Results 131 to 140 of about 2,029 (168)

An Open-Format Enteroid Culture System for Interrogation of Interactions Between Toxoplasma gondii and the Intestinal Epithelium [PDF]

open access: yesFrontiers in Cellular and Infection Microbiology, 2019
When transmitted through the oral route, Toxoplasma gondii first interacts with its host at the small intestinal epithelium. This interaction is crucial to controlling initial invasion and replication, as well as shaping the quality of the systemic ...
Lisa Luu   +2 more
exaly   +4 more sources

Synchronous enteroid adenocarcinoma at the ureteral implantation site after ureterosigmoidostomy

open access: yesUrology Case Reports, 2022
Ureterosigmoidostomy is considered to be the oldest urinary diversion technique performed for the first time in the 19th Century in patients with urinary malformations. However, the high rate of complications as well as the significant risk of developing
B Gomez Gonzalez
exaly   +2 more sources

A primary human macrophage-enteroid co-culture model to investigate mucosal gut physiology and host-pathogen interactions

open access: yesScientific Reports, 2017
Integration of the intestinal epithelium and the mucosal immune system is critical for gut homeostasis. The intestinal epithelium is a functional barrier that secludes luminal content, senses changes in the gut microenvironment, and releases immune ...
Nicholas W Baetz   +2 more
exaly   +2 more sources

Intestinal organoid/enteroid-based models for Cryptosporidium

open access: yesCurrent Opinion in Microbiology, 2020
Cryptosporidium is a leading cause of diarrhea and death in young children and untreated AIDS patients in resource-poor settings, and of waterborne outbreaks of disease in developed countries. However, there is no consistently effective treatment for vulnerable populations.
Honorine D Ward
exaly   +3 more sources

Functional assays with human patient-derived enteroid monolayers to assess the human gut barrier [PDF]

open access: yesSTAR Protocols, 2021
Summary: Here, we describe the use of polarized patient enteroid-derived monolayers (EDMs) to assess the impact of e-cigarettes on the human gut barrier. These EDMs can be adapted to culture in a 96-well plate for high-throughput screening.
Ibrahim M Sayed   +2 more
exaly   +2 more sources

A Novel Human Epithelial Enteroid Model of Necrotizing Enterocolitis [PDF]

open access: yesJournal of Visualized Experiments, 2019
Necrotizing enterocolitis (NEC) is a devastating disease of newborn infants. It is characterized by multiple pathophysiologic alterations in the human intestinal epithelium, leading to increased intestinal permeability, impaired restitution, and increased cell death.
Christie Buonpane, Catherine J Hunter
exaly   +5 more sources
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Quantification of Proliferative and Dead Cells in Enteroids

Journal of Visualized Experiments, 2020
The intestinal epithelium acts as a barrier that prevents luminal contents, such as pathogenic microbiota and toxins, from entering the rest of the body. Epithelial barrier function requires the integrity of intestinal epithelial cells. While epithelial cell proliferation maintains a continuous layer of cells that forms a barrier, epithelial damage ...
Hua-Shan, Li   +11 more
openaire   +2 more sources

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