Results 101 to 110 of about 1,292,580 (305)

joelbader/regulon-enrichment: First Release

open access: yes, 2017
<p>This is the first release of our code supporting our manuscript: "Gene enrichment analysis reveals major regulators of <em>Mycobacterium tuberculosis</em> gene expression in two models of antibiotic tolerance".</p ...
Will Matern, Will Matern (8260089)
core   +1 more source

‘Guide and Prejudice’— How Argonautes recognize targets across domains of life

open access: yesFEBS Letters, EarlyView.
Argonaute proteins use short nucleic‐acid guides to locate and regulate specific targets across all domains of life. Despite striking diversity—from human gene silencing to bacterial immune defence—all Argonautes share a conserved three‐stage recognition logic: guide‐directed sampling, progressive target pairing with a conformational checkpoint and ...
Jack P. K. Bravo
wiley   +1 more source

Identifying diatom indicator species of nutrient enrichment: An in situ nutrient enrichment experiment in subtropical upland streams

open access: yes, 2020
Nutrients are a fundamental determinant of broad scale patterns in the benthic algal community of stream ecosystems. Excessive inputs of nutrients such as nitrogen and phosphorus into upland streams may result in significant impacts on benthic algal ...
Hadwen, Wade L   +2 more
core   +1 more source

Research on lower limit of TOC content for hydrocarbon expulsion and shale oil enrichment using carbon mass balance method: a case study of shale of lower submember of the third member of Paleogene Shahejie Formation in Jiyang Depression

open access: yesShiyou shiyan dizhi
Currently, research methods for determining the lower limit of total organic carbon (TOC) content for hydrocarbon expulsion from source rocks and for shale oil enrichment vary, and the determined lower limit values show significant differences.
Youshu BAO   +5 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Time-independent hybrid enrichment for finite element solution of transient conduction–radiation in diffusive grey media [PDF]

open access: yes, 2013
We investigate the effectiveness of the partition-of-unity finite element method for transient conduction–radiation problems in diffusive grey media. The governing equations consist of a semi-linear transient heat equation for the temperature ?eld and a ...
Mohamed, M.S.   +7 more
core   +1 more source

A Study on Hydrocarbon Generation Capacity of Graptolite in Marine Hydrocarbon Source Rocks in Southern China

open access: yesYankuang ceshi, 2017
The common development of graptolite in marine shale of Southern China has a close relationship with the formation of marine shale gas, but whether graptolite has hydrocarbon generating ability of shale gas has not been directly confirmed by relevant ...
WANG Qin   +4 more
doaj   +1 more source

Leucine‐rich glioma inactivated 1 (LGI1) is a ganglioside‐binding protein

open access: yesFEBS Letters, EarlyView.
Neuronal hyperexcitability associated with a decrease/absence of the extracellular protein LGI1 has been suggested to be primarily due to the downregulation of Kv1 channel expression. The molecular mechanisms underlying this decrease have not yet been elucidated.
Kévin Debreux   +7 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

open access: yesMolecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce   +11 more
wiley   +1 more source

Enrichment-Based Proteogenomics Identifies Microproteins, Missing Proteins, and Novel smORFs in Saccharomyces cerevisiae

open access: yes, 2018
Microproteins are peptides composed of 100 amino acids (AA) or fewer, encoded by small open reading frames (smORFs). It has been demonstrated that microproteins participate in and regulate a wide range of functions in cells.
Chenxi Jia (1311606)   +3 more
core   +1 more source

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