JAK Inhibitor Upadacitinib Induces Remission in Refractory Immune-Related Colitis Triggered by CTLA-4 and PD-1 Inhibitor Combination Therapy in Malignant Pleural Mesothelioma: A Case Report. [PDF]
Cancer Rep (Hoboken)ABSTRACT Background Immune checkpoint inhibitors have demonstrated efficacy against various cancers; however, there is a rising incidence of immune‐related colitis. Some cases of immune‐related colitis prove resistant to treatment, even with the administration of glucocorticoids or infliximab, and there is currently no established standard treatment ...
Kono M +10 more
europepmc +2 more sources
Role of TLR4 in Enteric Glia Response to Clostridioides Difficile Toxins: Insights From In Vivo and In Vitro Studies. [PDF]
J Cell Mol MedABSTRACT Clostridioides difficile (C. difficile ) is a Gram‐positive anaerobic bacillus that causes intestinal disorders. Toll‐like receptor 4 (TLR4) plays a key role in innate immunity. This study examines the role of TLR4 in the response to C. difficile toxins, which induce cell death and inflammatory responses in enteric glial cells (EGCs).
Barbosa MLL +6 more
europepmc +2 more sources
Ischemic Colitis Presented as Pseudomembranous Colitis: An Untypical Case from Vietnam
The Korean Journal of Gastroenterology, 2022 Ischemic colitis (IC) is an underreported chronic disease characterized by the hypoperfusion of the bowel mucosa. The diagnosis and treatment may be challenging because its clinical course resembles other colitis or even colorectal malignancies.
Tien Manh Huynh +5 more
doaj +1 more source
Antibiotics, 2022 The majority of recently published studies indicate a greater incidence rate and mortality due to Clostridioides difficile infection (CDI) in patients with chronic kidney disease (CKD).
Łukasz Lis +6 more
doaj +1 more source
Pseudomembranous colitis in children: Experience of a university hospital in Korea [PDF]
, 2010 Purpose : Pseudomembranous colitis (PMC) occurs rarely in children, but its incidences are increasing due to frequent antibiotic use. We investigated the incidence and clinical characteristics of PMC accompanied by bacterial enteritis-like symptoms in ...
Ae Suk Kim +27 more
core +1 more source
Refractory Infection Cured With Fecal Microbiota Transplantation in Vancomycin-Resistant Enterococcus Colonized Patient [PDF]
Intestinal Research, 2015 The rates and severity of Clostridium difficile infections, including pseudomembranous colitis, have increased markedly. However, there are few effective treatments for refractory or recurrent C. difficile infections and the outcomes are poor.
Mi-Ok Jang +3 more
doaj +1 more source
Imaging of ischemia, obstruction and infection in the abdomen [PDF]
, 2018 Intestinal ischemia is a serious condition that continues to be associated with mortalities in excess of 70%. Intestinal obstruction and gastrointestinal tract sepsis are common conditions, accounting for a large proportion of patients admitted to ...
Maher, Michael M. +4 more
core +1 more source
Laboratorium Diagnosis of Clostridium Difficile Infection [PDF]
, 2006 Clostridium difficile is the most important cause of antibiotic associated diarrhea, and pseudomembranous colitis, a severe infection of the colon.
Legoh, G. N. (Grace) +1 more
core +1 more source
Acute necrotizing (pseudomembranous) enterocolitis
Journal of British Surgery, 1958 A W, KAY, R L, RICHARDS, A J, WATSON
openaire +3 more sources
Fulminant pseudomembranous enterocolitis caused by Klebsiella oxytoca: an autopsy case report
Acute Medicine & Surgery, 2018 We describe a rare case of antibiotic‐associated fulminant pseudomembranous enterocolitis caused by Klebsiella oxytoca. A 79‐year‐old man with a history of antibiotic therapy was admitted to our emergency department, complaining of consciousness ...
Tatsunori Nagamura +14 more
semanticscholar +1 more source