Results 121 to 130 of about 1,344,829 (308)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Molecular Oncology, EarlyView.Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Enrichment-isolation, cortex length and the rank order effect
, 2023 In a previous paper we have proposed a developmental theory to account for the neurological changes which result from differentially rearing animals in either enrichment or isolation.
Robert Cummins (13065627) +1 more
core
Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Forb diversity globally is harmed by nutrient enrichment but can be rescued by large mammalian herbivory [PDF]
Forbs (“wildflowers”) are important contributors to grassland biodiversity but are vulnerable to environmental changes. In a factorial experiment at 94 sites on 6 continents, we test the global generality of several broad predictions: (1) Forb cover and ...
Orr, Devyn +3 more
core
The Principle of Unjust Enrichment [PDF]
The principle of unjust enrichment came into fruition under English law in the last decade. It is now accepted that the four-stage-test "enrichment", "at the expense", "unjust factor" and "no defences" triggers remedies in restitution.
Schall, Alexander
core +1 more source
Meitan kexue jishuExploration breakthroughs of deep coalbed methane (CBM) in the Ordos Basin have driven rapid industry development since 2019. Based on the characteristics of complex coalbed methane (CBM) resource types and strong spatial heterogeneity of reservoir ...
Dehua ZHOU +7 more
doaj +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Meitian dizhi yu kantanObjectiveIn China, the deep coalbed methane (CBM) industry has emerged as a key sector for the reserve growth and production addition of natural gas. However, the current CBM technical standard system, which was developed based on shallow CBM practices ...
Xinjun CHEN +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source