Results 71 to 80 of about 117,551 (361)

Cytomegalovirus haemorrhagic enterocolitis associated with severe infection with COVID-19

BMJ Open Gastroenterology, 2021
We present a case of haemorrhagic enterocolitis in a patient with SARS-CoV-2 who recovered from respiratory failure after support with venovenous extracorporeal membrane oxygenation.
Warren Carll, M. Rady, M. Salomao, Bhavesh M Patel, Vijay P. Singh, Ayan Sen   +5 more
semanticscholar   +1 more source

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Clostridium perfringens α and β recombinant toxoids in equine immunization [PDF]

Pesquisa Veterinária Brasileira, 2020
: Clostridium perfringens is considered one of the main causative agents of superacute enterocolitis, usually fatal in the equine species, due to the action of the β toxin, and is responsible for causing severe myonecrosis, by the action of the α toxin ...
Nayra F.Q.R. Freitas, José D. Barbosa, Denis Y. Otaka, Marcos Roberto A. Ferreira, Rafael R. Rodrigues, Clóvis Moreira Jr, Fabricio R. Conceição, Felipe M. Salvarani   +7 more
doaj   +1 more source

New architectural design of delivery room reduces morbidity in preterm neonates: a prospective cohort study [PDF]

, 2016
Background: A multidisciplinary committee composed of a panel of experts, including a member of the American Academy of Pediatrics and American Institute of Architects, has suggested that the delivery room (DR) and the neonatal intensive care units (NICU)
Aleandri, Vincenzo, Bacchio, Erica, CONTE, FRANCESCA, De Curtis, Mario, Di Chiara, Maria, Messina, Francesco, Scipione, Antonella, Terrin, Gianluca   +7 more
core   +1 more source

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

British Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul, H. Rob Taal, Jan Mazela, Ryszard Lauterbach, Irwin K. M. Reiss, Karel Allegaert, Robert B. Flint, Sinno H. P. Simons   +7 more
wiley   +1 more source

Infectious diseases dynamics in growing/finishing pigs in Southern Brazil (2005-2016) [PDF]

Pesquisa Veterinária Brasileira, 2020
: This study aimed to determine the frequency and distribution of infectious diseases diagnosed through necropsy examination and histopathological analysis in growing/finishing pigs along 12 years (2005-2016) in Southern Brazil.
Guilherme Konradt, Daniele M. Bassuino, Lucas C. Siqueira, Matheus V. Bianchi, Luciana Sonne, David Driemeier, Saulo P. Pavarini   +6 more
doaj   +1 more source

Remote ischemic conditioning counteracts the intestinal damage of necrotizing enterocolitis by improving intestinal microcirculation

Nature Communications, 2020
Necrotizing enterocolitis (NEC) is a devastating disease of premature infants with high mortality rate, indicating the need for precision treatment.
Y. Koike, Bo Li, N. Ganji, Haitao Zhu, H. Miyake, Yong Chen, Carol Lee, Maarten Janssen Lok, C. Zozaya, Ethan Lau, Dorothy Lee, S. Chusilp, Zhen Zhang, M. Yamoto, R. Wu, M. Inoue, K. Uchida, M. Kusunoki, P. Delgado-Olguín, L. Mertens, A. Daneman, S. Eaton, P. Sherman, A. Pierro   +23 more
semanticscholar   +1 more source

Clinical Safety of Extended Interval Dosing of Nivolumab in Patients with Melanoma

Clinical Pharmacology &Therapeutics, EarlyView.
Extended interval dosing regimens of immune checkpoint inhibitors have been implemented widely. However, their approval was mainly based on pharmacokinetic modeling and simulations. Consequently, comparative safety data of extended interval dosing regimens in a real‐world setting are limited.
Ruben Malmberg, Maaike M. Hofman, Fatima Ashad, Alaa Daloul, Stefani Oosterveld, Edwin A. Basak, Esther Oomen‐de Hoop, Astrid A. M. van der Veldt, Arjen Joosse, Roelof W. F. van Leeuwen, Ron H. J. Mathijssen   +10 more
wiley   +1 more source

Candida auris, what do paediatricians need to know? [PDF]

, 2018
AW is supported by the Wellcome Trust Strategic Award (grant 097377) and the MRC Centre for Medical Mycology (grant MR/N006364/1) at the University of Aberdeen.Peer reviewedPublisher ...
Warris, Adilia
core   +1 more source

Necrotizing enterocolitis: It’s not all in the gut

Experimental biology and medicine, 2019
Necrotizing enterocolitis is the leading cause of death due to gastrointestinal disease in preterm neonates, affecting 5–12% of neonates born at a very-low birth weight.
Alissa L. Meister, K. Doheny, R. Travagli   +2 more
semanticscholar   +1 more source