Results 11 to 20 of about 124,514 (155)
Treatment of Carbapenem-Resistant Enterobacteriaceae Infections in Children. [PDF]
J Pediatric Infect Dis Soc, 2020 AbstractInfections due to carbapenem-resistant Enterobacteriaceae (CRE) are increasingly prevalent in children and are associated with poor clinical outcomes. Optimal treatment strategies for CRE infections continue to evolve. A lack of pediatric-specific comparative effectiveness data, uncertain pediatric dosing regimens for several agents, and a ...
Chiotos K, Hayes M, Gerber JS, Tamma PD.
europepmc +4 more sources
Carbapenem-Resistant Enterobacteriaceae Infections in Children. [PDF]
Curr Infect Dis Rep, 2016 Carbapenem-resistant Enterobacteriaceae (CRE) are an emerging global public health threat. Infections due to CRE are associated with significant morbidity and mortality. Few therapeutic options are available for treatment of these infections, and optimal antibiotic treatment regimens are unclear.
Chiotos K, Han JH, Tamma PD.
europepmc +8 more sources
Management of carbapenem-resistant Enterobacteriaceae infections [PDF]
Clinical Microbiology and Infection, 2019 Carbapenem resistance is defined as in vitro non-susceptibility to any carbapenem and/or documented production of a carbapenemase. This feature has rapidly spread worldwide among clinical isolates of Enterobacteriaceae, mostly Klebsiella spp., and is associated with diverse molecular mechanisms. Carbapenem resistance is often associated with resistance
Durante-Mangoni, Emanuele +2 more
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Beta-lactamases in Enterobacteriaceae infections in children [PDF]
Journal of Infection, 2016 Multi-drug resistance in Gram negative bacteria, particularly in Enterobacteriaceae, is a major clinical and public health challenge. The main mechanism of resistance in Enterobacteriaceae is linked to the production of beta-lactamase hydrolysing enzymes such as extended spectrum beta-lactamases (ESBL), AmpC beta-lactamases and carbapenemases ...
Moxon, Christopher Alan +1 more
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Treatment of Infections by OXA-48-Producing Enterobacteriaceae [PDF]
Antimicrobial Agents and Chemotherapy, 2018 Carbapenemase-producing Enterobacteriaceae (CPE) contribute significantly to the global public health threat of antimicrobial resistance. OXA-48 and its variants are unique carbapenemases with low-level hydrolytic activity toward carbapenems but no intrinsic activity against expanded-spectrum cephalosporins.
Adam Stewart +3 more
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INCIDENCE OF ENTEROBACTERIACEAE IN NOSOCOMIAL INFECTIONS
ANNALS OF THE UNIVERSITY OF CRAIOVA, Biology, Horticulture, Food products processing technology, Environmental engineering, 2023 This work was carried out in the field of General Microbiology, combining in its contents elements of different biological, medical and technological disciplines.The special part of this paper included a study at the Tg-Jiu County Emergency Hospital, where we made a statistic during a calendar year on the number of hospitalized patients, detected with ...
Eleonora Daniela Ciupeanu Călugăru +1 more
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Treating infections caused by carbapenemase-producing Enterobacteriaceae [PDF]
Clinical Microbiology and Infection, 2014 Carbapenemase-producing Enterobacteriaceae (CPE) have spread worldwide, causing serious infections with increasing frequency. CPE are resistant to almost all available antibiotics, complicating therapy and limiting treatment options. Mortality rates associated with CPE infections are unacceptably high, indicating that the current therapeutic approaches
Tzouvelekis, L.S. +4 more
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Characterization of two polyvalent phages infecting Enterobacteriaceae [PDF]
Scientific Reports, 2017 AbstractBacteriophages display remarkable genetic diversity and host specificity. In this study, we explore phages infecting bacterial strains of the Enterobacteriaceae family because of their ability to infect related but distinct hosts. We isolated and characterized two novel virulent phages, SH6 and SH7, using a strain of Shigella flexneri as host ...
Sana Hamdi +6 more
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PLoS ONE, 2016 BackgroundThe spread of Extended-Spectrum beta (β)-Lactamases (ESBL)-producing Enterobacteriaceae has become a serious global problem. ESBL-producing Enterobacteriaceae vary based on differences in antibiotic use, nature of patients and hospital settings.
Bayeh Abera +2 more
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GMS Infectious Diseases, 2020 This is the sixteenth chapter of the guideline “Calculated initial parenteral treatment of bacterial infections in adults – update 2018” in the 2 updated version. The German guideline by the Paul-Ehrlich-Gesellschaft für Chemotherapie e.V. (PEG) has been
Grabein, Béatrice +3 more
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