Results 111 to 120 of about 1,477,961 (298)
Enriched Reedy categories [PDF]
Proceedings of the American Mathematical Society, 2008 We define the notion of an enriched Reedy category, and show that if A is a C-Reedy category for some symmetric monoidal model category C and M is a C-model category, the category of C-functors and C-natural transformations from A to M is again a model category.
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Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Barr’s embedding theorem for enriched categories
Journal of Pure and Applied Algebra, 2011 11 ...
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Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Univalent Enriched Categories and the Enriched Rezk Completion
Logical Methods in Computer ScienceEnriched categories are categories whose sets of morphisms are enriched with extra structure. Such categories play a prominent role in the study of higher categories, homotopy theory, and the semantics of programming languages. In this paper, we study univalent enriched categories.
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A Lower Bound for the LS Category of a Formal Elliptic Space [PDF]
, 2005 We give a lower bound for the LS category of a formal elliptic space in terms of its rational cohomology.
Kotani, Yasusuke, Yamaguchi, Toshihiro
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Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Using deep learning for short text understanding
Journal of Big Data, 2017 Classifying short texts to one category or clustering semantically related texts is challenging, and the importance of both is growing due to the rise of microblogging platforms, digital news feeds, and the like.
Justin Zhan, Binay Dahal
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Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Enriched monoidal categories I: Centers
Quantum TopologyThis work is the first one in a series, in which we develop a mathematical theory of enriched (braided) monoidal categories and their representations. In this work, we introduce the notion of the E_{0} -center (
Liang Kong +3 more
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