Results 51 to 60 of about 880,441 (304)
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
Due to the limitations of widely used energy spectrum and spectral analyses for the determination of trace elements in coal, the modes of occurrence of Li still remains unclear.
Huidi Hao +3 more
doaj +1 more source
A set of rare earth rich clay rocks is widely distributed in the lower part of The Permian Xuanwei Formation and upper the Emeishan basalt in the Yunnan-Guizhou border region.
Xiaoli Jiang +4 more
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Experimental study on influence of simulated frac hits on shale gas mobility
This study aims to reveal the microscopic migration process of frac hit fluid after invading the matrix and its differential influencing mechanisms on fluid mobility in pores of different scales. Core samples from the main production layer of marine deep
Hua LIU +3 more
doaj +1 more source
Organic-rich source rock was closely related to the development of hydrothermal sedimentation in geochemistry and others. By studying the characteristics of the source rocks of Lower Cambrian Niutitang Formation in Guizhou Province of China, it was found
Zhibin Jia +5 more
doaj +1 more source
BACKGROUNDIn the past two decades, with the development of CBM technology, the reduction of recoverable resources in shallow coalbed methane and the consumption of unconventional natural gas in China increasing year by year, the development of deep ...
Jindong YANG +3 more
doaj +1 more source
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
The Xinhua phosphate mining are alocated in Zhijin County, Guizhou Province, is a famous superlarge low-grade phosphate deposit containing rare earth elements in the southwest of China.The average P2O5 grade of the deposit is 17.22%.The proven ...
Kunping Liang +4 more
doaj +1 more source
Formalizing Enrichment Mechanisms for Bibliographic Ontologies in the Semantic Web [PDF]
This paper presents an analysis of current limitations to the reuse of bibliographic data in the Semantic Web and a research proposal towards solutions to overcome them. The limitations identified derive from the insufficient convergence between existing bibliographic ontologies and the principles and techniques of linked open data (LOD); lack of a ...
Helena Simões Patrício +2 more
openaire +2 more sources

