Results 161 to 170 of about 10,616,742 (287)
International Journal of Cancer, Volume 157, Issue 12, Page 2619-2634, 15 December 2025.What's New? Patient‐derived organoids provide a promising platform for modeling colorectal cancer. The authors demonstrated that organoids derived from normal colorectal tissue recapitulate the cellular composition and differentiation trajectory of colorectal crypts.
Zhijun Yu +12 more
wiley +1 more source
Intestinal Stem Cells Exhibit Conditional Circadian Clock Function
Stem Cell Reports, 2018 Summary: The circadian clock is a molecular pacemaker that produces 24-hr physiological cycles known as circadian rhythms. How the clock regulates stem cells is an emerging area of research with many outstanding questions.
Kathyani Parasram +6 more
doaj +1 more source
A High-Throughput Automated Microfluidic Platform for Calcium Imaging of Taste Sensing
Molecules, 2016 The human enteroendocrine L cell line NCI-H716, expressing taste receptors and taste signaling elements, constitutes a unique model for the studies of cellular responses to glucose, appetite regulation, gastrointestinal motility, and insulin secretion ...
Yi-Hsing Hsiao +2 more
doaj +1 more source
Transdifferentiation of Enteroendocrine K-cells into Insulin-expressing Cells
Korean Diabetes Journal, 2009 Background: Despite a recent breakthough in human islet transplantation for treating type 1 diabetes mellitus, the limited availability of donor pancreases remains a major obstacle. Endocrine cells within the gut epithelium (enteroendocrine cells) and pancreatic β cells share similar pathways of differentiation during embryonic development.
Esder Lee +7 more
openaire +1 more source
Let-7e-5p Regulates GLP-1 Content and Basal Release From Enteroendocrine L Cells From DIO Male Mice [PDF]
, 2019 Sandra Handgraaf +4 more
openalex +1 more source
Role of FFAR3 in ketone body regulated glucagon-like peptide 1 secretion
Biochemistry and Biophysics ReportsBackground: Roux-en-Y gastric bypass (RYGB) is an effective treatment for obesity, resulting in long-term weight loss and rapid remission of type 2 diabetes mellitus.
Sara MT. Persson +5 more
doaj +1 more source
Regulation of enteroendocrine cell respiration by the microbial metabolite hydrogen sulfide. [PDF]
Front Endocrinol (Lausanne), 2023 Larraufie P +4 more
europepmc +1 more source
MicroorganismsGlucagon-like peptide-1 (GLP-1) is a hormone secreted from enteroendocrine cells that can promote weight loss and blood glucose improvement. We screened probiotic strains that effectively stimulate GLP-1 secretion from human enteroendocrine cells and ...
A-Ram Kim +7 more
doaj +1 more source