Results 161 to 170 of about 2,778,759 (291)

Sparse neuronal C4 elevation induces network-wide transcriptomic and lipid-droplet remodeling in the cortical microenvironment. [PDF]

PLoS Comput Biol
Sánchez-Carbonell M, Bolshakova S, Ávila-Pagán JE, Sabir YA, Griffin-Derr C, Stich DG, Cieslewicz SV, Carmen Sifuentes SE, Phadke RA, Brack A, Hasche-Kluender A, Caley P, Dias C, Cruz-Martín A.   +13 more
europepmc   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Joint representation of spliced and unspliced RNA expands information content in single-cell expression data. [PDF]

Bioinform Adv
Jadhav A, DeBruine ZJ.
europepmc   +1 more source

Music enrichment programs improve the neural encoding of speech in at-risk children. [PDF]

J Neurosci, 2014
Kraus N, Slater J, Thompson EC, Hornickel J, Strait DL, Nicol T, White-Schwoch T.   +6 more
europepmc   +1 more source

Baseline Neuroinflammation Stratifies TSPO‐PET Response to Disease‐Modifying Therapy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch, Markus Matilainen, Giulia N. Baldrighi, Marjo Nylund, Maija Saraste, Laura Airas   +5 more
wiley   +1 more source

Inflammaging reshapes the immune ecosystem in IgG4-related dacryoadenitis and sialadenitis. [PDF]

Rheumatology (Oxford)
Yamamoto M, Kamekura R, Uehara M, Ichii Y, Takano K.   +4 more
europepmc   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

A stem-like chromatin program in small-cell lung cancer is associated with poor outcomes after chemoimmunotherapy. [PDF]

Cell Rep Med
Kumar R, Desai P, El Meskini R, Mohindroo C, Benő AÁ, Atkinson D, Nirula M, Bassel L, Takahashi N, Sovacool KL, Meinhardt A, Arora M, Parmar K, Nausome D, Nichols S, Sciuto L, Swift S, Nemes K, Sharma AK, Pate N, Rajan A, Levy E, Kassin M, Aldana CF, Koparde V, Galloux M, Shreshta R, Ohler ZW, Pongor L, Thomas A.   +29 more
europepmc   +1 more source

Diabetes‐Associated Cognitive Impairment: Pathophysiology and Emerging Therapies

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Diabetes‐associated cognitive impairment (DACI) is a common yet underrecognized condition, manifesting along a spectrum from mild cognitive impairment to dementia. DACI encompasses patients who develop vascular dementia (VaD) or Alzheimer's disease (AD) with diabetes as a risk factor; however, in certain patients, particularly those lacking ...
Osman Corbali, Priyanka Menon, Halil I. Corbali, Ram Jagannathan, Allan I. Levey   +4 more
wiley   +1 more source

NET-Associated Transcriptional Signatures and T-Cell Functional States During Allogeneic CAR-γδT-Cell Therapy: A Longitudinal Single-Cell Analysis. [PDF]

Genes (Basel)
Yao L, Liu Z, Wang Y, Gu W, Bai YF.
europepmc   +1 more source