Results 51 to 60 of about 100,569 (330)

Bioengineering Strategies for Treating Neointimal Hyperplasia in Peripheral Vasculature: Innovations and Challenges

open access: yesAdvanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
This review highlights emerging bioengineering strategies for treating neointimal hyperplasia in the peripheral vasculature, focusing on approaches that promote re‐endothelialization, modulate smooth muscle cell phenotype, reduce inflammation, mitigate oxidative stress, and optimize biomechanical compliance.
Nikita Wilson John   +5 more
wiley   +1 more source

REALITIES AND PROSPECTS FOR PHARMACOLOGICAL CORRECTION OF «ADMA-ENOS"-ASSOCIATED WAYS IN PREECLAMPSIA

open access: yesРациональная фармакотерапия в кардиологии, 2016
Methylated analogs of L-arginine - asymmetric dimetilarginin (ADMA) and monometilarginin (L-NMMA) - are endogenous inhibitors of endothelial NO-synthase (eNOS). ADMA level in maternal plasma is increased in women with preeclampsia. The high level of ADMA
M. V. Pokrovsky   +12 more
doaj   +1 more source

Bioengineering a Patient‐Derived Vascularized Lung Tumor‐on‐Chip Model to Decipher Immunomodulation by the Endothelium

open access: yesAdvanced Healthcare Materials, EarlyView.
Most in vitro cancer models lack cellular diversity, functional complexity, and clinical relevance. This work highlights the generation of an innovative dynamic tetraculture with autologous patient‐derived cells within a vascularized tumor‐on‐chip, as well as the recapitulation of endothelial anergy features induced by the tumor microenvironment ...
Christine Lansche   +16 more
wiley   +1 more source

Stranded Marine Mammals on the South-Central Coast of Peru during El Niño 1997-98

open access: yesRevista Peruana de Biología
During the 1997-98 El Niño event, an assessment of marine mammal strandings was conducted from August 1997 to April 1998 between 15°22' and 15°27' S. This assessment encompassed 30.4 km of coastline, distributed in seven sectors located along the borders
Manuel Apaza
doaj   +1 more source

Targeting eNOS in Pancreatic Cancer [PDF]

open access: yesCancer Research, 2012
Abstract Mortality from pancreatic ductal adenocarcinoma cancer (PDAC) is among the highest of any cancer and frontline therapy has changed little in years. Activation of endothelial nitric oxide synthase (eNOS, NOS3, or NOS III) has been implicated recently in the pathogenesis of PDACs.
Christopher M. Counter   +14 more
openaire   +2 more sources

eNOS Genetic Polymorphisms and Cancer Risk

open access: yesMedicine, 2015
The association between endothelial nitric oxide synthase (eNOS) polymorphisms (intron 4a/b, -786T>C and 894G>T) and cancer risk remains elusive.
Xueren Gao   +4 more
semanticscholar   +1 more source

Enhancing the Pharmacokinetics of Aptamers: Targeting AXL In Vivo Using a Bottlebrush Polymer‐Conjugated Aptamer

open access: yesAdvanced Healthcare Materials, EarlyView.
A phosphodiester‐backboned bottlebrush polymer (pacDNA) engineered for aptamer delivery is presented. This design enhances aptamer stability, plasma pharmacokinetics, and target engagement in vivo. In AXL‐driven cancer models, pacDNA inhibits AXL signaling and reduces tumor growth, highlighting the promise of precision polymer scaffolds in aptamer ...
Tingyu Sun   +13 more
wiley   +1 more source

Association between Genetic Variants of Nitric Oxide/cGMP Pathway and Susceptibility to Hypertension in Kermanshah Province

open access: yesJournal of Mazandaran University of Medical Sciences, 2023
Background and purpose: Hypertension is a global health challenge due to its high prevalence and increased risk of cardiovascular disease. It is a multifactorial disease in which both genetic and environmental factors are involved.
Parham Nejati   +6 more
doaj  

Análisis del impacto del fenómeno del Monzón en la producción agrícola de la India

open access: yesJournal de Ciencias Sociales, 2016
La producción agrícola de la India se ve afectada por el fenómeno del Monzón, que significa estación, lo cual explica su aplicación a los cambios estacionales a gran escala del régimen de los vientos y la alternancia de un período seco y otro húmedo. El
María Guillermina Diaz
doaj   +1 more source

Stability Properties of the ENO Method [PDF]

open access: yes, 2016
To appear in Handbook of Numerical Methods for Hyperbolic ...
openaire   +3 more sources

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