Beta-lactamases in Enterobacteriaceae infections in children [PDF]
Journal of Infection, 2016 Multi-drug resistance in Gram negative bacteria, particularly in Enterobacteriaceae, is a major clinical and public health challenge. The main mechanism of resistance in Enterobacteriaceae is linked to the production of beta-lactamase hydrolysing enzymes such as extended spectrum beta-lactamases (ESBL), AmpC beta-lactamases and carbapenemases ...
Moxon, Christopher Alan +1 more
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Treating infections caused by carbapenemase-producing Enterobacteriaceae [PDF]
Clinical Microbiology and Infection, 2014 Carbapenemase-producing Enterobacteriaceae (CPE) have spread worldwide, causing serious infections with increasing frequency. CPE are resistant to almost all available antibiotics, complicating therapy and limiting treatment options. Mortality rates associated with CPE infections are unacceptably high, indicating that the current therapeutic approaches
Tzouvelekis, L.S. +4 more
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Perioperative prophylaxis with ertapenem reduced infections caused by extended-spectrum betalactamase-producting Enterobacteriaceae after kidney transplantation [PDF]
BMC Nephrology, 2019 Backgound In recent years we have witnessed an increase in infections due to multidrug-resistant organisms in kidney transplant recipients (KTR). In our setting, we have observed a dramatic increase in infections caused by extended-spectrum betalactamase-
Gemma Sanclemente +9 more
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GMS Infectious Diseases, 2020 This is the sixteenth chapter of the guideline “Calculated initial parenteral treatment of bacterial infections in adults – update 2018” in the 2 updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been
Grabein, Béatrice +3 more
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Clinical and Mortality Risk Factors in Bloodstream Infections with Carbapenem-Resistant Enterobacteriaceae [PDF]
Canadian Journal of Infectious Diseases and Medical Microbiology, 2017 Objective. To investigate the risk factors underlying the occurrence and mortality of bloodstream infections (BSIs) with carbapenem-resistant Enterobacteriaceae (CRE). Methods.
Xiaopeng Li, Huan Ye
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Carbapenem Resistant Enterobacteriaceae infections in Houston, Texas: An outline [PDF]
Online J Public Health Inform, 2017 ObjectiveTo examine demographic as well as clinical characteristics of theCarbapenam Resistant Enteriobacteriacae (CRE) Organisms cases inHouston, Texas, 2015-2016IntroductionAccording to CDC, CRE is used to describe bacteria that are non-susceptible to one or more carbapenems; doripenem, meropenemor imipenem and resistant to third generation ...
Rehman, Hafeez +3 more
europepmc +3 more sources
Clinical outcomes of Enterobacteriaceae infections stratified by carbapenem MICs. [PDF]
J Clin Microbiol, 2015 ABSTRACT The Clinical and Laboratory Standards Institute (CLSI) lowered the MIC breakpoints for meropenem and imipenem from 4 mg/liter to 1 mg/liter for Enterobacteriaceae in 2010. The breakpoint change improves the probability of pharmacodynamic target attainment and eliminates the need for microbiology ...
Patel TS, Nagel JL.
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Risk factors and treatment advances for carbapenem-resistant Enterobacteriaceae infections in the urinary tract [PDF]
Frontiers in Cellular and Infection MicrobiologyZhang X, Miao S, Ji C, Hu W.
exaly +2 more sources
The Clinical and Molecular Epidemiology of CTX-M-9 Group Producing Enterobacteriaceae Infections in Children [PDF]
Infectious Diseases and Therapy, 2019 Robert Bonomo +2 more
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Management of carbapenem-resistant Enterobacteriaceae infections [PDF]
Clinical Microbiology and Infection, 2019 Carbapenem resistance is defined as in vitro non-susceptibility to any carbapenem and/or documented production of a carbapenemase. This feature has rapidly spread worldwide among clinical isolates of Enterobacteriaceae, mostly Klebsiella spp., and is associated with diverse molecular mechanisms. Carbapenem resistance is often associated with resistance
Durante-Mangoni, Emanuele +2 more
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