Results 71 to 80 of about 589,246 (317)
Interpreting the effects of DNA polymerase variants at the structural level
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Teachers’ Views: Using Body Music in Teaching and Learning Primary School Subjects
The paper presents research conducted among Turkish primary school classroom teachers regarding their personal and professional views about creating and using KeKeÇa body music games as educational tools.
Muzaffer Özgü Bulut +2 more
doaj +1 more source
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
The exigency of emotion recognition is pushing the envelope for meticulous strategies of discerning actual emotions through the use of superior multimodal techniques.
Mohammad Faridul Haque Siddiqui +1 more
doaj +1 more source
On the variability of projected tropical cyclone genesis in GCM ensembles [PDF]
The development of projections for changes in the genesis of tropical cyclones (TCs) for a changed climate is explored in this article using outputs from the Coupled Model Intercomparison Project: Phase 3 (CMIP3) models. In this study, we explore how the
M. Chattopadhyay, D. Abbs
doaj +1 more source
Abstract Instrumental ensemble playing is a creative process involving real-time interpersonal coordination of sounds, gestures, and musical ideas by two or more musicians. In this chapter, we discuss the psychological mechanisms supporting ensemble coordination.
Bishop, Laura, Keller, Peter E.
openaire +3 more sources
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
Weather forecasts are needed in fire management to support risk-based decision-making that considers both the probability of an outcome and its potential impact.
Den Boychuk +9 more
doaj +1 more source
Improving Estuarine Hydrodynamic Forecasts Through Numerical Model Ensembles
Numerical models are essential tools for the study and analysis of the hydrodynamics of estuarine systems. However, the model results contain uncertainties, which need to be minimized to increase the accuracy of predictions.
Isabel Iglesias +11 more
doaj +1 more source
Mapper is a popular topological data analysis method to analyse structure of complex high‐dimensional data sets. As the Mapper algorithm can be applied to clustering and feature selection with visualization, it is used in various fields such as biology and chemistry.
Sung Jin Kang, Yaeji Lim
openaire +1 more source

