Results 171 to 180 of about 2,925 (189)

Testing Epithelial Permeability in Fetal Tissue-Derived Enteroids

Journal of Visualized Experiments, 2022
Human fetal tissue-derived enteroids are emerging as a promising in vitro model to study intestinal injuries in preterm infants. Enteroids exhibit polarity, consisting of a lumen with an apical border, tight junctions, and a basolateral outer layer exposed to growth media.
Amelia, Llerena, Shaheda, Urmi, Jahanshah, Amin, Byeong, Cha, Thao Tb, Ho   +4 more
openaire   +2 more sources

Establishment of MDR1-knockout human enteroids for pharmaceutical application

Drug Metabolism and Pharmacokinetics, 2023
In the drug development process, it is important to assess the contributions of drug-metabolizing enzymes and/or drug transporters to the intestinal pharmacokinetics of candidate compounds. For such assessments, chemical inhibitors are often used in in vitro systems.
Tatsuya Inui, Ryuga Nomoto, Jumpei Yokota, Tomoki Yamashita, Kentaro Okada, Wataru Kishimoto, Hiroshi Nakase, Hiroyuki Mizuguchi   +7 more
openaire   +2 more sources

Generation and Quantitative Imaging of Enteroid Monolayers

2020
The intestinal epithelium is a single layer of cells that plays a critical role in digestion, absorbs nutrients from food, and coordinates the delicate interplay between microbes in the gut lumen and the immune system. Epithelial homeostasis is crucial for maintaining health; disruption of homeostasis results in disorders including inflammatory bowel ...
Laura E, Sanman, Ina W, Chen, Jake M, Bieber, Curtis A, Thorne, Lani F, Wu, Steven J, Altschuler   +5 more
openaire   +2 more sources

Quantification of Proliferative and Dead Cells in Enteroids

Journal of Visualized Experiments, 2020
The intestinal epithelium acts as a barrier that prevents luminal contents, such as pathogenic microbiota and toxins, from entering the rest of the body. Epithelial barrier function requires the integrity of intestinal epithelial cells. While epithelial cell proliferation maintains a continuous layer of cells that forms a barrier, epithelial damage ...
Hua-Shan, Li, Shao-Fang, Xu, Jian-Ying, Sheng, Zhi-Hui, Jiang, Jing, Wang, Ning, Ding, Tao, Wang, Matthew A, Odenwald, Jerrold R, Turner, Wei-Qi, He, Hong, Xu, Juan-Min, Zha   +11 more
openaire   +2 more sources

Effect of essential amino acids on enteroids: Methionine deprivation suppresses proliferation and affects differentiation in enteroid stem cells

Biochemical and Biophysical Research Communications, 2017
We investigated the effects of essential amino acids on intestinal stem cell proliferation and differentiation using murine small intestinal organoids (enteroids) from the jejunum. By selectively removing individual essential amino acids from culture medium, we found that 24 h of methionine (Met) deprivation markedly suppressed cell proliferation in ...
Yuki, Saito, Ken, Iwatsuki, Hikaru, Hanyu, Natsuki, Maruyama, Eitaro, Aihara, Miki, Tadaishi, Makoto, Shimizu, Kazuo, Kobayashi-Hattori   +7 more
openaire   +2 more sources

Wnt Signaling Inhibition Induces Lateral Lumens in Enteroids

The FASEB Journal, 2022
Background To overcome the constant shedding of the intestinal epithelium, the stem cells at the base of the crypt rapidly proliferate and differentiate into epithelial cells necessary for proper intestinal function.
Andreanna Burman, James R. Goldenring, Izumi Kaji   +2 more
openaire   +1 more source

[Retroperitoneal enteroid cyst].

Journal de chirurgie, 1976
The author report a case of enteroid retroperitoneal cyst treated by enucleation. Such a lesion raises mainly the problem of histological recognition and embryological interpretation for which there are two possible theories: (1) Uptake, before sealing off of the embryo, of a cell group of endoblastic origin which develops some distance from the ...
J C, Patel, F, Monneins, A, Louvel
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enteroid, adj.

2023
openaire   +1 more source

Pararectal enteroid cyst.

Lyon chirurgical, 2008
A, RICARD, R, GIGNOUX
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Development and characterization of mouse small intestinal enteroids

Journal of the Preventive Veterinary Medicine, 2020
Siu Lee, Na-Yeon Gu, Se-A Lee, Jienny Lee, Yoon-Hee Lee, Bang-Hun Hyun   +5 more
openaire   +1 more source