Results 31 to 40 of about 2,460 (186)

The Simple Predictors of Pseudomembranous Colitis in Patients with Hospital-Acquired Diarrhea: A Prospective Observational Study

Gut and Liver, 2014
Background/AimsAs the incidence rate of and mortality from pseudomembranous colitis (PMC) are increasing worldwide, it is important to study the simple predictive risk factors for PMC among patients with hospital-acquired diarrhea (HAD).
doaj   +1 more source

Microbiota–Host Interactions: Exploring Their Dynamics and Contributions to Human Diseases

MicrobiologyOpen, Volume 14, Issue 4, August 2025.
Bacterial dysbiosis results from microbiota imbalances, diet, lifestyle, and other factors that lead to conditions such as IBS, IBD, acne, dermatitis, and dental diseases. The current therapeutic approaches include probiotics, prebiotics, synbiotics, microbiota transplantation, and phage therapy.
Siau Wui Chin, Zheng Yao Low, Wei Qi Tan, Adzzie Shazleen Azman   +3 more
wiley   +1 more source

Machine Learning Reveals the Value of Unconventional T Lymphocytes in Sepsis and Prognosis of Elderly Patients With Severe Lower Respiratory Tract Infections

Journal of Clinical Laboratory Analysis, Volume 39, Issue 14, July 2025.
Initially, 166 subjects aged 65 years or older with severe LRTIs met the diagnostic criteria, but 30 cases were excluded due to incomplete clinical data, and 17 cases were excluded due to the presence of malignancies, connective tissue diseases, or long‐term use of immunosuppressive agents. Ultimately, 119 patients were included in the study. The study
Tianqi Qi, Qian Gao, Yan Song, Yulin Li, Yanlan Yao, Xinyue Liu, Manyu Li, Jingxian Yang, Qi Hao   +8 more
wiley   +1 more source

Identification of locally isolated clostridium difficile from rabbits [PDF]

, 2019
Clostridium difficile is one of the most important pathogens causing diarrhea and enteritis in rabbits as it causes pseudomembranous colitis that leads to intestinal damage and deaths. In this study, screening of rabbit farms from different localities in
Abdella, Y. A., El Sawy, H., El-Sergany, E. F., Taha, M. M., El-Helw, H. A., El-Meneisy, A. A.   +5 more
core   +1 more source

A Report of a patient with Diarrhea: Pseudomembranous Colitis

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2016
Background and Objectives: Pseudomembranous colitis is an advanced form of infection with clostridium difficile, which damage epithelial cells following colonization in the intestine and production of toxins A and B.
Ahmad Hormati, Mohammad Reza Ghadir, Seyed Saeed Sarkeshikian, Mahdi Mahdi Pezeshki Modarres, Faezeh Alemi, Mahdieh Ghoddoosi   +5 more
doaj  

Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases

Neuroprotection, Volume 3, Issue 2, Page 120-130, June 2025.
The abstract depicts the gut‐brain axis, illustrating the bidirectional communication between the gastrointestinal tract and the central nervous system. Probiotics can induce the production of neurotrophins, neurotransmitters, SCFAs, and contribute to increased antioxidant levels, which can benefit brain health. In contrast, antibiotics can disrupt the
Tobiloba S. Olajide, Omamuyovwi M. Ijomone   +1 more
wiley   +1 more source

Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases

Advanced Science, Volume 12, Issue 13, April 3, 2025.
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou, Jiachen Yu, Yongshuang Li, Duoyi Zhao, Zhiyu Zhang   +4 more
wiley   +1 more source

Role of microbiota in pain: From bench to bedside

iMetaOmics, Volume 2, Issue 1, March 2025.
Pain is closely linked to microbes. The microbiota modulates pain perception through three mechanisms: microbiota‐derived metabolites, immunoregulation, and direct stimulation on neurons. Therapeutic strategies like probiotics, fecal microbiota transplantation, and dietary changes show significant potential in pain management.
Huiguang Ren, Bo Cao, Qixuan Xu, Ruiyang Zhao, Hanghang Li, Bo Wei   +5 more
wiley   +1 more source

Integrated Analysis of Vonoprazan Safety for Symptomatic Gastro‐Oesophageal Reflux Disease or Erosive Oesophagitis

Alimentary Pharmacology &Therapeutics, Volume 61, Issue 5, Page 835-851, March 2025.
The safety of vonoprazan was evaluated in an integrated analysis of data from clinical trials and post‐marketing experience in adults with symptomatic gastro‐oesophageal reflux disease or erosive oesophagitis. Vonoprazan was well tolerated, with a similar safety profile to proton pump inhibitor comparators.
Colin W. Howden, Philip Katz, Kenneth R. DeVault, David C. Metz, David Tamene, Neila Smith, Barbara Hunt, Yu‐Ming Chang, Stuart J. Spechler   +8 more
wiley   +1 more source

Harnessing the gut microbiome to enhance cancer immunotherapy: Current advances and future directions in microbiota‐based therapeutic strategies

MedComm – Future Medicine, Volume 3, Issue 4, December 2024.
Multiple roles of gut microbiota in tumor immunotherapy. Gut microbiota plays a crucial role in programming innate and acquired immune responses, often affecting immunotherapy efficacy. They serve as biomarkers of efficacy and prognosis, and provide insights into microbiota‐based therapeutic strategies.
Binyan Zhao, Bailing Zhou, Qing Li, Chunyan Su, Jing Ma, Li Yang   +5 more
wiley   +1 more source