Results 61 to 70 of about 168,470 (330)

Clinical and Mortality Risk Factors in Bloodstream Infections with Carbapenem-Resistant Enterobacteriaceae

Canadian Journal of Infectious Diseases and Medical Microbiology, 2017
Objective. To investigate the risk factors underlying the occurrence and mortality of bloodstream infections (BSIs) with carbapenem-resistant Enterobacteriaceae (CRE). Methods.
Xiaopeng Li, Huan Ye
doaj   +1 more source

The Gut of Healthy Infants in the Community as a Reservoir of ESBL and Carbapenemase-Producing Bacteria

Antibiotics, 2020
The recent rapid rise of multi-drug resistant Enterobacteriaceae (MDR-E) is threatening the treatment of common infectious diseases. Infections with such strains lead to increased mortality and morbidity.
Ali F. Saleem, Ahreen Allana, Lauren Hale, Alondra Diaz, Raul Salinas, Cristina Salinas, Shahida M. Qureshi, Aneeta Hotwani, Najeeb Rahman, Asia Khan, Anita K. Zaidi, Patrick C. Seed, Mehreen Arshad   +12 more
doaj   +1 more source

Microbiological screening is necessary to distinguish carriers of plasmid-mediated AmpC beta-lactamase-producing enterobacteriaceae and extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae because of clinical similarity. [PDF]

PLoS ONE, 2015
Plasmid-mediated AmpC beta-lactamase-producing (pAmpC) Enterobacteriaceae are increasing worldwide, difficult to identify and often confounded with extended-spectrum beta-lactamase (ESBL) producers.
Anna Conen, Reno Frei, Hildegard Adler, Marc Dangel, Christoph A Fux, Andreas F Widmer   +5 more
doaj   +1 more source

The spread of multi drug resistant infections is leading to an increase in the empirical antibiotic treatment failure in cirrhosis: a prospective survey [PDF]

, 2015
Background The spread of multi-resistant infections represents a continuously growing problem in cirrhosis,particularly in patients in contact with the healthcare environment.
Ceccarelli, Giancarlo, Di Gregorio, Vincenza, Falcone, Marco, Farcomeni, Alessio, Giannelli, Valerio, Giusto, Michela, Lattanzi, Barbara, Lucidi, Cristina, Merli, Manuela, Riggio, Oliviero, Venditti, Mario   +10 more
core   +2 more sources

A Bifunctional T3SS‐Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Advanced Science, EarlyView.
Pathogenic bacteria exploit the metalloprotease effector NleD to subvert host defenses. Structural, biochemical, and infection analyses reveal a bifunctional mechanism by which NleD binds and inhibits the host phosphatase PPM1A while preserving its proteolytic activity against MAPKs.
Yaakov Socol, Lihi Gur‐Arie, Netanel Tzarum, Tamara Wellins, Naama Katsowich, Miriam Ravins, Michal Bejerano‐Sagie, Klil Cohen, Oded Livnah, Joshua N. Adkins, Ernesto Nakayasu, Alexei Savchenko, Yeu Khai Choong, Nikhil Kumar Tulsian, Saturo Machida, Sigal Ben‐Yehuda, Yael Litvak, J. Sivaraman, Ilan Rosenshine   +18 more
wiley   +1 more source

Midgut microbiota of the malaria mosquito vector Anopheles gambiae and Interactions with plasmodium falciparum Infection [PDF]

, 2012
The susceptibility of Anopheles mosquitoes to Plasmodium infections relies on complex interactions between the insect vector and the malaria parasite.
A Chao, A Rani, AK Benson, Alexandra Marie, AM Briones, AM Mendes, Anne Boissière, AV Santos, B Chouaia, C Costantini, C Dale, C Damiani, C Fanello, C Gouveia, C Harris, C Wondji, CA Lowenberger, CB Pumpuni, CB Pumpuni, CD Marsden, CJF Ter Braak, CJF Ter Braak, CM Cirimotich, Dipankar Bachar, E Crotti, E Crotti, E Zaura, Elena A. Levashina, F Armougom, F Simard, FH Collins, G Avgustin, G Elango, G Favia, G Reid, Hamid R. Shahbazkia, II Ivanov, Isabelle Morlais, J Jadin, J Okasen, J Qin, J Rodrigues, JF Petrosino, JM Lindh, K Zouache, KD Vernick, Kenneth D. Vernick, KM Maslowski, KS Hayes, KW Mah, L Gonzalez-Ceron, Luc Abate, LV Hooper, LV Hooper, M Farenhorst, M Kane, Majoline T. Tchioffo, ME Bruno, MK Lawniczak, ML Metzker, ML Sogin, MM Riehle, MO Ndiath, MS Beier, N Buchon, N Windbichler, O Terenius, P Kampfer, Parfait H. Awono-Ambene, PJ Turnbaugh, R Andreotti, R Christen, R Fabre, R Kindt, R Miyata, RE Ley, RE Ley, Richard Christen, RJ Dillon, RJ Dillon, RM Moll, S Compant, S Meister, SA Blandin, Sandrine E. Nsango, SC Straif, SK Kuss, SM Geib, T Stoeck, TL Turner, U Hentschel, VG Martinson, Y Dong, Y Kikuchi, Y Kikuchi   +94 more
core   +6 more sources

Discovery of H2 Receptor Antagonists as Colistin Enhancers by Targeting Acid Stress Response

Advanced Science, EarlyView.
This study identifies YqgB as a key target for restoring colistin susceptibility in mcr‐positive pathogens under acidic conditions by remodeling phospholipid composition and reducing LPS modification. Deep learning‐based screening reveals H2 receptor antagonists as novel colistin adjuvants. Further investigations indicate that ranitidine and famotidine
Jinju Cai, Mengping He, Jianya Luo, Shuang Zhou, Tengyue Zhang, Jianing Li, Zhiqiang Wang, Yuan Liu   +7 more
wiley   +1 more source

Assessment of extended-spectrum β-lactamases and integrons among Enterobacteriaceae in device-associated infections: multicenter study in north of Iran

Antimicrobial Resistance and Infection Control, 2016
Background Device-associated nosocomial infections (DA-NIs), due to MDR Enterobacteriaceae, are a major threat to patient safety in ICUs. We investigated on Extended-spectrum β-lactamases (ESBL) producing Enterobacteriaceae and incidence of integrons in ...
Masoumeh Bagheri-Nesami, Alireza Rafiei, Gohar Eslami, Fatemeh Ahangarkani, Mohammad Sadegh Rezai, Attieh Nikkhah, Azin Hajalibeig   +6 more
doaj   +1 more source

Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) isolated from bean sprouts in the Netherlands. [PDF]

PLoS ONE, 2018
Community-acquired carriage and infections due to extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) are increasing worldwide, resulting in increased morbidity, mortality and healthcare costs.
Pepijn Huizinga, Eefje Schrauwen, Silvia García-Cobos, Ina Willemsen, Carlo Verhulst, Alexander W Friedrich, Paul H M Savelkoul, John W Rossen, Jan Kluytmans   +8 more
doaj   +1 more source

Prevalence of Carbapenemase and Extended-Spectrum β-Lactamase Producing Enterobacteriaceae: A Cross-Sectional Study

Antibiotics, 2023
Enterobacteriaceae have been classified as severely drug resistant bacteria by the World Health Organization due to their extensive production and dissemination of carbapenemases (CPs) and extended-spectrum β-lactamases (ESBL).
Muhammad Muqaddas Mustafai, Mavra Hafeez, Safa Munawar, Sakeenabi Basha, Ali A. Rabaan, Muhammad A. Halwani, Abdulsalam Alawfi, Amer Alshengeti, Mustafa A. Najim, Sara Alwarthan, Meshal K. AlFonaisan, Souad A. Almuthree, Mohammed Garout, Naveed Ahmed   +13 more
doaj   +1 more source