Results 71 to 80 of about 328,404 (292)

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

The Nav1.9 channel regulates colonic motility in mice

Frontiers in Neuroscience, 2013
The colonic migrating motor complex (CMMC) is a major pattern of motility that is entirely generated and organized by the enteric nervous system (ENS). We have previously demonstrated that the Nav1.9 channel underlies a tetrodotoxin-resistant Na+ current
Carine eCopel, Nadine eClerc, Nancy eOsorio, Patrick eDelmas, Bruno eMazet   +4 more
doaj   +1 more source

Development and evaluation of a simple PCR assay and nested PCR for rapid detection of clarithromycin-resistant Helicobacter pylori from culture and directly from the biopsy samples in India

Gut Pathogens, 2023
Background Eradication of Helicobacter pylori provides the most effective treatment for gastroduodenal diseases caused by H. pylori infection. Clarithromycin, a member of the macrolide family, still remains the most important antibiotic used in H. pylori
Bipul Chandra Karmakar, Sangita Paul, Surajit Basak, Manisha Ghosh, Piyali Mukherjee, Rajashree Das, Sujit Chaudhuri, Shanta Dutta, Asish Kumar Mukhopadhyay   +8 more
doaj   +1 more source

Time after time – circadian clocks through the lens of oscillator theory

FEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo, Carolin Ector, Hanspeter Herzel   +2 more
wiley   +1 more source

Fabrication and mechanical testing of polydioxanone hook cross biodegradable self-expandable enteric stent: impact of fabrication density and mechanical properties of the stent [PDF]

Clinical Endoscopy
Background/Aims The mechanical properties of biodegradable stent when fabricated using different number of pins per row of fabrication has been limited. We compared the radial compressive force of polydioxanone (PDO) stent that was fabricated in hook and
Tanyaporn Chantarojanasiri, Juthamas Ratanavaraporn, Saran Keeratihattayakorn   +2 more
doaj   +1 more source

Controlling the bacterial load of Salmonella Typhi in an experimental mouse model by a lytic Salmonella phage STWB21: a phage therapy approach

BMC Microbiology, 2023
Background Salmonella enterica serotype Typhi is one of the major pathogens causing typhoid fever and a public health burden worldwide. Recently, the increasing number of multidrug-resistant strains of Salmonella spp.
Payel Mondal, Prolay Halder, Bani Mallick, Subhadip Bhaumik, Hemanta Koley, Shanta Dutta, Moumita Dutta   +6 more
doaj   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Enteric thymic adenocarcinoma: Understanding a unique pathology in the mediastinum

Indian Journal of Pathology and Microbiology
Thymic malignancies are rare neoplasms, with thymoma and thymic carcinoma—collectively known as thymic epithelial tumors (TETs)—being uncommon tumors that originate from the thymus.
Raja Chhabra, Kartik Mittal, Anmol Tufchi, Sajjan Rajpurohit, Deepak Kumar Mittal, Aditya Vidushi, Swati Saxena, Md Ali Osama   +7 more
doaj   +1 more source

Transplanted human fecal microbiota enhanced Guillain Barré syndrome autoantibody responses after Campylobacter jejuni infection in C57BL/6 mice

Microbiome, 2017
Background Campylobacter jejuni is the leading antecedent infection to the autoimmune neuropathy Guillain-Barré syndrome (GBS), which is accompanied by an autoimmune anti-ganglioside antibody attack on peripheral nerves.
Phillip T. Brooks, Kelsey A. Brakel, Julia A. Bell, Christopher E. Bejcek, Trey Gilpin, Jean M. Brudvig, Linda S. Mansfield   +6 more
doaj   +1 more source

Handbook of Organic Food Safety and Quality [PDF]

, 2007
Handbook of organic food safety and quality - Improve the safety, quality and health benefits of organic foods - Discusses the latest research findings in this area - Focuses on assuring quality and safety throughout the food chain - Quality ...

core   +1 more source