Heart Development and Pathogenesis of Congenital Heart Defects in Maternal Diabetes

open access: yesAntioxidants, 2019
Congenital heart defects (CHDs) are the most prevalent and serious birth defect, occurring in 1% of all live births. Pregestational maternal diabetes is a known risk factor for the development of CHDs, elevating the risk in the child by more than four ...
Anish Engineer   +3 more
doaj   +1 more source

Plasma concentrations of endothelial nitric oxide synthase (enos) after different physical exercises

open access: yesБюллетень сибирской медицины, 2017
The purpose of the study is to evaluate the effect of dynamic and static exercises on eNOS concentrations in the blood plasma of athletes who do cyclic and strength kind of sports, as well as in men, who are not involved in any sports.Materials and ...
E. Yu. Dyakova   +5 more
doaj   +1 more source

Partial eNOS deficiency causes spontaneous thrombotic cerebral infarction, amyloid angiopathy and cognitive impairment

open access: yesMolecular Neurodegeneration, 2015
BackgroundCerebral infarction due to thrombosis leads to the most common type of stroke and a likely cause of age-related cognitive decline and dementia.
Xing Tan   +9 more
semanticscholar   +1 more source

Purinergic glio-endothelial coupling during neuronal activity: role of P2Y1 receptors and eNOS in functional hyperemia in the mouse somatosensory cortex.

open access: yesAmerican Journal of Physiology. Heart and Circulatory Physiology, 2015
Impairment of moment-to-moment adjustment of cerebral blood flow (CBF) via neurovascular coupling is thought to play a critical role in the genesis of cognitive impairment associated with aging and pathological conditions associated with accelerated ...
Peter Toth   +12 more
semanticscholar   +1 more source

Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue   +7 more
wiley   +1 more source

The efficacy of nitric oxide in stroke (ENOS) trial – where do we stand in Romania? [PDF]

open access: yesRomanian Journal of Neurology, 2012
Introduction. Romania ranks third worldwide for stroke mortality. Although high blood pressure (BP) is a major risk factor for stroke incidence and determinant of outcome, the management of BP in acute stroke remains undefined. The present study assesses
Szocs Ildiko   +7 more
doaj   +1 more source

Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?

open access: yesBritish Journal of Pharmacology, EarlyView., 2023
Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley   +1 more source

Genetic Susceptibility to Retinopathy of Prematurity: A Paradigm for Preterm Disease Traits

open access: yesDelhi Journal of Ophthalmology, 2014
Retinopathy of prematurity (ROP) is a vasoproliferative retinal disorder in premature infants that can lead to blindness and the incidence is increasing with increased survival of infants born at very early gestational age and low birth weight.
Manzoor Ahmad Malik   +3 more
doaj   +1 more source

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