Limited effect of patient and disease characteristics on compliance with hospital antimicrobial guidelines [PDF]
Objective: Physicians frequently deviate from guidelines that promote prudent use of antimicrobials. We explored to what extent patient and disease characteristics were associated with compliance with guideline recommendations for three common infections.
A Alvarez+36 more
core +3 more sources
Applications of artificial intelligence‐driven microfluidics in medical laboratory science
The advancements in microfluidics and artificial intelligence are transforming the landscape of Medical Laboratory Science. This article systematically reviews the approaches and applications of AI‐driven microfluidics for analyzing cells, bacteria, nucleic acids, proteins, viruses, and cancer, while also addressing current challenges and proposing ...
Qingyang Jiang+9 more
wiley +1 more source
Capsular profiling of the Cronobacter genus and the association of specific Cronobacter sakazakii and C. malonaticus capsule types with neonatal meningitis and necrotizing enterocolitis [PDF]
Background: Cronobacter sakazakii and C. malonaticus can cause serious diseases especially in infants where they are associated with rare but fatal neonatal infections such as meningitis and necrotising enterocolitis.
A Lehner+57 more
core +2 more sources
To describe the epidemiology of carbapenem-resistant Enterobacteriaceae (CRE) healthcare-associated infections (HAI) in Egyptian hospitals reporting to the national HAI surveillance system.
S. Kotb+12 more
semanticscholar +1 more source
Abstract Background Small intestinal bacterial overgrowth (SIBO) is a clinical and diagnostic challenge in pediatric intestinal failure. This study aimed to assess SIBO and dysbiosis in children with intestinal failure and to analyze clinical characteristics as well as cultural and metagenomic sequencing results from different sampling methods ...
Johannes Hilberath+9 more
wiley +1 more source
Prevalence of Enterobacteriaceae from Clinical Isolates in Federal Teaching Hospital Gombe, Nigeria
Study’s Novelty/Excerpt • This study investigates the prevalence of Enterobacteriaceae in clinical samples from the Federal Teaching Hospital Gombe, providing a comprehensive analysis of 420 non-duplicate isolates over a four-month period.
Saleh, Z. M.+7 more
doaj +1 more source
Massive Increase, Spread, and Exchange of Extended Spectrum {beta}-Lactamase-Encoding Genes Among Intestinal Enterobacteriaceae in Hospitalized Children With Severe Acute Malnutrition in Niger. [PDF]
Background. From the time of CTX-M emergence, extended-spectrum β-lactamase-producing enterobacteria (ESBL-E) have spread worldwide in community settings as well as in hospitals, particularly in developing countries.
Andremont, A+13 more
core +2 more sources
Abstract Objective Irritable bowel syndrome (IBS) is one of the most common functional gastrointestinal disorders, and treatment involves nonpharmacological and pharmacological therapies, even if there is no optimal therapy. This randomized, placebo‐controlled, double‐blind trial aimed to evaluate the efficacy of calcium butyrate supplementation in ...
Fernanda Cristofori+11 more
wiley +1 more source
The continued value of disk diffusion for assessing antimicrobial susceptibility in clinical laboratories: Report from the Clinical and Laboratory Standards Institute Methods Development and Standardization Working Group [PDF]
Expedited pathways to antimicrobial agent approval by the U.S. Food and Drug Administration (FDA) have led to increased delays between drug approval and the availability of FDA-cleared antimicrobial susceptibility testing (AST) devices.
Burnham, Carey-Ann D+6 more
core +2 more sources
Grape Seed Proanthocyanidins: A Potential Microbiome‐Targeted Intervention for Healthy Aging in Rats
Grape seed proanthocyanidin extract (GSPE) promotes a healthier gut phenotype in aged rats. Aging alters gut microbiota composition, increases inflammation, and compromises intestinal barrier function. This study shows that short‐term GSPE treatment in aged rats partially restores microbial diversity toward a youthful profile, modulates mucus‐related ...
Marta Sierra‐Cruz+10 more
wiley +1 more source