Results 11 to 20 of about 166,249 (334)

Carbapenem-Resistant Enterobacteriaceae Infections in Children. [PDF]

open access: yesCurr Infect Dis Rep, 2016
Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging global public health threat. Infections due to CRE are associated with significant morbidity and mortality. Few therapeutic options are available for treatment of these infections, and optimal antibiotic treatment regimens are unclear.
Chiotos K, Han JH, Tamma PD.
europepmc   +8 more sources

Management of carbapenem-resistant Enterobacteriaceae infections [PDF]

open access: yesClinical Microbiology and Infection, 2019
Carbapenem resistance is defined as in vitro non-susceptibility to any carbapenem and/or documented production of a carbapenemase. This feature has rapidly spread worldwide among clinical isolates of Enterobacteriaceae, mostly Klebsiella spp., and is associated with diverse molecular mechanisms. Carbapenem resistance is often associated with resistance
Durante-Mangoni, Emanuele   +2 more
openaire   +3 more sources

Therapeutic options for carbapenem-resistant Enterobacteriaceae infections. [PDF]

open access: yesVirulence, 2017
In recent years, carbapenem resistance among Enterobacteriaceae has dramatically increased and represents an important threat to global health. The optimal therapeutic management of carbapenem-resistant Enterobacteriaceae (CRE) infections has not been established, because to date, no clinical trials have been performed with this objective.
Trecarichi EM, Tumbarello M.
europepmc   +4 more sources

Treating infections caused by carbapenemase-producing Enterobacteriaceae [PDF]

open access: yesClinical Microbiology and Infection, 2014
Carbapenemase-producing Enterobacteriaceae (CPE) have spread worldwide, causing serious infections with increasing frequency. CPE are resistant to almost all available antibiotics, complicating therapy and limiting treatment options. Mortality rates associated with CPE infections are unacceptably high, indicating that the current therapeutic approaches
Tzouvelekis, L.S.   +4 more
openaire   +3 more sources

Beta-lactamases in Enterobacteriaceae infections in children [PDF]

open access: yesJournal of Infection, 2016
Multi-drug resistance in Gram negative bacteria, particularly in Enterobacteriaceae, is a major clinical and public health challenge. The main mechanism of resistance in Enterobacteriaceae is linked to the production of beta-lactamase hydrolysing enzymes such as extended spectrum beta-lactamases (ESBL), AmpC beta-lactamases and carbapenemases ...
Moxon, Christopher Alan   +1 more
openaire   +2 more sources

A shared mucosal gut microbiota signature in primary sclerosing cholangitis before and after liver transplantation

open access: yesHepatology, EarlyView., 2022
In this study of the gut mucosal microbiota in primary sclerosing cholangitis (PSC), we found consistent microbiota features associated with PSC and recurrent PSC, PSC with inflammatory bowel disease and a persistent gut dysbiosis after liver transplantation Abstract Background and Aims Several characteristic features of the fecal microbiota have been ...
Mikal Jacob Hole   +12 more
wiley   +1 more source

Risk perception of antimicrobial resistance by infection control specialists in Europe: a case-vignette study [PDF]

open access: yes, 2020
Background Using case-vignettes, we assessed the perception of European infection control (IC) specialists regarding the individual and collective risk associated with antimicrobial resistance (AMR) among inpatients.
Ahmad, R.   +5 more
core   +1 more source

Characterization of two polyvalent phages infecting Enterobacteriaceae [PDF]

open access: yesScientific Reports, 2017
AbstractBacteriophages display remarkable genetic diversity and host specificity. In this study, we explore phages infecting bacterial strains of the Enterobacteriaceae family because of their ability to infect related but distinct hosts. We isolated and characterized two novel virulent phages, SH6 and SH7, using a strain of Shigella flexneri as host ...
Sana Hamdi   +6 more
openaire   +2 more sources

Screening forCronobacterSpecies in Powdered and Reconstituted Infant Formulas and from Equipment Used in Formula Preparation in Maternity Hospitals [PDF]

open access: yes, 2013
Background/Aims: Cronobacter spp. have been identified as being of considerable risk to neonates. The occurrence of organism in infant formulas is therefore of considerable interest. Methods: The occurrence of Cronobacter spp.
Amstalden Junqueira, VC   +5 more
core   +1 more source

The Surgical Infection Society revised guidelines on the management of intra-abdominal infection [PDF]

open access: yes, 2017
Background: Previous evidence-based guidelines on the management of intra-abdominal infection (IAI) were published by the Surgical Infection Society (SIS) in 1992, 2002, and 2010. At the time the most recent guideline was released, the plan was to update
Chang, Phillip K   +11 more
core   +3 more sources

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