Results 81 to 90 of about 1,474,815 (298)

The Grothendieck Construction in Enriched, Internal and ∞-Category Theory [PDF]

open access: yes, 2019
Thesis (Ph.D.)--University of Washington, 2019The Grothendieck construction takes a prestack (or pseudofunctor) B^op → Cat and returns a cartesian fibration over B. Classically, this construction works for categories with sets of morphisms.
Wong, Liang Ze
core  

Mixed Relations as Enriched Semiringal Categories

open access: yesJ. Univers. Comput. Sci., 2000
JUCS - Journal of Universal Computer Science Volume Nr.
Grosu,Radu   +2 more
openaire   +2 more sources

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

A mathematical theory of gapless edges of 2d topological orders. Part I

open access: yesJournal of High Energy Physics, 2020
This is the first part of a two-part work on a unified mathematical theory of gapped and gapless edges of 2d topological orders. We analyze all the possible observables on the 1+1D world sheet of a chiral gapless edge of a 2d topological order, and show ...
Liang Kong, Hao Zheng
doaj   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Enriched model categories and presheaf categories

open access: yes, 2011
We collect in one place a variety of known and folklore results in enriched model category theory and add a few new twists. The central theme is a general procedure for constructing a Quillen adjunction, often a Quillen equivalence, between a given V-model category and a category of enriched presheaves in V, where V is any good enriching category.
Guillou, Bertrand J., May, J. Peter
openaire   +3 more sources

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Weak n-Ary Relational Products in Allegories

open access: yesAxioms, 2014
Allegories are enriched categories generalizing a category of sets and binary relations. Accordingly, relational products in an allegory can be viewed as a generalization of Cartesian products.
Bartosz Zieliński, Paweł Maślanka
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

A Model 2-Category of Enriched Combinatorial Premodel Categories

open access: yes, 2019
Quillen equivalences induce equivalences of homotopy theories and therefore form a natural choice for the "weak equivalences" between model categories. In [21], Hovey asked whether the 2-category Mod of model categories has a "model 2-category structure"
Barton, Reid William
core   +4 more sources

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