Results 91 to 100 of about 7,106,216 (352)
The power of microRNA regulation—insights into immunity and metabolism
FEBS Letters, EarlyView.MicroRNAs are emerging as crucial regulators at the intersection of metabolism and immunity. This review examines how miRNAs coordinate glucose and lipid metabolism while simultaneously modulating T‐cell development and immune responses. Moreover, it highlights how cutting‐edge artificial intelligence applications can identify miRNA biomarkers ...
Stefania Oliveto +2 more
wiley +1 more source
Chemical enrichment of stars due to accretion from ISM during the Galaxy's assembly [PDF]
, 2016 Using the Eris zoom-in cosmological simulation of assembly of a Milky Way analog, we study chemical enrichment of stars due to accretion of metal-enriched gas from the interstellar medium during the Galaxy's development. We consider metal-poor and old stars in both Galactic halo and bulge and make use of stellar orbits, gas density and metallicity ...
arxiv +1 more source
PeerJ, 2018 Background The enriched environment (EE) is a laboratory housing model that emerged from efforts to minimize the impact of environmental conditions on laboratory animals.
M. Marcon +5 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley +1 more source
The impact of changeability of enriched environment on exploration in rats
Behavioural Processes, 2019 Although the positive effect of environmental enrichment on animals' cognitive capacities is well-known, it remains unclear what role changeability plays in this context. Our study aims to analyse the impact of environmental changeability on the level of exploration and the rate of habituation to novelty.
Klaudia Modlinska +2 more
openaire +3 more sources
Environmental stimuli shape microglial plasticity in glioma
eLife, 2017 In glioma, microglia and infiltrating macrophages are exposed to factors that force them to produce cytokines and chemokines, which contribute to tumor growth and to maintaining a pro-tumorigenic, immunosuppressed microenvironment.
Stefano Garofalo +20 more
doaj +1 more source
Journal of Neuroscience, 2018 Chondroitin sulfate proteoglycan (CSPG) is a candidate regulator of embryonic neurogenesis. The aim of this study was to specify the functional significance of CSPG in adult hippocampal neurogenesis using male mice. Here, we showed that neural stem cells
J. Yamada +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Urine is a rich source of biomarkers for cancer detection. Tumor‐derived material is released into the bloodstream and transported to the urine. Urine can easily be collected from individuals, allowing non‐invasive cancer detection. This review discusses the rationale behind urine‐based cancer detection and its potential for cancer diagnostics ...
Birgit M. M. Wever +1 more
wiley +1 more source
Possible Population III Remnants at Redshift 3.5 [PDF]
, 2015 The first stars, known as Population III (PopIII), produced the first heavy elements, thereby enriching their surrounding pristine gas. Previous detections of metals in intergalactic gas clouds, however, find a heavy element enrichment larger than $1/1000$ times that of the solar environment, higher than expected for PopIII remnants.
arxiv +1 more source
Neural Regeneration Research, 2019 Cerebral ischemia activates an endogenous repair program that induces plastic changes in neurons. In this study, we investigated the effects of environmental enrichment on spatial learning and memory as well as on synaptic remodeling in a mouse model of ...
Chuan-Jie Wang +4 more
semanticscholar +1 more source