Results 51 to 60 of about 32,093 (209)

Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases

open access: yesNeuroprotection, Volume 3, Issue 2, Page 120-130, June 2025.
The abstract depicts the gut‐brain axis, illustrating the bidirectional communication between the gastrointestinal tract and the central nervous system. Probiotics can induce the production of neurotrophins, neurotransmitters, SCFAs, and contribute to increased antioxidant levels, which can benefit brain health. In contrast, antibiotics can disrupt the
Tobiloba S. Olajide   +1 more
wiley   +1 more source

Clostridium difficile in the ICU [PDF]

open access: yes, 2017
Clostridium difficile has become an increasingly common infectious agent in the healthcare setting. It is generally associated with antibiotic use and causes diarrhea as well as other complications such as pseudomembranous colitis (PMC) and toxic ...
Herndon, David N.   +3 more
core   +2 more sources

Advances in Fecal Microbiota Transplantation for Gut Dysbiosis‐Related Diseases

open access: yesAdvanced Science, Volume 12, Issue 13, April 3, 2025.
This article reviews the use of fecal microbiota transplantation (FMT) to treat intestinal diseases like recurrent Clostridioides difficile infection (rCDI), inflammatory bowel disease (IBD), and irritable bowel syndrome (IBS). It discusses FMT's efficacy, influencing factors such as donor selection, recipient characteristics, and treatment protocols ...
Shuna Hou   +4 more
wiley   +1 more source

A Report of a patient with Diarrhea: Pseudomembranous Colitis

open access: yesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Qum, 2016
Background and Objectives: Pseudomembranous colitis is an advanced form of infection with clostridium difficile, which damage epithelial cells following colonization in the intestine and production of toxins A and B.
Ahmad Hormati   +5 more
doaj  

Role of microbiota in pain: From bench to bedside

open access: yesiMetaOmics, Volume 2, Issue 1, March 2025.
Pain is closely linked to microbes. The microbiota modulates pain perception through three mechanisms: microbiota‐derived metabolites, immunoregulation, and direct stimulation on neurons. Therapeutic strategies like probiotics, fecal microbiota transplantation, and dietary changes show significant potential in pain management.
Huiguang Ren   +5 more
wiley   +1 more source

Response to Drs. Borges and Klompmaker [PDF]

open access: yes, 1991
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/73735/1/j.1572-0241.1991.tb07144.x ...
Ruffin, Mack T.
core   +1 more source

Integrated Analysis of Vonoprazan Safety for Symptomatic Gastro‐Oesophageal Reflux Disease or Erosive Oesophagitis

open access: yesAlimentary Pharmacology &Therapeutics, Volume 61, Issue 5, Page 835-851, March 2025.
The safety of vonoprazan was evaluated in an integrated analysis of data from clinical trials and post‐marketing experience in adults with symptomatic gastro‐oesophageal reflux disease or erosive oesophagitis. Vonoprazan was well tolerated, with a similar safety profile to proton pump inhibitor comparators.
Colin W. Howden   +8 more
wiley   +1 more source

Harnessing the gut microbiome to enhance cancer immunotherapy: Current advances and future directions in microbiota‐based therapeutic strategies

open access: yesMedComm – Future Medicine, Volume 3, Issue 4, December 2024.
Multiple roles of gut microbiota in tumor immunotherapy. Gut microbiota plays a crucial role in programming innate and acquired immune responses, often affecting immunotherapy efficacy. They serve as biomarkers of efficacy and prognosis, and provide insights into microbiota‐based therapeutic strategies.
Binyan Zhao   +5 more
wiley   +1 more source

Microbes as medicine

open access: yesAnnals of the New York Academy of Sciences, Volume 1541, Issue 1, Page 63-82, November 2024.
The explosion of research into the human microbiome has revealed the many ways in which our microbes enhance our health. Could these host‐associated microbes be exploited as novel therapies to treat disease? In this review, the various strategies for using microbes as medicine that have been thus far employed, as well as the potential new treatments of
Brendan A. Daisley, Emma Allen‐Vercoe
wiley   +1 more source

The Role of Microbiome and Probiotics in Chemo‐Radiotherapy‐Induced Diarrhea: A Narrative Review of the Current Evidence

open access: yesCancer Reports, Volume 7, Issue 10, October 2024.
ABSTRACT Background In this article, we review the most recent research on probiotics effects on diarrhea in both human and animal models of the condition along with the therapeutic potential of these compounds based on their findings. Recent Findings Nearly 50%–80% of cancer patients experience chemotherapy‐induced diarrhea (CID), serious ...
Sanaz Khorashadizadeh   +4 more
wiley   +1 more source

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