Results 91 to 100 of about 1,344,829 (308)

Enrichment plots from Gene Set Enrichment Analysis (GSEA).

open access: yes, 2021
Enrichment plots from Gene Set Enrichment Analysis (GSEA).
Yideng Huang (10176209)   +6 more
core   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Internal Enriched Categories

open access: yesApplied Categorical Structures, 2022
AbstractWe introduce the theory of enrichment over an internal monoidal category as a common generalization of both the standard theories of enriched and internal categories. Then, we contextualize the new notion by comparing it to another known generalization of enrichment: that of enrichment for indexed categories.
openaire   +3 more sources

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

open access: yesFEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise   +5 more
wiley   +1 more source

Research on lower limit of TOC content for hydrocarbon expulsion and shale oil enrichment using carbon mass balance method: a case study of shale of lower submember of the third member of Paleogene Shahejie Formation in Jiyang Depression

open access: yesShiyou shiyan dizhi
Currently, research methods for determining the lower limit of total organic carbon (TOC) content for hydrocarbon expulsion from source rocks and for shale oil enrichment vary, and the determined lower limit values show significant differences.
Youshu BAO   +5 more
doaj   +1 more source

Skew-Enriched Categories [PDF]

open access: yesApplied Categorical Structures, 2017
This paper introduces a skew variant of the notion of enriched category, suitable for enrichment over a skew-monoidal category, the main novelty of which is that the elements of the enriched hom-objects need not be in bijection with the morphisms of the underlying category.
openaire   +4 more sources

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

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