Results 41 to 50 of about 125,101 (226)

Assessment of extended-spectrum β-lactamases and integrons among Enterobacteriaceae in device-associated infections: multicenter study in north of Iran

Antimicrobial Resistance and Infection Control, 2016
Background Device-associated nosocomial infections (DA-NIs), due to MDR Enterobacteriaceae, are a major threat to patient safety in ICUs. We investigated on Extended-spectrum β-lactamases (ESBL) producing Enterobacteriaceae and incidence of integrons in ...
Masoumeh Bagheri-Nesami, Alireza Rafiei, Gohar Eslami, Fatemeh Ahangarkani, Mohammad Sadegh Rezai, Attieh Nikkhah, Azin Hajalibeig   +6 more
doaj   +1 more source

Targeting Lipopolysaccharide Transport Induces Membrane Lipid Remodeling and Sensitizes Acinetobacter baumannii to Colistin Treatment

Advanced Science, EarlyView.
This study identifies C4 as a lead inhibitor of the Lpt system. Notably, C4 potentiates colistin activity by disrupting LPS transport and remodeling phospholipid homeostasis, revealing a functional interplay between the Lpt and Mla systems. These findings establish a mechanistic link between Lpt inhibition and membrane lipid remodeling, positioning Lpt–
Jianya Luo, Hetianzi Zhang, Jinju Cai, Shuang Zhou, Haijie Zhang, Zhiqiang Wang, Yuan Liu   +6 more
wiley   +1 more source

Detection of OXA-48-Carbapenemase-Producing Enterobacteriaceae using ChromID OXA-48 in Critical Care Patients in Egypt

Journal of Pure and Applied Microbiology, 2017
Carbapenems are a class of beta-lactam antibiotics with broad spectrum of activity. They are often considered as a last resort in treatment of infections caused by multidrug resistant organisms.
Basma A. El Awady, Mera G. Anan, Hamida A. Gohar, Mohamed H. Saleh   +3 more
doaj   +1 more source

Orthopedic Implant-Associated Infection by Multidrug Resistant Enterobacteriaceae [PDF]

Journal of Clinical Medicine, 2019
Introduction: Orthopedic implant-associated infections caused by multidrug-resistant Enterobacteriaceae are a growing challenge for healthcare providers due to their increasing incidence and the difficulties of medical and surgical treatment.
Bernadette G. Pfang, Joaquín García-Cañete, Julia García-Lasheras, Antonio Blanco, Álvaro Auñón, Raul Parron-Cambero, Alicia Macías-Valcayo, Jaime Esteban   +7 more
openaire   +2 more sources

Nano‐Backpack Engineered Probiotics with Reactive Oxygen Species–Responsive Tungsten Release for Synergistic Therapy of Inflammatory Bowel Disease

Advanced Science, EarlyView.
An integrated probiotic system is engineered to execute a programmed therapeutic cascade against inflammatory bowel disease. Upon pathological signals, the system sequentially performs ROS scavenging, tungsten release, and selective pathogen suppression, thereby breaking the oxidative stress–dysbiosis cycle to remodel gut microbiota and reinforce ...
Yang Yang, Liucan Wang, Guoqing Chen, Yuanling Zhang, Jiarui Shi, Wenzhe Fan, Min Yu, Jixi Zhang, Hua Yang   +8 more
wiley   +1 more source

The Gut of Healthy Infants in the Community as a Reservoir of ESBL and Carbapenemase-Producing Bacteria

Antibiotics, 2020
The recent rapid rise of multi-drug resistant Enterobacteriaceae (MDR-E) is threatening the treatment of common infectious diseases. Infections with such strains lead to increased mortality and morbidity.
Ali F. Saleem, Ahreen Allana, Lauren Hale, Alondra Diaz, Raul Salinas, Cristina Salinas, Shahida M. Qureshi, Aneeta Hotwani, Najeeb Rahman, Asia Khan, Anita K. Zaidi, Patrick C. Seed, Mehreen Arshad   +12 more
doaj   +1 more source

qSOFA score: Predictive validity in Enterobacteriaceae bloodstream infections [PDF]

Journal of Critical Care, 2018
To determine whether the quick Sequential Organ Failure Assessment (qSOFA) retains predictive validity in patients with Enterobacteriaceae sepsis that all received appropriate initial antimicrobial therapy.Retrospective cohort at Barnes-Jewish Hospital including individuals with Enterobacteriaceae sepsis receiving appropriate initial antimicrobial ...
Jason P, Burnham, Marin H, Kollef
openaire   +2 more sources

Healthcare-Associated Infections: Enterobacteriaceae Bloodstream Infections in the ICU Settings [PDF]

Infection Control & Hospital Epidemiology, 2020
Background: Bloodstream infections (BSIs) are one of the most frequently observed hospital-acquired infections (HAIs). Objectives: We aimed to describe the epidemiology and drug resistance of hospital-acquired Enterobacteriaceae BSIs and to check for any correlation with the type of hospital care.
Marta KŁOS, Monika Pomorska-Wesołowska, Dorota Romaniszyn, Agnieszka Chmielarczyk, Jadwiga Wojkowska-Mach   +4 more
openaire   +1 more source

Microalgae Hybrid Biosystem for Enhanced Oral Delivery of Rifaximin in Hepatic Encephalopathy Treatment

Advanced Science, EarlyView.
The microalgae‐nanoparticle hybrid system with antibacterial activity can improve the oral delivery and therapeutic efficiency for hepatic encephalopathy treatment. Oral administration of the system can reduced systemic ammonia levels, enhanced intestinal barrier function, attenuated systemic and neuroinflammation, ameliorated cognitive impairments ...
Kaiyue Wang, Xueting Huang, Lingxiao Yang, Jin Liu, Lei Lei, Shaomin Zou, Kai Wang, Min Zhou, Zhe Tang   +8 more
wiley   +1 more source

Expression of Recombinant OmpA (rOmpA) and In vitro Validation of Antibody Mediated Cross Reactivity among the Enterobacteriaceae Pathogens

Journal of Pure and Applied Microbiology
Enterobacteriaceae pathogens such as Escherichia coli, Salmonella sp., Shigella sp., Proteus sp., and Klebsiella pneumoniae cause a wide range of gastrointestinal and other mucosal infections. These bacteria acquire antibiotic resistance very quickly and
Harish Babu Kolla, S. Sai Latha, Prakash Narayana Reddy, Shivakiran Satyanarayan Makam, Devika Veluvolu   +4 more
doaj   +1 more source