Results 91 to 100 of about 1,444 (144)

Mismatch Repair Proteins Initiate Epigenetic Alterations during Inflammation-Driven Tumorigenesis [PDF]

open access: yes, 2017
Aberrant silencing of genes by DNA methylation contributes to cancer, yet how this process is initiated remains unclear. Using a murine model of inflammation-induced tumorigenesis, we tested the hypothesis that inflammation promotes recruitment of ...
Ashley R. Maiuri   +8 more
core   +1 more source

E-cadherin and APC in early-onset colorectal cancer [PDF]

open access: yes, 2020
Colorectal cancer (CRC) is a considerable health burden being the second highest cause of cancer deaths globally. While overall cases of CRC have been declining worldwide, there has been an increase in the incidence of the disease among patients under 50
Aitchison, Alan
core  

The myeloid immune signature of Enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis [PDF]

open access: yes, 2018
Enterotoxigenic Bacteroides fragilis (ETBF), a human commensal and candidate pathogen in colorectal cancer (CRC), is a potent initiator of IL-17-dependent colon tumorigenesis in Min mice.
Thiele Orberg, Erik Thiele
core  

FASEB J [PDF]

open access: yes
Enterotoxigenic Bacteroides fragilis (ETBF) is a commensal bacterium of great importance to human health due to its ability to induce colitis and cause colon tumor formation in mice through the production of B. fragilis toxin (BFT).

core  

Keystone pathobionts associated with colorectal cancer promote oncogenic reprograming.

open access: yesPLoS ONE
Fusobacterium nucleatum (Fn) and enterotoxigenic Bacteroides fragilis (ETBF) are two pathobionts consistently enriched in the gut microbiomes of patients with colorectal cancer (CRC) compared to healthy counterparts and frequently observed for their ...
Josh Jones   +3 more
doaj   +1 more source

Conventional and molecular methods in the diagnosis of community-acquired diarrhoea in children under 5 years of age from the north-eastern region of Poland

open access: yesInternational Journal of Infectious Diseases, 2015
Objectives: The purpose of this study was to determine the main causative agents of community-acquired acute diarrhoea in children using conventional methods and PCR. Methods: Stool samples were collected from 100 children under 5 years of age with acute
Krzysztof Fiedoruk   +6 more
doaj   +1 more source

Host-Microbe Interactions and the Developing Gut Microbiome in Infants with Cystic Fibrosis [PDF]

open access: yes
Cystic Fibrosis (CF) is a progressive genetic disease that leads to dysfunction of ion transport across epithelial cell membranes. A major hallmark in CF is chronic inflammation in the intestine, though the mechanisms by which this occurs are still ...
Salerno, Paige E
core   +1 more source

Dissecting Gut‐Microbial Community Interactions using a Gut Microbiome‐on‐a‐Chip

open access: yesAdvanced Science
While the human gut microbiota has a significant impact on gut health and disease, understanding of the roles of gut microbes, interactions, and collective impact of gut microbes on various aspects of human gut health is limited by the lack of suitable ...
Jeeyeon Lee   +2 more
doaj   +1 more source

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