Results 71 to 80 of about 2,029 (168)

Video_1_An Open-Format Enteroid Culture System for Interrogation of Interactions Between Toxoplasma gondii and the Intestinal Epithelium.MP4

, 2019
When transmitted through the oral route, Toxoplasma gondii first interacts with its host at the small intestinal epithelium. This interaction is crucial to controlling initial invasion and replication, as well as shaping the quality of the systemic ...
Janine L. Coombes (7319504), Carrie A. Duckworth (7319495), Luke J. Johnston (7319486), Stuart D. Armstrong (7319489), Nadine Randle (7319492), Catherine S. Hartley (6100184), Barry J. Campbell (7319498), Jonathan M. Wastling (7319501), Lisa Luu (7319483), Hayley Derricott (4518250)   +9 more
core   +1 more source

The inhibition of CFA/I-CS21 ETEC adherence to an additional enteroid monolayer by CFA/I-specific, but not CS21-specific, antibodies.

, 2022
Differentiated jejunal enteroid monolayers (J2) were infected with wildtype ETEC strain CVD30 for 4 hrs with or without pre-incubation with anti-CFA/I or anti-CS21 antibody. Monolayers were washed and lysed to quantify adherent bacteria expressed as % of
Emily M. Smith (1326564), Eileen M. Barry (8663025), Christen L. Grassel (13155228), Antonia Papadimas (13155231), Jennifer Foulke-Abel (434893)   +4 more
core   +1 more source

An Adaptable Protocol to Generate a Murine Enteroid-Macrophage Co-Culture System. [PDF]

Int J Mol Sci
Impairment of the intestinal epithelial barrier is frequently seen as collateral damage in various local and systemic inflammatory conditions. The inflammatory process is characterized by reciprocal interactions between the host intestinal epithelium and
Hentschel V, Govindarajan D, Seufferlein T, Armacki M.   +3 more
europepmc   +2 more sources

IFN-γ pretreated enteroid monolayers display enhanced levels of IEC shedding and a dependence on caspase-1 and caspase-11 for restriction of Salmonella infection.

, 2020
Enteroids generated from WT, Casp11−/−, Casp1−/− and Casp1/11−/− mice were treated for 16 h with vehicle control or IFN-γ (10 ng/mL), then cell lysates probed for pro-caspase-1 (p46), pro-caspase-11 (p43) or actin by Western blotting.
Joannie M. Allaire (8704134), Leigh A. Knodler (8704137), Martin Stahl (443478), Shauna M. Crowley (8704131), Bruce A. Vallance (7536416), Xiao Han (102316), Isabella Rauch (423753)   +6 more
core   +1 more source

Equine coronavirus infection and replication in equine intestinal enteroids

Veterinary Research
Abstract In this study, equine intestinal enteroids (EIEs) were generated from the duodenum, jejunum, and ileum and inoculated with equine coronavirus (ECoV) to investigate their suitability as in vitro models with which to study ECoV infection. Immunohistochemistry revealed that the EIEs were composed of various cell types expressed in vivo in
Yoshinori Kambayashi, Manabu Nemoto, Akihiro Ochi, Daiki Kishi, Takanori Ueno, Koji Tsujimura, Hiroshi Bannai, Nanako Kawanishi, Minoru Ohta, Tohru Suzuki   +9 more
openaire   +3 more sources

Human Norovirus Cultivation in Nontransformed Stem Cell-Derived Human Intestinal Enteroid Cultures: Success and Challenges

, 2019
Noroviruses, in the genus Norovirus, are a significant cause of viral gastroenteritis in humans and animals. For almost 50 years, the lack of a cultivation system for human noroviruses (HuNoVs) was a major barrier to understanding virus biology and the ...
Sasirekha Ramani, Frederick H. Neill, Shih-Ching Lin, David Y. Graham, Kosuke Murakami, Antone R. Opekun, Nicolas W. Cortes-Penfield, Robert L. Atmar, Khalil Ettayebi, Mary K. Estes, B. Vijayalakshmi Ayyar, Victoria R. Tenge, Umesh Karandikar, Sue E. Crawford, Kei Haga, James R. Broughman, Xi-Lei Zeng, Sarah E. Blutt   +17 more
core   +1 more source

Working with patient-derived enteroids and colonoids v2

, 2023
This is a compilations of protocols for working with patient-derived enteroids or colonoids, from recovery to cryopreservation, in expansion culture (minimal differentiation)
openaire   +1 more source

Working with patient-derived enteroids and colonoids v1

, 2023
This is a compilations of working with patient-derived enteroids or colonoids, from recovery to cryopreservation, in expansion culture (minimal differentiation)
openaire   +1 more source

2025 ACVIM Forum Research Abstract Program

Journal of Veterinary Internal Medicine, Volume 39, Issue 6, November/December 2025.
wiley   +1 more source

Development of an avian enteroid model to study host-bacteria relationship under physioxical conditions

International audienceSalmonellosis is a major food-borne zoonosis. Poultry is the main reservoir of Salmonella Enteritidis. After oral contamination, the chicken intestinal mucosa is the first line of interactions with Salmonella and the caecum is the ...
Velge, Philippe, Virlogeux-Payant, Isabelle, Barilleau, Emilie, Lalmanach, Anne-Christine, Pichon, Julien, Holbert, Sébastien   +5 more
core