Combined analysis of microbial metagenomic and metatranscriptomic sequencing data to assess in situ physiological conditions in the premature infant gut. [PDF]
Microbes alter their transcriptomic profiles in response to the environment. The physiological conditions experienced by a microbial community can thus be inferred using meta-transcriptomic sequencing by comparing transcription levels of specifically ...
Baker, Robyn+8 more
core +2 more sources
Preterm meconium‐stained amniotic fluid: A red flag for infection and adverse perinatal outcomes
Abstract Objective Meconium‐stained amniotic fluid (MSAF) is uncommon in preterm deliveries and raises concerns about maternal and neonatal infectious risks. We aimed to evaluate maternal, perinatal, and microbiological outcomes in preterm deliveries complicated by MSAF compared to clear amniotic fluid (AF) and to assess outcomes in preterm versus term
Raneen Abu Shqara+3 more
wiley +1 more source
Diarrhea is the most common gastrointestinal symptom in HIV-infected patients. The incidence and severity of diarrhea increase with progression of the immune defi ciency.
Yancheva N.+8 more
doaj +1 more source
Problemática da persistência do canal arterial: um vilão ou uma alteração presente ao acaso?
OBJECTIVE: To analyze newborns weighing less than 1500g at birth who developed complications like bronchopulmonary dysplasia, retinopathy of prematurity, peri-intraventricular hemorrhage, pulmo-nary hemorrhage and necrotizing enterocolitis with or ...
Marina Mafra Carvalhais+3 more
doaj +1 more source
Probiotics and necrotizing enterocolitis.
In this review, we summarize existing knowledge regarding the effects of probiotics on necrotizing enterocolitis (NEC). We review the role of the microbiome in NEC and pre-clinical data on mechanisms of probiotic action.
R. M. Patel, Mark A Underwood
semanticscholar +1 more source
Bacteroides fragilis employs bile salt hydrolase to reprogram host bile acid metabolism, generating lithocholic acid that directly blocks porcine deltacoronavirus infection by disrupting spike protein‐aminopeptidase N binding, defining a microbiota‐bile acid antiviral axis with therapeutic potential against coronaviruses.
Ya‐Qing Zhang+12 more
wiley +1 more source
State of the Art Bowel Management for Pediatric Colorectal Problems: Hirschsprung Disease
After an initial pull-though, patients with Hirschsprung disease (HD) can present with obstructive symptoms, Hirschsprung-associated enterocolitis (HAEC), failure to thrive, or fecal soiling.
Elizaveta Bokova+6 more
doaj +1 more source
Bifidobacterium longum subsp. infantis in experimental necrotizing enterocolitis: alterations in inflammation, innate immune response, and the microbiota. [PDF]
BackgroundProbiotics decrease the risk of necrotizing enterocolitis (NEC). We sought to determine the impact of Bifidobacterium longum subsp. infantis (B. infantis) in the established rat model of NEC.MethodsRat pups delivered 1 d prior to term gestation
Arriola, Jennifer+8 more
core +1 more source
Loss of murine Paneth cell function alters the immature intestinal microbiome and mimics changes seen in neonatal necrotizing enterocolitis [PDF]
Necrotizing enterocolitis (NEC) remains the leading cause of gastrointestinal morbidity and mortality in premature infants. Human and animal studies suggest a role for Paneth cells in NEC pathogenesis.
Elgin, Timothy G+11 more
core +3 more sources
Initially, 166 subjects aged 65 years or older with severe LRTIs met the diagnostic criteria, but 30 cases were excluded due to incomplete clinical data, and 17 cases were excluded due to the presence of malignancies, connective tissue diseases, or long‐term use of immunosuppressive agents. Ultimately, 119 patients were included in the study. The study
Tianqi Qi+8 more
wiley +1 more source