Results 121 to 130 of about 111,041 (347)

Vedolizumab treatment for immune checkpoint inhibitor-induced enterocolitis

open access: yesCancer Immunology and Immunotherapy, 2017
Immune checkpoint inhibitors (ICPI), such as ipilimumab [anti-cytotoxic T-lymphocyte antigen-4 (CTLA-4) antibody] and nivolumab or pembrolizumab [anti-programmed cell death protein-1 (PD-1) antibodies], improve survival in several cancer types.
V. Bergqvist   +7 more
semanticscholar   +1 more source

Effectiveness and Safety of Guselkumab in Patients With Moderate‐to‐Severe Plaque Psoriasis in Real‐World Practice in Korea: A Prospective, Multicenter, Observational, Postmarketing Surveillance Study

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Clinical trials have demonstrated the efficacy and safety of guselkumab in patients with moderate‐to‐severe plaque psoriasis. Real‐world evidence for guselkumab in Korea is needed to establish drug safety and effectiveness under real‐world practice in this population.
Bong Seok Shin   +13 more
wiley   +1 more source

Enteral lactoferrin supplementation for prevention of sepsis and necrotizing enterocolitis in preterm infants.

open access: yesCochrane Database of Systematic Reviews, 2017
BACKGROUND Lactoferrin, a normal component of human colostrum and milk, can enhance host defenses and may be effective for prevention of sepsis and necrotizing enterocolitis (NEC) in preterm neonates. OBJECTIVES Primary objective 1.
M. Pammi, G. Suresh
semanticscholar   +1 more source

Impact of Implementation Tools for Spontaneous Preterm Birth Guidelines: A Systematic Review and Meta‐Analysis

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background Preterm birth is a priority area for practice improvement internationally. Clinical practice guidelines improve the efficiency of clinical decision‐making and, when implemented effectively, may advance the quality and consistency of care. Guideline implementation tools may help to further optimise the use of guidelines.
Briar Hunter   +6 more
wiley   +1 more source

Isolation and genotyping of Clostridium perfringens and Clostridium difficile in Capuchin Monkeys (Sapajus spp.)

open access: yesCiência Rural, 2017
: The importance of Clostridium perfringens and C. difficile for most wild animal species remains unclear. This study aimed to isolate and genotype C. perfringens and C.
Rodrigo Otávio Silveira Silva   +5 more
doaj   +1 more source

Necrotizing enterocolitis: Pathophysiology from a historical context.

open access: yesSeminars in Pediatric Surgery, 2018
Necrotizing enterocolitis (NEC) continues to afflict approximately 7% of preterm infants born weighing less than 1500g, though recent investigations have provided novel insights into the pathogenesis of this complex disease.
D. Hackam, M. Caplan
semanticscholar   +1 more source

Economic Impact of Severe Early‐Onset Foetal Growth Restriction: A Multicentre Prospective Cohort Study

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Foetal growth restriction (FGR) affects 10% of pregnancies, contributing to 30% of stillbirths. Current management of early‐onset FGR (< 32 + 0 weeks' gestation) delivers the foetus before stillbirth or irreversible organ damage. The resulting preterm births create additional risks independent of FGR.
George Bray   +20 more
wiley   +1 more source

Sialic acid utilization by Cronobacter sakazakii [PDF]

open access: yes, 2013
Background: The Cronobacter genus is composed of seven species, and can cause infections in all age groups. Of particular concern is C. sakazakii, as this species is strongly associated with severe and often fatal cases of necrotizing enterocolitis and ...
Forsythe, S   +3 more
core   +1 more source

Risk factors for necrotizing enterocolitis in neonates: a systematic review of prognostic studies

open access: yesBMC Pediatrics, 2017
BackgroundNecrotizing enterocolitis (NEC) is a severe multifactorial disease in preterm neonates associated with high morbidity and mortality. Better insight into prognostic values of the many reported factors associated with NEC is needed to enable ...
N. Samuels   +4 more
semanticscholar   +1 more source

Imaging of Abdominal Complications in Children With Acute Lymphoblastic Leukaemia

open access: yesJournal of Medical Imaging and Radiation Oncology, EarlyView.
ABSTRACT Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and remains one of the most common causes of cancer‐related death in children and adolescents. Five‐year overall survival rates now exceed 90% with current multidrug chemotherapeutic regimens. This improvement, coupled with the toxicity of chemotherapy, has led to the
Luke R. Holmes   +2 more
wiley   +1 more source

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