Antibiotic resistance pattern of clinical isolates of ESBL strains and determination of enzymatic relationship with clinical specimen type [PDF]
Background: Differences in clinical isolates may affect the frequency of Extended Spectrum Beta-Lactamase enzymes (ESBLs) in some gram-negative bacteria.
Mahyar Porbaran +2 more
doaj +1 more source
Management of carbapenem-resistant Enterobacteriaceae infections [PDF]
Carbapenem resistance is defined as in vitro non-susceptibility to any carbapenem and/or documented production of a carbapenemase. This feature has rapidly spread worldwide among clinical isolates of Enterobacteriaceae, mostly Klebsiella spp., and is associated with diverse molecular mechanisms. Carbapenem resistance is often associated with resistance
Durante-Mangoni, Emanuele +2 more
openaire +4 more sources
Beta-lactamases in Enterobacteriaceae infections in children [PDF]
Multi-drug resistance in Gram negative bacteria, particularly in Enterobacteriaceae, is a major clinical and public health challenge. The main mechanism of resistance in Enterobacteriaceae is linked to the production of beta-lactamase hydrolysing enzymes such as extended spectrum beta-lactamases (ESBL), AmpC beta-lactamases and carbapenemases ...
Stéphane Paulus +3 more
openaire +3 more sources
Extended-Spectrum beta (β)-Lactamases and Antibiogram in Enterobacteriaceae from Clinical and Drinking Water Sources from Bahir Dar City, Ethiopia. [PDF]
The spread of Extended-Spectrum beta (β)-Lactamases (ESBL)-producing Enterobacteriaceae has become a serious global problem. ESBL-producing Enterobacteriaceae vary based on differences in antibiotic use, nature of patients and hospital settings.
Bayeh Abera +2 more
doaj +1 more source
Differential DNA accessibility to polymerase enables 30-minute phenotypic β-lactam antibiotic susceptibility testing of carbapenem-resistant Enterobacteriaceae [PDF]
The rise in carbapenem-resistant Enterobacteriaceae (CRE) infections has created a global health emergency, underlining the critical need to develop faster diagnostics to treat swiftly and correctly.
Garner, Omai B. +5 more
core +1 more source
Treating infections caused by carbapenemase-producing Enterobacteriaceae [PDF]
Carbapenemase-producing Enterobacteriaceae (CPE) have spread worldwide, causing serious infections with increasing frequency. CPE are resistant to almost all available antibiotics, complicating therapy and limiting treatment options. Mortality rates associated with CPE infections are unacceptably high, indicating that the current therapeutic approaches
George L. Daikos +4 more
openaire +3 more sources
Treatment of Infections by OXA-48-Producing Enterobacteriaceae [PDF]
Carbapenemase-producing Enterobacteriaceae (CPE) contribute significantly to the global public health threat of antimicrobial resistance. OXA-48 and its variants are unique carbapenemases with low-level hydrolytic activity toward carbapenems but no intrinsic activity against expanded-spectrum cephalosporins.
Adam Stewart +3 more
openaire +4 more sources
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole +12 more
wiley +1 more source
Enterobacteriaceae populations during experimental Salmonella infection in pigs
Salmonella infection might affect other intestinal Enterobacteriaceae populations and possible correlations between single Enterobacteriaceae populations would help to predict subclinical Salmonella infections in pigs. In one experimental setup, weaned piglets (n=40) were infected with Salmonella and sacrificed at 3h, 24h, 72 h or 28 days post ...
Sebastian Guenther +7 more
openalex +5 more sources
Treatment Options for Carbapenem-Resistant Enterobacteriaceae Infections. [PDF]
Abstract This article provides a comprehensive review of currently available treatment options for infections due to carbapenem-resistant Enterobacteriaceae (CRE). Antimicrobial resistance in Gram-negative bacteria is an emerging and serious global public health threat.
Morrill HJ +3 more
europepmc +6 more sources

