Present and Future of Carbapenem-resistant Enterobacteriaceae (CRE) Infections [PDF]
Carbapenem-resistant Enterobacteriaceae (CRE) have become a public health threat worldwide. There are three major mechanisms by which Enterobacteriaceae become resistant to carbapenems: enzyme production, efflux pumps and porin mutations. Of these, enzyme production is the main resistance mechanism.
Beatriz Suay-García +1 more
openaire +4 more sources
Case series of carbapenemase-producing Enterobacteriaceae osteomyelitis: Feel it in your bones
Objectives: Limited data have been reported regarding osteomyelitis due to carbapenemase-producing Enterobacteriaceae (CPE), including co-infections with extended-spectrum β-lactamase (ESBL)-producing micro-organisms.
B. Davido +12 more
doaj +1 more source
Enterobacteriaceae Bloodstream Infections: Presence of Integrons, Risk Factors, and Outcome [PDF]
ABSTRACT A prospective observational study was conducted to identify factors associated with bloodstream infections (BSIs) caused by integron-carrying Enterobacteriaceae and to evaluate the clinical significance of integron carriage. Consecutive patients with Enterobacteriaceae BSIs
Daikos, George L. +8 more
openaire +4 more sources
Endogenous Enterobacteriaceae underlie variation in susceptibility to Salmonella infection [PDF]
Lack of reproducibility is a prominent problem in biomedical research. An important source of variation in animal experiments is the microbiome, but little is known about specific changes in the microbiota composition that cause phenotypic differences.
Eric M. Velazquez +16 more
openaire +4 more sources
Background: Carbapenem-resistant Enterobacteriaceae (CRE) are an important cause of infections in cancer patients. The proportion of carbapenem resistance and the types of carbapenemase-encoding genes in Enterobacteriaceae isolated from cancer patients ...
Gayashan Chathuranga +3 more
doaj +1 more source
Objective. To investigate the risk factors underlying the occurrence and mortality of bloodstream infections (BSIs) with carbapenem-resistant Enterobacteriaceae (CRE). Methods.
Xiaopeng Li, Huan Ye
doaj +1 more source
The recent rapid rise of multi-drug resistant Enterobacteriaceae (MDR-E) is threatening the treatment of common infectious diseases. Infections with such strains lead to increased mortality and morbidity.
Ali F. Saleem +12 more
doaj +1 more source
Microbiological screening is necessary to distinguish carriers of plasmid-mediated AmpC beta-lactamase-producing enterobacteriaceae and extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae because of clinical similarity. [PDF]
Plasmid-mediated AmpC beta-lactamase-producing (pAmpC) Enterobacteriaceae are increasing worldwide, difficult to identify and often confounded with extended-spectrum beta-lactamase (ESBL) producers.
Anna Conen +5 more
doaj +1 more source
An analysis of risk factors for carbapenem-resistant Enterobacteriaceae infection
This study aims to explore the high-risk factors of carbapenem-resistant Enterobacteriaceae (CRE) infection of hospitalised patients in high-risk departments.This study is a multicentre, retrospective study. CRE screening positive patients from 1 January 2016 to 31 December 2018 of high-risk departments in five tertiary first-class teaching hospitals ...
Yan Gao +14 more
openaire +3 more sources
Clinical outcomes of Enterobacteriaceae infections stratified by carbapenem MICs. [PDF]
ABSTRACT The Clinical and Laboratory Standards Institute (CLSI) lowered the MIC breakpoints for meropenem and imipenem from 4 mg/liter to 1 mg/liter for Enterobacteriaceae in 2010. The breakpoint change improves the probability of pharmacodynamic target attainment and eliminates the need for microbiology ...
Patel TS, Nagel JL.
europepmc +4 more sources

