Results 31 to 40 of about 817,024 (288)

Altered epithelial barrier functions in the colon of patients with spina bifida

Scientific Reports, 2022
Our objectives were to better characterize the colorectal function of patients with Spina Bifida (SB). Patients with SB and healthy volunteers (HVs) completed prospectively a standardized questionnaire, clinical evaluation, rectal barostat, colonoscopy ...
Charlène Brochard, Guillaume Bouguen, Raphael Olivier, Tony Durand, Sébastien Henno, Benoît Peyronnet, Mael Pagenault, Chloé Lefèvre, Gaëlle Boudry, Mikael Croyal, Alain Fautrel, Maxime Esvan, Alain Ropert, Anne Dariel, Laurent Siproudhis, Michel Neunlist   +15 more
doaj   +1 more source

Microbiota-gut-brain axis: enteroendocrine cells and the enteric nervous system form an interface between the microbiota and the central nervous system.

Biomedical research, 2020
The microbiota-gut-brain axis transmits bidirectional communication between the gut and the central nervous system and links the emotional and cognitive centers of the brain with peripheral gut functions.
A. Kuwahara, K. Matsuda, Y. Kuwahara, S. Asano, Toshio Inui, Y. Marunaka   +5 more
semanticscholar   +1 more source

Development, Diversity, and Neurogenic Capacity of Enteric Glia

Frontiers in Cell and Developmental Biology, 2022
Enteric glia are a fascinating population of cells. Initially identified in the gut wall as the “support” cells of the enteric nervous system, studies over the past 20 years have unveiled a vast array of functions carried out by enteric glia.
Werend Boesmans, Werend Boesmans, Amelia Nash, Kinga R. Tasnády, Kinga R. Tasnády, Wendy Yang, Wendy Yang, Lincon A. Stamp, Marlene M. Hao   +8 more
doaj   +1 more source

Late-Stage Glioma Is Associated with Deleterious Alteration of Gut Bacterial Metabolites in Mice

Metabolites, 2022
Brain-gut axis refers to the bidirectional functional connection between the brain and the gut, which sustains vital functions for vertebrates. This connection also underlies the gastrointestinal (GI) comorbidities associated with brain disorders.
Aglae Herbreteau, Philippe Aubert, Mikaël Croyal, Philippe Naveilhan, Stéphanie Billon-Crossouard, Michel Neunlist, Yves Delneste, Dominique Couez, Laetitia Aymeric   +8 more
doaj   +1 more source

Histological Evidence for the Enteric Nervous System and the Choroid Plexus as Alternative Routes of Neuroinvasion by SARS-CoV2

Frontiers in Neuroanatomy, 2020
Evidence is mounting that the novel corona virus SARS-CoV2 inflicts neurological symptoms in a subgroup of COVID-19 patients. While plenty of theories on the route of neuroinvasion have been proposed, little histological evidence has been presented ...
Felix Deffner, Melanie Scharr, Stefanie Klingenstein, Moritz Klingenstein, A. Milazzo, S. Scherer, A. Wagner, B. Hirt, A. Mack, Peter H. Neckel   +9 more
semanticscholar   +1 more source

Enteric synucleinopathy: real entity or only a trendy concept?

Free Neuropathology, 2020
An accumulating body of literature has emerged in the past 25 years to show that Parkinson’s disease (PD) is not only a disorder of the brain but also of the gastrointestinal tract and more generally of the gut-brain axis. Gastrointestinal symptoms occur
Adrien de Guilhem de Lataillade, Thibaud Lebouvier, Wendy Noble, Laurene Leclair-Visonneau, Pascal Derkinderen   +4 more
doaj   +1 more source

Neuron–Glia Interaction in the Developing and Adult Enteric Nervous System

Cells, 2020
The enteric nervous system (ENS) constitutes the largest part of the peripheral nervous system. In recent years, ENS development and its neurogenetic capacity in homeostasis and allostasishave gained increasing attention.
Verena Pawolski, Mirko H. H. Schmidt
semanticscholar   +1 more source

Contacting the gut: Mitochondria-associated Endoplasmic Reticulum Membranes in the Enteric Nervous System. [PDF]

Contact (Thousand Oaks)
Changes in the connections between the endoplasmic reticulum (ER) and mitochondria, as well as alterations in mitochondria-associated ER membrane (MAM) signalling, have been documented in various neurodegenerative diseases affecting the brain.
Greig J, Delfino G, Derkinderen P, Paillusson S.   +3 more
europepmc   +2 more sources

You Talking to Me? Says the Enteric Nervous System (ENS) to the Microbe. How Intestinal Microbes Interact with the ENS

Journal of Clinical Medicine, 2020
Mammalian organisms form intimate interfaces with commensal and pathogenic gut microorganisms. Increasing evidence suggests a close interaction between gut microorganisms and the enteric nervous system (ENS), as the first interface to the central nervous
M. Giuffré, R. Moretti, G. Campisciano, Alexandre Barcelos Morais da Silveira, V. M. Monda, M. Comar, Stefano Di Bella, R. M. Antonello, R. Luzzati, L. Crocè   +9 more
semanticscholar   +1 more source

Impact of protein kinase CK2 inhibitors on proliferation and differentiation of neural stem cells

Heliyon, 2017
Background: Protein kinases play central roles in cell and tissue development. Protein kinase CK2, an ubiquitously expressed serine/threonine kinase has severe impacts on embryo- and spermatogenesis.
Melanie Bender, Lisa Schwind, David Grundmann, Monika Martin, Markus Klotz, Claudia Götz, Mathias Montenarh, Karl-Herbert Schäfer   +7 more
doaj   +1 more source