Results 101 to 110 of about 83,379 (284)

The Neonatal Microbiome and Necrotizing Enterocolitis. [PDF]

open access: yes, 2010
Necrotizing enterocolitis (NEC) is a devastating disorder that affects approximately 10% of premature infants. Its mortality remains high (15-30%), and its cause remains unknown.
Aaron Hamvas   +7 more
core   +2 more sources

Outcomes and adverse effects of teduglutide treatment with periodic withdrawal in pediatric short bowel patients

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives We evaluated the efficacy and safety of teduglutide in a real‐world cohort in which national reimbursement policies required treatment interruptions. The primary outcomes were reduction in parenteral support (PS) and treatment‐related adverse effects, and the secondary outcome was the impact of the mandated withdrawal periods ...
Riikka Gunnar   +3 more
wiley   +1 more source

Updated ERNICA guidelines for the management of rectosigmoid Hirschsprung's disease 2025

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives To revise the 2018 European Reference Network for rare Inherited and Congenital Digestive and Gastrointestinal Anomalies (ERNICA) clinical guideline for the management of rectosigmoid Hirschsprung's disease (HSCR) based on new evidence and evolving clinical priorities, ensuring continued relevance, trustworthiness, and consistency ...
Daniel Rossi   +35 more
wiley   +1 more source

A novel central line securement vest reduces line trauma and improves quality of life in patients with intestinal failure

open access: yesJPGN Reports, EarlyView.
Abstract Objective We sought to assess the impact of a novel central line securement vest on the rate of line complications (trauma, infections, and replacements), and measures of quality of life (QOL) in pediatric patients with intestinal failure. Methods We enrolled patients at a single tertiary pediatric center.
Ryan E. St. Pierre‐Hetz   +6 more
wiley   +1 more source

Glutamine and partially hydrolyzed guar gum promote intestinal adaptation and modulate small intestinal microbiota in high‐output stoma: A case report

open access: yesJPGN Reports, EarlyView.
Abstract We report a case of a very low‐birth‐weight infant with a high‐output stoma following necrotizing enterocolitis. The patient exhibited villous atrophy and microbial dysbiosis. Supplementation with glutamine and partially hydrolyzed guar gum (PHGG) was initiated, leading to reduced stoma output, improved feeding tolerance, and appropriate ...
Yunosuke Kawaguchi   +12 more
wiley   +1 more source

Immunopathological properties of the Campylobacter jejuni flagellins and the adhesin CadF as assessed in a clinical murine infection model [PDF]

open access: yes, 2019
Background: Campylobacter jejuni infections constitute serious threats to human health with increasing prevalences worldwide. Our knowledge regarding the molecular mechanisms underlying host-pathogen interactions is still limited.
Backert, Steffen   +7 more
core   +4 more sources

Osmolality of fortified human milk with contemporary human milk fortifiers

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Human milk fortification is critical to support preterm infant growth. Human milk fortifed to caloric densities above manufacturers’ recommendations are often necessary to achieve adequate growth. Fortified milk may be prepared 12–24 h before feeding, although practice variations exist.
Abigail Gardiner   +5 more
wiley   +1 more source

Born too early and too small: higher order cognitive function and brain at risk at ages 8–16 [PDF]

open access: yes, 2019
Prematurity presents a risk for higher order cognitive functions. Some of these deficits manifest later in development, when these functions are expected to mature. However, the causes and consequences of prematurity are still unclear.
Clark, Chris A.   +12 more
core   +6 more sources

Growth and human milk intake outcomes from postdischarge feedings among very‐low‐birth‐weight preterm infants: A systematic review

open access: yesNutrition in Clinical Practice, EarlyView.
Abstract Background Preterm infants of <34 weeks gestation or <1500 g are at risk for postnatal growth failure and often require nutrition support after discharge. Despite expert recommendations for postdischarge human milk (HM) fortification or nutrient‐enriched formula feeding, the effects of current feeding strategies on growth and HM intake remain ...
Tara Rebele   +5 more
wiley   +1 more source

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