Results 91 to 100 of about 1,474,815 (298)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Challenging the role of implicit processes in probabilistic category learning [PDF]

open access: yes, 2007
Considerable interest in the hypothesis that different cognitive tasks recruit qualitatively distinct processing systems has led to the proposal of separate explicit (declarative) and implicit (procedural) systems.
Lagnado, DA, Shanks, DR, Newell, BR
core  

A higher-dimensional categorical perspective on 2-crossed modules

open access: yesDemonstratio Mathematica
In this study, we will express the 2-crossed module of groups from a higher-dimensional categorical perspective. According to simplicial homotopy theory, a 2-crossed module is the Moore complex of a 2-truncated simplicial group.
Özel Emre   +2 more
doaj   +1 more source

Building 1D lattice models with $G$-graded fusion category

open access: yesSciPost Physics
We construct a family of one-dimensional (1D) quantum lattice models based on $G$-graded unitary fusion category $\mathcal{C}_G$. This family realize an interpolation between the anyon-chain models and edge models of 2D symmetry-protected topological ...
Shang-Qiang Ning, Bin-Bin Mao, Chenjie Wang
doaj   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

A role for the developing lexicon in phonetic category acquisition [PDF]

open access: yes, 2013
Infants learn to segment words from fluent speech during the same period as they learn native language phonetic categories, yet accounts of phonetic category acquisition typically ignore information about the words in which sounds appear.
Morgan, James L.   +3 more
core  

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

turtles-contigs-enriched-from-taxa.fasta

open access: yes, 2012
FASTA file of contigs assembled from raw reads generated by sequencing enriched libraries of several reptile ...
Brant C. Faircloth (143432)   +5 more
core   +1 more source

Rigidity and exotic models for the K-local stable homotopy category [PDF]

open access: yes, 2007
Can the model structure of a stable model category be recovered from the triangulated structure of its homotopy category? This paper introduces a new positive example for this, namely the K-local stable homotopy at the prime 2.
Roitzheim, C., Roitzheim, Constanze
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

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