Results 71 to 80 of about 40,526 (207)

Precision mRNA Delivery via Ultrasound‐Controlled Release Perfluorocarbon Emulsions: An Innovative Ultrasound Theranostic Strategy with 19F MRI Feasibility

Small, EarlyView.
A key challenge in advancing messenger RNA (mRNA) therapeutics in cardiovascular diseases lies in achieving controlled release at the precise site within the vasculature. This study presents the development of perfluorocarbon nanodroplets with exceptional theranostic potential, enabling real‐time tracking through ultrasound and fluorine‐19 (19F ...
Haikun Liu, Mark Louis P. Vidallon, Yuyang Song, Aidan P. G. Walsh, Henry Gordon, Shulei Ren, Pengkai Shi, Bangyan Xu, Mitchell J. Moon, Sylvain Trépout, Rico F. Tabor, Alexis I. Bishop, Ulrich Flögel, Karlheinz Peter, Xiaowei Wang   +14 more
wiley   +1 more source

A randomized clinical trial on the anti-tumoral effects of low molecular weight heparin in the treatment of esophageal cancer [PDF]

, 2019
The current treatment approaches for esophageal cancer are associated with poor survival, and there are ongoing efforts to find new and more effective therapeutic strategies.
Avan, Amir, Fanipakdel, Azar, Ferns, Gordon, Gholami, Arezoo, Hosseini, Sare, Javadinia, Seyed Alireza, Kermani, Ali Taghizadeh, Mashhad, Mona Joudi, Rezayat, Kambiz Akhavan, Zardadi, Mahdi   +9 more
core   +1 more source

Perspectives of Healthcare Professionals, Patients and Family Members on Managing Regular Medications Across the Perioperative Pathway: An Exploratory Qualitative Study

Journal of Advanced Nursing, EarlyView.
ABSTRACT Aim To explore healthcare professionals', patients', and family members' experiences of managing regular medications across the perioperative pathway in a specialist cancer hospital in Melbourne. Design An exploratory qualitative study using a descriptive‐interpretive approach.
Atefeh Mehrabifar, Elizabeth Manias, Thomas E. Poulton, Bernhard Riedel, Janelle Penno, Patricia Nicholson   +5 more
wiley   +1 more source

Extensive Pulmonary Embolism in late pregnancy associated with Anticardiolipin Antibodies [PDF]

, 2004
The leading cause of morbidity and mortality during pregnancy and the puerperium is venous thromboembolism. Though uncommon, the risk is five times higher in a pregnant woman than in a non-pregnant woman of similar age.1,2 In pregnancy, all three ...
Brincat, Mark P., Buhagiar, Louis, Formosa, Mark, Galea, David P., Kunovski, Goce, Samuel, Anthony   +5 more
core  

Fibrinolysis or Primary PCI in ST-Segment Elevation Myocardial Infarction [PDF]

, 2013
BACKGROUNDIt is not known whether prehospital fibrinolysis, coupled with timely coronary angiography, provides a clinical outcome similar to that with primary percutaneous coronary intervention (PCI) early after acute ST-segment elevation myocardial ...
Armstrong, Paul W., Arntz, Hans-Richard, Bluhmki, Erich, Bogaerts, Kris, Carvalho, Antonio C., Danays, Thierry, Fresco, Claudio, Gershlick, Anthony H., Goldstein, Patrick, Grajek, Stefan, Halvorsen, Sigrun, Huber, Kurt, Lambert, Yves, Nanas, John, Ostojic, Miodrag, Regelin, Anne, Rosell Ortiz, Fernando, STREAM Investigative Team, Sulimov, Vitaly, Van de Werf, Frans, Vandenberghe, Katleen, Welsh, Robert C., Wilcox, Robert   +22 more
core   +1 more source

Low‐Molecular‐Weight Heparin for Adult ICU Patients Who Require Thromboprophylaxis: Protocol for the INCEPT‐Thromboprophylaxis Platform Trial Domain

Acta Anaesthesiologica Scandinavica, Volume 70, Issue 3, March 2026.
ABSTRACT Background Low‐molecular‐weight heparin (LMWH) is recommended for thromboprophylaxis in adult intensive care unit (ICU) patients. Despite its widespread use, there is insufficient evidence on the optimal dose, and there appears to be practice variation.
Ruben Eck, Anders Granholm, Aske Tøgern, Aksel Karl Georg Jensen, Sandra Jonmarker, Fredrik Sjövall, Karina Meijer, Maria Cronhjort, Morten Hylander Møller, Anders Perner, Frederik Keus   +10 more
wiley   +1 more source

Thromboembolism After Intramedullary Nailing for Metastatic Bone Lesions. [PDF]

, 2015
BACKGROUND: The risk of venous thromboembolism (VTE) in patients undergoing intramedullary nailing for skeletal metastatic disease is currently undefined.
Abraham, John A, Geller, David S, Greenbaum, Simon, Lee, Alan, Maltenfort, PhD, Mitchell, Merli, Geno J, Ready, John, Shallop, Brandon, Starks, Alexandria   +8 more
core   +2 more sources

Safety and Efficacy of Anticoagulation Therapy in Paediatric Patients With Solid Tumours or Lymphomas at Risk of Thrombocytopenia: A Retrospective Study

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background Patients with solid tumours or lymphomas have an increased risk of thromboembolism (TE) and thrombocytopenia. Evidence‐based strategies for anticoagulation therapy (ACT) for patients with thrombocytopenia are limited. We examined the impact of thrombocytopenia on ACT administration and bleeding incidence in children with solid ...
Andrés Felipe Fajardo, Katherine Talpin, Bishal Harry, Uma H. Athale, Anthony K. C. Chan, Mihir D. Bhatt   +5 more
wiley   +1 more source

Enoxaparin utilization evaluation in inpatients with or at risk of thromboembolic disorders: A one-year, single-centered, retrospective Study

Pharmaceutical and Biomedical Research, 2016
The aim of this study was evaluation of enoxaparin utilization in hospitalized patients who had received enoxaparin either for prophylaxis or for treatment of thromboembolic disorders.
Shahram Ala, Gohar Eslami, Atieh sayftabar   +2 more
doaj  

Preoperative Cytopenia in Patients Affected by High‐Risk Neuroblastoma: Just a Matter of Platelets?

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Background and Aims In patients affected by high‐risk neuroblastoma (HR‐NB), complete macroscopic resection (CMR) is associated with better outcomes. These patients are often cytopenic due to intensive induction regimens. The aim of the present study is to assess the impact of preoperative cytopenia on surgical outcome in patients with HR‐NB ...
Giorgio Persano, Valerio Voglino, Federico Beati, Cristina Martucci, Chiara Grimaldi, Francesca Del Bufalo, Annalisa Serra, Francesco Fabozzi, Carmen Malaspina, Pier Luigi Di Paolo, Gian Luigi Natali, Simone Reali, Maria Antonietta De Ioris, Alessandro Crocoli   +13 more
wiley   +1 more source