Results 91 to 100 of about 46,442 (255)

Th17, intestinal microbiota and the abnormal immune response in the pathogenesis of celiac disease [PDF]

open access: yes, 2015
Celiac disease (CD) is an autoimmune enteropathy induced by the ingestion of gluten in genetically predisposed individuals who carry the HLA-DQ2 or -DQ8 alleles.
Cicerone, Clelia   +2 more
core  

Why is the skeleton still in the hospital closet? A look at the complex aetiology of protein-energy malnutrition and its implications for the nutrition care team [PDF]

open access: yes, 2018
Extract: The acknowledgement of protein-energy malnutrition (PEM) as one of “…the most serious nutritional problems of our time” was actually made by Dr Butterworth Jr in 1974 in his seminal article, “the skeleton in the hospital closet” (1).
Marshall, S.
core   +1 more source

Non-celiac Enteropathies

open access: yesCurrent Gastroenterology Reports
Abstract Purpose of Review Non-celiac enteropathies (NCE) can be due to a variety of causes. The workup for NCE includes history, physical, laboratory and histology review and can be difficult. Enteropathies can result in serious illness due to consequences of malabsorption including severe weight loss, nutritional ...
Mi, Kaitlyn, Cao, Scarlett, Adams, Dawn
openaire   +2 more sources

Exploiting ALK inhibition in anaplastic large cell lymphoma: Biological rationale and therapeutic integration

open access: yesBritish Journal of Haematology, EarlyView.
Summary Mature T‐cell lymphomas comprise a heterogeneous group of aggressive non‐Hodgkin lymphomas with limited therapeutic options in the relapsed or refractory setting. Among them, anaplastic lymphoma kinase (ALK)‐positive anaplastic large cell lymphoma (ALCL) represents a biologically distinct subtype driven by constitutive activation of ALK fusion ...
Santino Caserta   +13 more
wiley   +1 more source

Effects of corn oil ingestion on the intestinal mucosa of normal dogs

open access: yesFrontiers in Veterinary Science
IntroductionWe assessed corn oil’s oral effectiveness in detecting small bowel changes in healthy dogs through ultrasonography, endoscopy, and histopathology.
Su-Jin An   +3 more
doaj   +1 more source

Drug interactions may be important risk factors for methotrexate neurotoxicity, particularly in pediatric leukemia patients [PDF]

open access: yes, 2016
Purpose: Methotrexate administration is associated with frequent adverse neurological events during treatment for childhood acute lymphoblastic leukemia.
Baird, Susan F.   +5 more
core   +2 more sources

Modulation of KATP channels by diazoxide preserves mitochondrial function and barrier integrity under staurosporine‐induced epithelial stress

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Intestinal barrier dysfunction caused by mitochondrial stress, oxidative damage and apoptosis, are hallmarks of dysbiosis‐associated gastrointestinal (GI) disorders. Staurosporine causes downstream features of dysbiosis‐induced epithelial damage.
Fatima Maqoud   +9 more
wiley   +1 more source

Chapter Five. Systematic review results by biomarker classifications [PDF]

open access: yes, 2016
5.1 Markers of Absorption and Permeability Overview 5.2 Markers of Absorption 5.3 Markers of Permeability 5.4 Markers of Digestion 5.5 Markers of Intestinal Inflammation and Intestinal Immune Activation 5.6 Markers of Systemic Inflammation and Systemic ...
Denno, Donna M   +4 more
core   +1 more source

Portal hypertensive enteropathy

open access: yesWorld Journal of Hepatology, 2014
Portal hypertensive enteropathy (PHE) is a condition that describes the pathologic changes and mucosal abnormalities observed in the small intestine of patients with portal hypertension. This entity is being increasingly recognized and better understood over the past decade due to increased accessibility of the small intestine made possible by the ...
Parit, Mekaroonkamol   +2 more
openaire   +2 more sources

Expanding Phenotype of GINS1 Deficiency: A Case Report and Review of the Literature

open access: yesClinical Genetics, EarlyView.
The authors present a novel case and review of individuals with GINS1 deficiency, causing severe growth restriction and combined immunodeficiency. Only the ninth case of this ultrarare disorder, it highlights the role of these variants in disease, glaucoma as a feature, and the possibility of immunodeficiency without infections in affected individuals.
Michael P. Mackley   +6 more
wiley   +1 more source

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