Results 51 to 60 of about 1,893,563 (279)
Principal component gene set enrichment (PCGSE) [PDF]
, 2014 Motivation: Although principal component analysis (PCA) is widely used for the dimensional reduction of biomedical data, interpretation of PCA results remains daunting.
Frost, H. Robert +2 more
core +3 more sources
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Youqi dizhi yu caishouluThe shale oil in the continental faulted basins in eastern China，represented by Jiyang shale oil，has made a breakthrough in production capacity. However，Jiyang shale oil faces great challenges in achieving high and stable production due to the large ...
YANG Yong +9 more
doaj +1 more source
Numerical Simulation on Hydrofracture Propagation in Fractured-Vuggy Unconventional Reservoirs
Geofluids, 2022 The unconventional reservoirs such as carbonate formation develops complex and diverse storage space structures, and it is composed of large-scale cavity, dissolved vug, and fractures. The carbonate reservoir is highly heterogeneous.
Tingxue Jiang +5 more
doaj +1 more source
Molecules, 2021 Over time, stable isotopes have proven to be a useful tool in petroleum geochemistry. However, there is currently insufficient literature on stable isotope geochemistry of the organic elements within shales and crude oils in many petroleum systems around
Abiodun Busuyi Ogbesejana +2 more
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Petroleum Science, 2018 For a typical marine shale reservoir in the Jiaoshiba area, Sichuan Basin of China, P-impedance is sensitive for identifying lithology but not suitable for indicating good shale reservoirs.
Yuan-Yin Zhang +5 more
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Discussion on the uniformity of shale oil and gas in China
Shiyou shiyan dizhiShale oil and gas are important strategic resources in China's energy sector, existing in shale formations with self-generation and self-storage characteristics.
Xusheng GUO +5 more
doaj +1 more source
Microbiome of High-Rank Coal Reservoirs in the High-Production Areas of the Southern Qinshui Basin
Microorganisms, 2023 To study the distribution features of microorganisms in distinct hydrological areas of the southern Qinshui Basin, C-N-S microorganisms were studied using 16S RNA sequencing, metagenome sequencing and geochemical technologies, showing the high ...
Wei Shi, Shuheng Tang, Songhang Zhang
doaj +1 more source