Results 111 to 120 of about 996,291 (283)

Characterizing epithelial‐mesenchymal transition‐linked heterogeneity in breast cancer circulating tumor cells at a single‐cell level

Molecular Oncology, EarlyView.
In over 50% of non‐metastatic breast cancer patients, circulating tumor cells (CTCs) along the whole epithelial‐mesenchymal transition spectrum are detected. Total CTC number and individual phenotypes relate to aggressive disease characteristics, including lymph node involvement and higher tumor proliferation. At the single‐cell level, mesenchymal CTCs
Justyna Topa, Julia Richert, Tomasz Stokowy, Alicja Staśczak, Mariusz Szajewski, Maciej Ciesielski, Petra M. Grešner, Bartłomiej Tomasik, Łukasz Arcimowicz, Agnieszka Stankiewicz, Grażyna Suchodolska, Elżbieta Senkus, Wiesław Kruszewski, Anna J. Żaczek, Aleksandra Markiewicz   +14 more
wiley   +1 more source

Enriched environment and physical activity reverse astrogliodegeneration in the hippocampus of AD transgenic mice [PDF]

, 2013
José J. Rodrı́guez, Slavica Terzieva, Markel Olabarria, R. Lanza, Alexei Verkhratsky   +4 more
openalex   +1 more source

Replication Data for: The gender gap in political interest: heritability, gendered political socialization, and the enriched environment hypothesis

, 2023
Mathilde M. van Ditmars, Aleksander Ksiazkiewicz   +1 more
openalex   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Environmental Enrichment Upregulates Striatal Synaptic Vesicle-Associated Proteins and Improves Motor Function

Frontiers in Neurology, 2018
Environmental enrichment (EE) is a therapeutic paradigm that consists of complex combinations of physical, cognitive, and social stimuli. The mechanisms underlying EE-mediated synaptic plasticity have yet to be fully elucidated.
Suk-Young Song, Suk-Young Song, Minji Chae, Minji Chae, Ji Hea Yu, Min Young Lee, Soonil Pyo, Soonil Pyo, Yoon-Kyum Shin, Yoon-Kyum Shin, Ahreum Baek, Ahreum Baek, Jung-Won Park, Eun Sook Park, Ja Young Choi, Ja Young Choi, Sung-Rae Cho, Sung-Rae Cho, Sung-Rae Cho, Sung-Rae Cho   +19 more
doaj   +1 more source

Effect of breed suitability, system design and management on welfare & performance in traditional & organic poultrymeat (OF0153) [PDF]

, 2002
Background Over the past fifty years broiler production accounted for almost all of the meat chickens produced in the UK. As a result, only broiler hybrids were available for use by UK producers, and these were not thought to be suited for use in some ...
Gordon, Mrs Sue
core  

Plasma extrachromosomal circular DNA as a biomarker in EGFR‐targeted therapy of non‐small cell lung cancer

Molecular Oncology, EarlyView.
Detection of extrachromosomal circular DNA (eccDNA) in plasma samples from EGFR‐mutated non‐small cell lung cancer patients. Plasma was collected before and during treatment with the EGFR‐tyrosine kinase inhibitor osimertinib. Plasma eccDNA was detected in all cancer samples, and the presence of the EGFR gene on eccDNA serves as a potential biomarker ...
Simone Stensgaard, Sarmad Mehmood, Eva Boysen Fynboe Ebert, Peter Meldgaard, Anindya Dutta, Boe S. Sorensen   +5 more
wiley   +1 more source

Is environmental enrichment effective in modulating autophagy markers in the brain exposed to adverse conditions? A systematic review

Frontiers in Cellular Neuroscience
Autophagy is a key regulator of cellular homeostasis and neuronal survival, particularly under adverse physiological conditions. Environmental enrichment (EE), a non-pharmacological intervention providing enhanced sensory, cognitive, and motor ...
Clarice Beatriz Gonçalves Silva, Matheus Santos de Sousa Fernandes, Matheus Santos de Sousa Fernandes, Debora Dantas Nucci Cerqueira, Debora Dantas Nucci Cerqueira, Gabriela Carvalho Jurema Santos, Fatma Hilal Yagin, Yalin Aygun, Georgian Badicu, Fabiana S. Evangelista, Pablo Prieto-González, Fabrício Oliveira Souto, Fabrício Oliveira Souto, Ashit Kumar Dutta, Sameer Badri Al-Mhanna, Sameer Badri Al-Mhanna, Sameer Badri Al-Mhanna, Abedelmalek Kalefh Tabnjh, Abedelmalek Kalefh Tabnjh, Abedelmalek Kalefh Tabnjh   +19 more
doaj   +1 more source

Soil domestication by rice cultivation results in plant-soil feedback through shifts in soil microbiota. [PDF]

, 2019
BackgroundSoils are a key component of agricultural productivity, and soil microbiota determine the availability of many essential plant nutrients.
Edwards, Joseph, Kilmer, John, Liechty, Zachary, Nguyen, Bao, Ni, Jiadong, Phillips, Gregory, Santos-Medellín, Christian, Sundaresan, Venkatesan, Veliz, Esteban   +8 more
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source