Results 81 to 90 of about 1,026,955 (282)

Suppelmentary Figure S5 from Enriching the Housing Environment for Mice Enhances Their NK Cell Antitumor Immunity via Sympathetic Nerve–Dependent Regulation of NKG2D and CCR5 [PDF]

open access: gold, 2023
Yanfang Song   +10 more
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

CD4+ T Cells Have a Permissive Effect on Enriched Environment-Induced Hippocampus Synaptic Plasticity

open access: yesFrontiers in Synaptic Neuroscience, 2018
Living in an enriched environment (EE) benefits health by acting synergistically on various biological systems including the immune and the central nervous systems.
Hadi Zarif   +11 more
doaj   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

The activated newborn neurons participate in enriched environment induced improvement of locomotor function in APP/PS1 mice

open access: yesBrain and Behavior, 2019
Introduction Alzheimer's disease (AD) is an age‐related neurodegenerative disorder. One of the pathological features of AD is neuronal loss in brain regions associated with cognition, particularly the hippocampus.
Hualong Wang   +6 more
doaj   +1 more source

Response threshold to aversive stimuli in stimulated early protein-malnourished rats

open access: yesBrazilian Journal of Medical and Biological Research, 1997
Two animal models of pain were used to study the effects of short-term protein malnutrition and environmental stimulation on the response threshold to aversive stimuli. Eighty male Wistar rats were used. Half of the pups were submitted to malnutrition by
L.F. Rocinholi   +2 more
doaj   +1 more source

Natural variation in abiotic stress responsive gene expression and local adaptation to climate in Arabidopsis thaliana. [PDF]

open access: yes, 2014
Gene expression varies widely in natural populations, yet the proximate and ultimate causes of this variation are poorly known. Understanding how variation in gene expression affects abiotic stress tolerance, fitness, and adaptation is central to the ...
Des Marais, David L   +7 more
core   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

The effects of environmental enrichment on biochemical and metric parameters of aged rats

open access: yesBioscience Journal, 2015
The enriched environment (EE) is a promoter of physical activity, by its characteristics such as ample room for movement and exploration, presence of wheels, tunnels and toys.
Thiago Aparecido Vieira   +6 more
doaj   +1 more source

Omega-3 enriched chick diet reduces the foraging areas of breeders in two closely related shearwaters from contrasting marine environments [PDF]

open access: bronze, 2023
Sara H. Santos   +11 more
openalex   +1 more source

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