Colistin Resistance in Enterobacterales Strains – A Current View [PDF]
Polish Journal of Microbiology, 2019 Abstract Colistin is a member of cationic polypeptide antibiotics known as polymyxins. It is widely used in animal husbandry, plant cultivation, animal and human medicine and is increasingly used as one of the last available treatment options for patients with severe infections with carbapenem-resistant Gram-negative bacilli.
Elżbieta Stefaniuk, Stefan Tyski
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Updates on the Status of Carbapenem-Resistant Enterobacterales in Lebanon
International Journal of Microbiology, 2023 Carbapenem-resistant Enterobacterales (CRE) pathogens have been increasingly isolated and reported in Lebanon. Several studies have been published over the last two decades about the CRE situation in the country. However, compared to the worldwide data, those studies are scarce and mostly restricted to single center studies.
Mahdi Fadlallah +2 more
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Discordant bioinformatic predictions of antimicrobial resistance from whole-genome sequencing data of bacterial isolates: an inter-laboratory study. [PDF]
, 2019 Antimicrobial resistance (AMR) poses a threat to public health. Clinical microbiology laboratories typically rely on culturing bacteria for antimicrobial-susceptibility testing (AST).
Aller, SD +20 more
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The CARBA-MAP study: national mapping of carbapenemases in Spain (2014–2018) [PDF]
, 2023 Introduction:Infections caused by carbapenem-resistant Enterobacterales (CRE) and carbapenem-resistant Pseudomonas aeruginosa, including isolates producing acquired carbapenemases, constitute a prevalent health problem worldwide. The primary objective of
Arrastia-Erviti, Maitane +41 more
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Disc Diffusion and ComASP® Cefiderocol Microdilution Panel to Overcome the Challenge of Cefiderocol Susceptibility Testing in Clinical Laboratory Routine [PDF]
, 2023 Cefiderocol susceptibility testing represents a major challenge for clinical microbiology. Although disc diffusion showed robustness to test cefiderocol susceptibility, large areas of technical uncertainty (ATU) are reported by current EUCAST breakpoints.
Banche, Giuliana +5 more
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Treatment of infections caused by carbapenemase-producing Enterobacterales
Revista Española de Quimioterapia, 2022 Antibiotic resistance is one of the main menaces to public and individual health worldwide. In the last two decades, an increase in the detection of carbapenem-resistant Enterobacterales has been reported. The treatment of infections caused by these strains is a therapeutic challenge.
Mariana Chumbita +5 more
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Detection of Multidrug-Resistant Enterobacterales—From ESBLs to Carbapenemases [PDF]
Antibiotics, 2021 Multidrug-resistant Enterobacterales (MDRE) are an emerging threat to global health, leading to rising health care costs, morbidity and mortality. Multidrug-resistance is commonly caused by different β-lactamases (e.g., ESBLs and carbapenemases), sometimes in combination with other resistance mechanisms (e.g., porin loss, efflux). The continuous spread
Janina Noster +2 more
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Tracking key virulence loci encoding aerobactin and salmochelin siderophore synthesis in Klebsiella pneumoniae. [PDF]
, 2018 BACKGROUND: Klebsiella pneumoniae is a recognised agent of multidrug-resistant (MDR) healthcare-associated infections; however, individual strains vary in their virulence potential due to the presence of mobile accessory genes.
Brisse, Sylvain +6 more
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Updates on the Virulence Factors Produced by Multidrug-Resistant Enterobacterales and Strategies to Control Their Infections [PDF]
, 2023 The Enterobacterales order is a massive group of Gram-negative bacteria comprised of pathogenic and nonpathogenic members, including beneficial commensal gut microbiota.
Azam M. W., Khan A. U., Zarrilli R.
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In vitro susceptibility of common Enterobacterales to eravacycline in Taiwan
Journal of Microbiology, Immunology and Infection, 2023 New tetracycline derivatives exhibit broad-spectrum antimicrobial activities. This study aimed to assess the in vitro activity of eravacycline against common Enterobacterales.Clinical Enterobacterales isolates were collected between 2017 and 2021. The minimum inhibitory concentration (MIC) was determined using a broth microdilution test.We identified ...
Chun-Fu Huang +4 more
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