Results 61 to 70 of about 166,249 (334)

Measures to eradicate multidrug-resistant organism outbreaks: How much does it cost? [PDF]

, 2015
This study aimed to assess the economic burden of infection control measures that succeeded in eradicating multidrug-resistant organisms (MDROs) in emerging epidemic contexts in hospital settings.
Birgand, GJC, Bourigault, C, Holmes, A, Iucet, JC, Lepelletier, D, Moore, L, Vella, V   +6 more
core   +1 more source

Clinical and Mortality Risk Factors in Bloodstream Infections with Carbapenem-Resistant Enterobacteriaceae

Canadian Journal of Infectious Diseases and Medical Microbiology, 2017
Objective. To investigate the risk factors underlying the occurrence and mortality of bloodstream infections (BSIs) with carbapenem-resistant Enterobacteriaceae (CRE). Methods.
Xiaopeng Li, Huan Ye
doaj   +1 more source

Prevalence of Carbapenemase and Extended-Spectrum β-Lactamase Producing Enterobacteriaceae: A Cross-Sectional Study

Antibiotics, 2023
Enterobacteriaceae have been classified as severely drug resistant bacteria by the World Health Organization due to their extensive production and dissemination of carbapenemases (CPs) and extended-spectrum β-lactamases (ESBL).
Muhammad Muqaddas Mustafai, Mavra Hafeez, Safa Munawar, Sakeenabi Basha, Ali A. Rabaan, Muhammad A. Halwani, Abdulsalam Alawfi, Amer Alshengeti, Mustafa A. Najim, Sara Alwarthan, Meshal K. AlFonaisan, Souad A. Almuthree, Mohammed Garout, Naveed Ahmed   +13 more
doaj   +1 more source

Multilocus sequence typing of Cronobacter spp. from powdered infant formula and milk powder production factories [PDF]

, 2013
This study applied the Cronobacter spp. multilocus sequence typing (MLST) scheme to three strain collections, then known as Enterobacter sakazakii, which had been isolated between 1988 and 2009 from 14 countries. The results revealed the predominance (85%
Craven, HM, Forsythe, SJ, Joseph, F, McAuley, CM, Sonbol, H   +4 more
core   +1 more source

Healthcare-Associated Infections: Enterobacteriaceae Bloodstream Infections in the ICU Settings [PDF]

Infection Control & Hospital Epidemiology, 2020
Background: Bloodstream infections (BSIs) are one of the most frequently observed hospital-acquired infections (HAIs). Objectives: We aimed to describe the epidemiology and drug resistance of hospital-acquired Enterobacteriaceae BSIs and to check for any correlation with the type of hospital care.
Marta KŁOS, Monika Pomorska-Wesołowska, Dorota Romaniszyn, Agnieszka Chmielarczyk, Jadwiga Wojkowska-Mach   +4 more
openaire   +1 more source

Dipiperazine‐Phenyl Derivatives Based on Convergent Molecular Platforms Can Reverse Multidrug Resistance in Gram‐Negative Bacteria by Inhibiting Efflux and Permeabilizing Cell Membranes

Advanced Science, EarlyView.
By integrating a convergent molecular platform strategy, this study designed a novel dual‐target C5 to combat multidrug‐resistant Gram‐negative bacteria. C5 synergistically enhances antibiotic efficacy by inhibiting efflux pumps and increasing bacterial membrane permeability.
Jiale Dong, Ting Guo, Yi Huang, Yangchun Ma, Weijin Chen, Jie Xue, Jun Jiang, Enhui Dong, Yue Kong, Hang Ding, Wenlong Zhang, Shutao Ma   +11 more
wiley   +1 more source

Extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) isolated from bean sprouts in the Netherlands. [PDF]

PLoS ONE, 2018
Community-acquired carriage and infections due to extended-spectrum beta-lactamase producing Enterobacteriaceae (ESBL-E) are increasing worldwide, resulting in increased morbidity, mortality and healthcare costs.
Pepijn Huizinga, Eefje Schrauwen, Silvia García-Cobos, Ina Willemsen, Carlo Verhulst, Alexander W Friedrich, Paul H M Savelkoul, John W Rossen, Jan Kluytmans   +8 more
doaj   +1 more source

Escherichia coli of sequence type 3835 carrying blaNDM-1, blaCTX-M-15, blaCMY-42 and blaSHV-12 [PDF]

, 2015
New Delhi metallo-β-lactamase (NDM) represents a serious challenge for treatment and public health. A carbapenem-resistant Escherichia coli clinical strain WCHEC13-8 was subjected to antimicrobial susceptibility tests, whole genome sequencing and ...
Feng, Y, McNally, A, Wang, X, Xie, Y, Yang, P, Zong, Z   +5 more
core   +1 more source

Development of an in situ small intestinal injection technique for targeted macromolecule delivery and in vivo functional studies in mice

Animal Models and Experimental Medicine, EarlyView.
This study developed a minimally invasive, in situ small intestinal injection technique for mice, enabling targeted delivery of bioactive molecules while bypassing gastric degradation. Validation using functional assays and single‐cell RNA sequencing reveals high‐mobility group box 1–mediated epithelial responses, offering a translational tool for gut ...
Yawen Lai, Xintao Zhang, Tingting Luo, Wenhan Chen, Chenyu Ma, Haihua Luo, Jinghua Liu, Jia Xu   +7 more
wiley   +1 more source

Assessment of extended-spectrum β-lactamases and integrons among Enterobacteriaceae in device-associated infections: multicenter study in north of Iran

Antimicrobial Resistance and Infection Control, 2016
Background Device-associated nosocomial infections (DA-NIs), due to MDR Enterobacteriaceae, are a major threat to patient safety in ICUs. We investigated on Extended-spectrum β-lactamases (ESBL) producing Enterobacteriaceae and incidence of integrons in ...
Masoumeh Bagheri-Nesami, Alireza Rafiei, Gohar Eslami, Fatemeh Ahangarkani, Mohammad Sadegh Rezai, Attieh Nikkhah, Azin Hajalibeig   +6 more
doaj   +1 more source